abnormal kidney development Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the differentiation of the paired organs responsible for urine secretion (Mammalian Phenotype Ontology, MP_0000527)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000527
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Genes

82 gene mutations causing the abnormal kidney development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGTR2 angiotensin II receptor, type 2
AMER1 APC membrane recruitment protein 1
ARL3 ADP-ribosylation factor-like 3
AXIN1 axin 1
BAG6 BCL2-associated athanogene 6
BCL2 B-cell CLL/lymphoma 2
BDKRB2 bradykinin receptor B2
BICC1 BicC family RNA binding protein 1
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
CBS cystathionine-beta-synthase
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CTNNBIP1 catenin, beta interacting protein 1
DCHS1 dachsous cadherin-related 1
DLG1 discs, large homolog 1 (Drosophila)
EMX2 empty spiracles homeobox 2
EYA1 EYA transcriptional coactivator and phosphatase 1
FAT4 FAT atypical cadherin 4
FGF10 fibroblast growth factor 10
FGF7 fibroblast growth factor 7
FGFR2 fibroblast growth factor receptor 2
FGFRL1 fibroblast growth factor receptor-like 1
FOXC1 forkhead box C1
FOXD1 forkhead box D1
FRAS1 Fraser extracellular matrix complex subunit 1
FREM1 FRAS1 related extracellular matrix 1
GALC galactosylceramidase
GDF11 growth differentiation factor 11
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
GNAS GNAS complex locus
GPC3 glypican 3
GREM1 gremlin 1, DAN family BMP antagonist
GRIP1 glutamate receptor interacting protein 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
ILK integrin-linked kinase
ITGA8 integrin, alpha 8
JMJD6 jumonji domain containing 6
KIF26B kinesin family member 26B
LAMA5 laminin, alpha 5
LAMC1 laminin, gamma 1 (formerly LAMB2)
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHX1 LIM homeobox 1
LRP4 low density lipoprotein receptor-related protein 4
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NF1 neurofibromin 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPNT nephronectin
OSR1 odd-skipped related transciption factor 1
PARVA parvin, alpha
PAX2 paired box 2
PBX1 pre-B-cell leukemia homeobox 1
PEX5 peroxisomal biogenesis factor 5
PLXNB1 plexin B1
POU3F3 POU class 3 homeobox 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTRH2 peptidyl-tRNA hydrolase 2
RDH10 retinol dehydrogenase 10 (all-trans)
RET ret proto-oncogene
RSPO2 R-spondin 2
SALL1 spalt-like transcription factor 1
SIX1 SIX homeobox 1
SIX2 SIX homeobox 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STK36 serine/threonine kinase 36
TCF21 transcription factor 21
TRPS1 trichorhinophalangeal syndrome I
TWSG1 twisted gastrulation BMP signaling modulator 1
VEGFA vascular endothelial growth factor A
WNT11 wingless-type MMTV integration site family, member 11
WNT4 wingless-type MMTV integration site family, member 4
WNT9B wingless-type MMTV integration site family, member 9B
WT1 Wilms tumor 1
XDH xanthine dehydrogenase