abnormal immunoglobulin v(d)j recombination Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the process by which immunoglobulin V, D, and J or V and J gene segments, depending on the specific locus, are recombined within a single locus (Mammalian Phenotype Ontology, MP_0008755)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008755
Similar Terms
Downloads & Tools

Genes

13 gene mutations causing the abnormal immunoglobulin v(d)j recombination phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
DCLRE1C DNA cross-link repair 1C
IGKC immunoglobulin kappa constant
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
PAX5 paired box 5
POLB polymerase (DNA directed), beta
POLL polymerase (DNA directed), lambda
POLM polymerase (DNA directed), mu
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
TCF3 transcription factor 3