abnormal heart right ventricle outflow tract morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk (Mammalian Phenotype Ontology, MP_0010428)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010428
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Genes

34 gene mutations causing the abnormal heart right ventricle outflow tract morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADAM17 ADAM metallopeptidase domain 17
ADAM19 ADAM metallopeptidase domain 19
C5ORF42 chromosome 5 open reading frame 42
CC2D2A coiled-coil and C2 domain containing 2A
CXCR4 chemokine (C-X-C motif) receptor 4
DOCK1 dedicator of cytokinesis 1
EFNB2 ephrin-B2
FGFRL1 fibroblast growth factor receptor-like 1
FOXC1 forkhead box C1
FUZ fuzzy planar cell polarity protein
GATA4 GATA binding protein 4
GJA1 gap junction protein, alpha 1, 43kDa
HBEGF heparin-binding EGF-like growth factor
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HHEX hematopoietically expressed homeobox
HOXA3 homeobox A3
HSPG2 heparan sulfate proteoglycan 2
MEGF8 multiple EGF-like-domains 8
MOSPD3 motile sperm domain containing 3
MYH10 myosin, heavy chain 10, non-muscle
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NTF3 neurotrophin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PDLIM3 PDZ and LIM domain 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCE1 phospholipase C, epsilon 1
SMAD6 SMAD family member 6
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB2 transforming growth factor, beta 2
TRIP11 thyroid hormone receptor interactor 11
WDPCP WD repeat containing planar cell polarity effector
ZFPM2 zinc finger protein, FOG family member 2