abnormal heart morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Any structural anomaly of a heart. (Human Phenotype Ontology, HP_3000001)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000266
Similar Terms
Downloads & Tools

Genes

926 gene mutations causing the abnormal heart morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACACB acetyl-CoA carboxylase beta
ACADL acyl-CoA dehydrogenase, long chain
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACADVL acyl-CoA dehydrogenase, very long chain
ACAN aggrecan
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACKR3 atypical chemokine receptor 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTC1 actin, alpha, cardiac muscle 1
ACTN4 actinin, alpha 4
ACVR2B activin A receptor, type IIB
ACVRL1 activin A receptor type II-like 1
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADAM19 ADAM metallopeptidase domain 19
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADGRF5 adhesion G protein-coupled receptor F5
ADGRG6 adhesion G protein-coupled receptor G6
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2A adenosine A2a receptor
ADRA1B adrenoceptor alpha 1B
ADRA2B adrenoceptor alpha 2B
ADRBK1 adrenergic, beta, receptor kinase 1
AGO2 argonaute RISC catalytic component 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIP aryl hydrocarbon receptor interacting protein
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
AMER1 APC membrane recruitment protein 1
ANGPT1 angiopoietin 1
ANK1 ankyrin 1, erythrocytic
ANKRD17 ankyrin repeat domain 17
ANKRD26 ankyrin repeat domain 26
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APH1A APH1A gamma secretase subunit
APLNR apelin receptor
APOE apolipoprotein E
ARID1A AT rich interactive domain 1A (SWI-like)
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL4D ADP-ribosylation factor-like 4D
ARMC4 armadillo repeat containing 4
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSB arylsulfatase B
ASL argininosuccinate lyase
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASXL2 additional sex combs like transcriptional regulator 2
ATE1 arginyltransferase 1
ATMIN ATM interactor
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
ATRX alpha thalassemia/mental retardation syndrome X-linked
AXIN1 axin 1
AXIN2 axin 2
B9D1 B9 protein domain 1
BAG3 BCL2-associated athanogene 3
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBX bobby sox homolog (Drosophila)
BCAR1 breast cancer anti-estrogen resistance 1
BCL6 B-cell CLL/lymphoma 6
BCOR BCL6 corepressor
BICC1 BicC family RNA binding protein 1
BIN1 bridging integrator 1
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BMP10 bone morphogenetic protein 10
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
BVES blood vessel epicardial substance
C1ORF127 chromosome 1 open reading frame 127
C2CD3 C2 calcium-dependent domain containing 3
C5ORF42 chromosome 5 open reading frame 42
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CALCRL calcitonin receptor-like
CALR calreticulin
CAPN2 calpain 2, (m/II) large subunit
CAPNS1 calpain, small subunit 1
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASQ2 calsequestrin 2 (cardiac muscle)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV3 caveolin 3
CBFB core-binding factor, beta subunit
CBS cystathionine-beta-synthase
CBX6 chromobox homolog 6
CC2D2A coiled-coil and C2 domain containing 2A
CCDC151 coiled-coil domain containing 151
CCDC160 coiled-coil domain containing 160
CCDC39 coiled-coil domain containing 39
CCL13 chemokine (C-C motif) ligand 13
CCM2 cerebral cavernous malformation 2
CD28 CD28 molecule
CD2AP CD2-associated protein
CD36 CD36 molecule (thrombospondin receptor)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CENPA centromere protein A
CENPJ centromere protein J
CEP290 centrosomal protein 290kDa
CEP41 centrosomal protein 41kDa
CFC1 cripto, FRL-1, cryptic family 1
CFL1 cofilin 1 (non-muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CHD2 chromodomain helicase DNA binding protein 2
CHD7 chromodomain helicase DNA binding protein 7
CHGA chromogranin A
CHMP5 charged multivesicular body protein 5
CHRD chordin
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CIAPIN1 cytokine induced apoptosis inhibitor 1
