abnormal incisor morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the teeth, normally consisting of two pairs, top and bottom, of the long teeth that are the most anterior and prominent in the jaw (Mammalian Phenotype Ontology, MP_0005358)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005358
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Genes

79 gene mutations causing the abnormal incisor morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACVR2A activin A receptor, type IIA
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AMBN ameloblastin (enamel matrix protein)
AMELY amelogenin, Y-linked
ANTXR1 anthrax toxin receptor 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP7 bone morphogenetic protein 7
CCND1 cyclin D1
CDON cell adhesion associated, oncogene regulated
CHUK conserved helix-loop-helix ubiquitous kinase
CSF1 colony stimulating factor 1 (macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DISP1 dispatched homolog 1 (Drosophila)
DLX5 distal-less homeobox 5
EDA ectodysplasin A
EDAR ectodysplasin A receptor
EDARADD EDAR-associated death domain
ENAM enamelin
EVC Ellis van Creveld protein
EXOC3L2 exocyst complex component 3-like 2
FAM20A family with sequence similarity 20, member A
FGF10 fibroblast growth factor 10
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FIG4 FIG4 phosphoinositide 5-phosphatase
FOXA2 forkhead box A2
FST follistatin
FUZ fuzzy planar cell polarity protein
GJA1 gap junction protein, alpha 1, 43kDa
GLI2 GLI family zinc finger 2
IDUA iduronidase, alpha-L-
IFT27 intraflagellar transport 27
INHBA inhibin, beta A
IRF6 interferon regulatory factor 6
ITGA11 integrin, alpha 11
KDM4B lysine (K)-specific demethylase 4B
LAMC2 laminin, gamma 2
LEF1 lymphoid enhancer-binding factor 1
LMNA lamin A/C
LPAR1 lysophosphatidic acid receptor 1
LRP4 low density lipoprotein receptor-related protein 4
LRP6 low density lipoprotein receptor-related protein 6
LTBP1 latent transforming growth factor beta binding protein 1
LTBP3 latent transforming growth factor beta binding protein 3
MITF microphthalmia-associated transcription factor
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MSX1 msh homeobox 1
MTF2 metal response element binding transcription factor 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NPR2 natriuretic peptide receptor 2
OSR2 odd-skipped related transciption factor 2
OSTM1 osteopetrosis associated transmembrane protein 1
PAX9 paired box 9
PC pyruvate carboxylase
PITX2 paired-like homeodomain 2
POSTN periostin, osteoblast specific factor
PTCH1 patched 1
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PVRL3 poliovirus receptor-related 3
RUNX2 runt-related transcription factor 2
SATB2 SATB homeobox 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC39A13 solute carrier family 39 (zinc transporter), member 13
SOSTDC1 sclerostin domain containing 1
SP6 Sp6 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY4 sprouty homolog 4 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TBX1 T-box 1
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TGFB1 transforming growth factor, beta 1
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VAX1 ventral anterior homeobox 1
VEGFA vascular endothelial growth factor A
ZIC5 Zic family member 5
ZMPSTE24 zinc metallopeptidase STE24