abnormal liver development Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the differentiation of the bile-secreting organ that is important for detoxification, for fat, carbohydrate, and protein metabolism, and for glycogen storage (Mammalian Phenotype Ontology, MP_0000596)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000596
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Genes

46 gene mutations causing the abnormal liver development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
ARF6 ADP-ribosylation factor 6
BMP4 bone morphogenetic protein 4
CBFB core-binding factor, beta subunit
DNM1L dynamin 1-like
FAM20B family with sequence similarity 20, member B
FGFR2 fibroblast growth factor receptor 2
GATA6 GATA binding protein 6
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
HHEX hematopoietically expressed homeobox
HLX H2.0-like homeobox
ICMT isoprenylcysteine carboxyl methyltransferase
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KMT2A lysine (K)-specific methyltransferase 2A
LIG1 ligase I, DNA, ATP-dependent
MAP2K4 mitogen-activated protein kinase kinase 4
MBTD1 mbt domain containing 1
MECOM MDS1 and EVI1 complex locus
MED1 mediator complex subunit 1
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MSX1 msh homeobox 1
MYB v-myb avian myeloblastosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCOA6 nuclear receptor coactivator 6
NF1 neurofibromin 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
PBX1 pre-B-cell leukemia homeobox 1
PDX1 pancreatic and duodenal homeobox 1
PEX11B peroxisomal biogenesis factor 11 beta
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKNOX1 PBX/knotted 1 homeobox 1
PROX1 prospero homeobox 1
PTK2 protein tyrosine kinase 2
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RXRA retinoid X receptor, alpha
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TGFB1 transforming growth factor, beta 1
TGFBR3 transforming growth factor, beta receptor III
UBC ubiquitin C
WT1 Wilms tumor 1
XBP1 X-box binding protein 1