CISD2 CDGSH iron sulfur domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKM creatine kinase, muscle
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLEC4E C-type lectin domain family 4, member E
CLU clusterin
CLUAP1 clusterin associated protein 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CNTRL centriolin
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COQ9 coenzyme Q9
CORIN corin, serine peptidase
COX1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CRB2 crumbs family member 2
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRTC1 CREB regulated transcription coactivator 1
CSK c-src tyrosine kinase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSRP2 cysteine and glycine-rich protein 2
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
CTBP2 C-terminal binding protein 2
CTNNA3 catenin (cadherin-associated protein), alpha 3
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYBB cytochrome b-245, beta polypeptide
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAAM1 dishevelled associated activator of morphogenesis 1
DAND5 DAN domain family member 5, BMP antagonist
DAW1 dynein assembly factor with WDR repeat domains 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCHS1 dachsous cadherin-related 1
DCTN5 dynactin 5 (p25)
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DEDD death effector domain containing
DES desmin
DFNB31 deafness, autosomal recessive 31
DHRS3 dehydrogenase/reductase (SDR family) member 3
DISP1 dispatched homolog 1 (Drosophila)
DLC1 DLC1 Rho GTPase activating protein
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DLX3 distal-less homeobox 3
DMD dystrophin
DNAAF2 dynein, axonemal, assembly factor 2
DNAAF3 dynein, axonemal, assembly factor 3
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DNAI1 dynein, axonemal, intermediate chain 1
DNASE1L2 deoxyribonuclease I-like 2
DNM1L dynamin 1-like
DNM2 dynamin 2
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
DOCK1 dedicator of cytokinesis 1
DOT1L DOT1-like histone H3K79 methyltransferase
DRC1 dynein regulatory complex subunit 1
DRD5 dopamine receptor D5
DTNA dystrobrevin, alpha
DUSP6 dual specificity phosphatase 6
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYX1C1 dyslexia susceptibility 1 candidate 1
EAF2 ELL associated factor 2
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EFNA1 ephrin-A1
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR1 early growth response 1
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ELN elastin
EMD emerin
ENG endoglin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA3 EPH receptor A3
EPHB4 EPH receptor B4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPO erythropoietin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV2 ets variant 2
ETV6 ets variant 6
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP3 fatty acid binding protein 3, muscle and heart
FADD Fas (TNFRSF6)-associated via death domain
FAS Fas cell surface death receptor
FAT4 FAT atypical cadherin 4
FBLN1 fibulin 1
FBLN5 fibulin 5
FBN1 fibrillin 1
FBXL5 F-box and leucine-rich repeat protein 5
FBXO11 F-box protein 11
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FENDRR FOXF1 adjacent non-coding developmental regulatory RNA
FES FES proto-oncogene, tyrosine kinase
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF19 fibroblast growth factor 19
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFRL1 fibroblast growth factor receptor-like 1
FHL2 four and a half LIM domains 2
FHOD3 formin homology 2 domain containing 3
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLNA filamin A, alpha
FLRT2 fibronectin leucine rich transmembrane protein 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FOXA2 forkhead box A2
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FOXH1 forkhead box H1
FOXJ1 forkhead box J1
FOXM1 forkhead box M1
FOXO1 forkhead box O1
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FOXP4 forkhead box P4
FREM2 FRAS1 related extracellular matrix protein 2
FRS2 fibroblast growth factor receptor substrate 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
FURIN furin (paired basic amino acid cleaving enzyme)
FUS FUS RNA binding protein
