abnormal interleukin-13 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the production or release of a cytokine synthesized by T-cells that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-cells, and appears to play a role in regulating inflammatory and immune responses (Mammalian Phenotype Ontology, MP_0008671)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008671
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Genes

44 gene mutations causing the abnormal interleukin-13 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
CCR1 chemokine (C-C motif) receptor 1
CCR4 chemokine (C-C motif) receptor 4
CCRL2 chemokine (C-C motif) receptor-like 2
CD300A CD300a molecule
CD300LF CD300 molecule-like family member f
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CISH cytokine inducible SH2-containing protein
DUSP4 dual specificity phosphatase 4
FBN1 fibrillin 1
FLG filaggrin
FPR2 formyl peptide receptor 2
GPR84 G protein-coupled receptor 84
HAVCR1 hepatitis A virus cellular receptor 1
HRH1 histamine receptor H1
IL13 interleukin 13
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
IL21R interleukin 21 receptor
IL25 interleukin 25
IL4 interleukin 4
ITK IL2-inducible T-cell kinase
LIG4 ligase IV, DNA, ATP-dependent
LPAR2 lysophosphatidic acid receptor 2
MEFV Mediterranean fever
MMP9 matrix metallopeptidase 9
MUC2 mucin 2, oligomeric mucus/gel-forming
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
NFIL3 nuclear factor, interleukin 3 regulated
NME2 NME/NM23 nucleoside diphosphate kinase 2
POU2AF1 POU class 2 associating factor 1
PRKCQ protein kinase C, theta
RAD50 RAD50 homolog (S. cerevisiae)
RGS16 regulator of G-protein signaling 16
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RSAD2 radical S-adenosyl methionine domain containing 2
SDC1 syndecan 1
SIRT7 sirtuin 7
STIM1 stromal interaction molecule 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSLP thymic stromal lymphopoietin