abnormal lacrimal apparatus morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the network of orbital structures of the eye that secrete and drain tears from the surface of the eyeball into the nasal cavity; these parts include the lacrimal glands, lacrimal lake, lacrimal ducts, lacrimal canals, lacrimal sacs, nasolacrimal ducts, and lacrimal puncta (Mammalian Phenotype Ontology, MP_0008968)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008968
Similar Terms
Downloads & Tools

Genes

18 gene mutations causing the abnormal lacrimal apparatus morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CCR7 chemokine (C-C motif) receptor 7
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
E2F1 E2F transcription factor 1
FGFR2 fibroblast growth factor receptor 2
FIGN fidgetin
FOXC1 forkhead box C1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KAT6B K(lysine) acetyltransferase 6B
NCDN neurochondrin
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
OTX1 orthodenticle homeobox 1
PAX6 paired box 6
PITX3 paired-like homeodomain 3
PRLR prolactin receptor
SIX1 SIX homeobox 1
TP63 tumor protein p63
VSX2 visual system homeobox 2