abnormal interleukin-17 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the production or release of a proinflammatory cytokine produced primarily by T-cells or their precursors (Mammalian Phenotype Ontology, MP_0008680)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008680
Similar Terms
Downloads & Tools

Genes

48 gene mutations causing the abnormal interleukin-17 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BATF basic leucine zipper transcription factor, ATF-like
BHLHE41 basic helix-loop-helix family, member e41
CD274 CD274 molecule
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CLEC6A C-type lectin domain family 6, member A
CRTAM cytotoxic and regulatory T cell molecule
CTLA4 cytotoxic T-lymphocyte-associated protein 4
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FLG filaggrin
GPR15 G protein-coupled receptor 15
HAVCR1 hepatitis A virus cellular receptor 1
IFNG interferon, gamma
IL10RB interleukin 10 receptor, beta
IL12B interleukin 12B
IL17A interleukin 17A
IL17C interleukin 17C
IL17F interleukin 17F
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL17RC interleukin 17 receptor C
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL21R interleukin 21 receptor
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL6 interleukin 6
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MEFV Mediterranean fever
MMP1 matrix metallopeptidase 1
NCKAP1L NCK-associated protein 1-like
NFIL3 nuclear factor, interleukin 3 regulated
NLRP10 NLR family, pyrin domain containing 10
NLRP3 NLR family, pyrin domain containing 3
PLCD1 phospholipase C, delta 1
PRKCQ protein kinase C, theta
RFTN1 raftlin, lipid raft linker 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
TBX21 T-box 21
THBS1 thrombospondin 1
TIMD4 T-cell immunoglobulin and mucin domain containing 4
TNFAIP8L2 tumor necrosis factor, alpha-induced protein 8-like 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSC22D3 TSC22 domain family, member 3
VTCN1 V-set domain containing T cell activation inhibitor 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa