abnormal left-right axis patterning Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ (Mammalian Phenotype Ontology, MP_0001706)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001706
Similar Terms
Downloads & Tools

Genes

53 gene mutations causing the abnormal left-right axis patterning phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2B activin A receptor, type IIB
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ARL13B ADP-ribosylation factor-like 13B
C2CD3 C2 calcium-dependent domain containing 3
CC2D2A coiled-coil and C2 domain containing 2A
CFC1 cripto, FRL-1, cryptic family 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DACT1 dishevelled-binding antagonist of beta-catenin 1
DAND5 DAN domain family member 5, BMP antagonist
DISP1 dispatched homolog 1 (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
FOXJ1 forkhead box J1
GDF1 growth differentiation factor 1
HES7 hes family bHLH transcription factor 7
HIRA histone cell cycle regulator
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFT122 intraflagellar transport 122
IFT172 intraflagellar transport 172
IFT57 intraflagellar transport 57
IFT88 intraflagellar transport 88
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KIAA0586 KIAA0586
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
LEFTY2 left-right determination factor 2
LRP6 low density lipoprotein receptor-related protein 6
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MBD4 methyl-CpG binding domain protein 4
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
NKX3-2 NK3 homeobox 2
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOTO notochord homeobox
NPHP3 nephronophthisis 3 (adolescent)
PBX1 pre-B-cell leukemia homeobox 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PIFO primary cilia formation
PITX2 paired-like homeodomain 2
PKD1L1 polycystic kidney disease 1 like 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RPGRIP1L RPGRIP1-like
SMAD5 SMAD family member 5
SMO smoothened, frizzled class receptor
STIL SCL/TAL1 interrupting locus
SUFU suppressor of fused homolog (Drosophila)
TCTN1 tectonic family member 1
WNT3A wingless-type MMTV integration site family, member 3A
ZIC3 Zic family member 3