abnormal long term depression Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description change from the normal, persistent activity-dependent decrease in synaptic efficacy between neurons, often following slow, weak stimulation of neurons (Mammalian Phenotype Ontology, MP_0001898)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001898
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Genes

66 gene mutations causing the abnormal long term depression phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADCY8 adenylate cyclase 8 (brain)
AKAP5 A kinase (PRKA) anchor protein 5
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ATAD1 ATPase family, AAA domain containing 1
BACE1 beta-site APP-cleaving enzyme 1
CALY calcyon neuron-specific vesicular protein
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CBLN1 cerebellin 1 precursor
CD247 CD247 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRM1 cholinergic receptor, muscarinic 1
CNR1 cannabinoid receptor 1 (brain)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
DAGLA diacylglycerol lipase, alpha
DPYSL5 dihydropyrimidinase-like 5
DRD2 dopamine receptor D2
EFNB3 ephrin-B3
FMR1 fragile X mental retardation 1
FOXP2 forkhead box P2
GFAP glial fibrillary acidic protein
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRID2 glutamate receptor, ionotropic, delta 2
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM1 glutamate receptor, metabotropic 1
GRM2 glutamate receptor, metabotropic 2
IQSEC1 IQ motif and Sec7 domain 1
KIF17 kinesin family member 17
LAMA2 laminin, alpha 2
LEPR leptin receptor
LRRC7 leucine rich repeat containing 7
MYO5A myosin VA (heavy chain 12, myoxin)
NLGN3 neuroligin 3
NOS1 nitric oxide synthase 1 (neuronal)
NRGN neurogranin (protein kinase C substrate, RC3)
PARK7 parkinson protein 7
PICK1 protein interacting with PRKCA 1
PINK1 PTEN induced putative kinase 1
PLAT plasminogen activator, tissue
PLCB4 phospholipase C, beta 4
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
RALBP1 ralA binding protein 1
RARB retinoic acid receptor, beta
RAVER1 ribonucleoprotein, PTB-binding 1
RIMS1 regulating synaptic membrane exocytosis 1
RYR3 ryanodine receptor 3
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SORCS3 sortilin-related VPS10 domain containing receptor 3
SPRED1 sprouty-related, EVH1 domain containing 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VGF VGF nerve growth factor inducible
WASF1 WAS protein family, member 1
WWC1 WW and C2 domain containing 1