abnormal juxtaglomerular apparatus morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the complex of modified smooth muscle cells consisting of juxtaglomerular cells, extraglomerular mesangium lacis cells, the macula densa of the distal convoluted tubule, and granular epithelial peripolar cells; these cells are found in the walls of afferent and efferent glomerular arterioles (Mammalian Phenotype Ontology, MP_0002829)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002829
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Genes

7 gene mutations causing the abnormal juxtaglomerular apparatus morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
BDKRB2 bradykinin receptor B2
NR3C2 nuclear receptor subfamily 3, group C, member 2
REN renin
UMOD uromodulin
WT1 Wilms tumor 1