abnormal interleukin-12b secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the production or release of the p40 cytokine subunit that is a component of both interleukin-12 and interleukin-23 (Mammalian Phenotype Ontology, MP_0008668)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008668
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Genes

27 gene mutations causing the abnormal interleukin-12b secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARRB2 arrestin, beta 2
CARD9 caspase recruitment domain family, member 9
CCL13 chemokine (C-C motif) ligand 13
CD200R1 CD200 receptor 1
CLEC6A C-type lectin domain family 6, member A
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
IFNGR1 interferon gamma receptor 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAVS mitochondrial antiviral signaling protein
MEFV Mediterranean fever
MYD88 myeloid differentiation primary response 88
NFIL3 nuclear factor, interleukin 3 regulated
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR2 toll-like receptor 2
TLR5 toll-like receptor 5
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNIP1 TNFAIP3 interacting protein 1
UNC93B1 unc-93 homolog B1 (C. elegans)
ZC3H12A zinc finger CCCH-type containing 12A