FUZ fuzzy planar cell polarity protein
FXN frataxin
FXR1 fragile X mental retardation, autosomal homolog 1
FXYD1 FXYD domain containing ion transport regulator 1
FZD7 frizzled class receptor 7
G6PD glucose-6-phosphate dehydrogenase
GAA glucosidase, alpha; acid
GAB1 GRB2-associated binding protein 1
GALC galactosylceramidase
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GATA5 GATA binding protein 5
GBE1 glucan (1,4-alpha-), branching enzyme 1
GBX2 gastrulation brain homeobox 2
GDF1 growth differentiation factor 1
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GIPC1 GIPC PDZ domain containing family, member 1
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GJC1 gap junction protein, gamma 1, 45kDa
GLA galactosidase, alpha
GLI3 GLI family zinc finger 3
GLMN glomulin, FKBP associated protein
GLRX3 glutaredoxin 3
GLTSCR1L GLTSCR1-like
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAS GNAS complex locus
GPC3 glypican 3
GPI glucose-6-phosphate isomerase
GPX7 glutathione peroxidase 7
GRB14 growth factor receptor-bound protein 14
GRB2 growth factor receptor-bound protein 2
GRHL2 grainyhead-like 2 (Drosophila)
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D
GRK5 G protein-coupled receptor kinase 5
GSTO2 glutathione S-transferase omega 2
GSTZ1 glutathione S-transferase zeta 1
GTF2I general transcription factor IIi
GTF2IRD1 GTF2I repeat domain containing 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY2C guanylate cyclase 2C
GYS1 glycogen synthase 1 (muscle)
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HAND1 heart and neural crest derivatives expressed 1
HAND2 heart and neural crest derivatives expressed 2
HAS2 hyaluronan synthase 2
HBEGF heparin-binding EGF-like growth factor
HDAC2 histone deacetylase 2
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HDAC9 histone deacetylase 9
HECTD1 HECT domain containing E3 ubiquitin protein ligase 1
HEG1 heart development protein with EGF-like domains 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HFE2 hemochromatosis type 2 (juvenile)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF3A hypoxia inducible factor 3, alpha subunit
HIRA histone cell cycle regulator
HMGA1 high mobility group AT-hook 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HOXA1 homeobox A1
HOXA13 homeobox A13
HOXA3 homeobox A3
HOXB4 homeobox B4
HP1BP3 heterochromatin protein 1, binding protein 3
HPRT1 hypoxanthine phosphoribosyltransferase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPB11 heat shock protein family B (small), member 11
HSPB8 heat shock 22kDa protein 8
HSPG2 heparan sulfate proteoglycan 2
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTRA2 HtrA serine peptidase 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IDUA iduronidase, alpha-L-
IER3 immediate early response 3
IFT122 intraflagellar transport 122
IFT140 intraflagellar transport 140
IFT172 intraflagellar transport 172
IFT27 intraflagellar transport 27
IFT57 intraflagellar transport 57
IFT74 intraflagellar transport 74
IFT88 intraflagellar transport 88
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGHMBP2 immunoglobulin mu binding protein 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL18 interleukin 18
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
INPP5F inositol polyphosphate-5-phosphatase F
INS insulin
INTU inturned planar cell polarity protein
INVS inversin
IRX4 iroquois homeobox 4
ISL1 ISL LIM homeobox 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB8 integrin, beta 8
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAG1 jagged 1
JARID2 jumonji, AT rich interactive domain 2
JMJD6 jumonji domain containing 6
JPH2 junctophilin 2
JUN jun proto-oncogene
JUP junction plakoglobin
KAT6A K(lysine) acetyltransferase 6A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM5C lysine (K)-specific demethylase 5C
KDM6A lysine (K)-specific demethylase 6A
KIAA0586 KIAA0586
KIDINS220 kinase D-interacting substrate, 220kDa
KIF3A kinesin family member 3A
KIF3B kinesin family member 3B
KIF7 kinesin family member 7
KIFAP3 kinesin-associated protein 3
KL klotho
KLF15 Kruppel-like factor 15
KLF3 Kruppel-like factor 3 (basic)
KLF5 Kruppel-like factor 5 (intestinal)
KLK3 kallikrein-related peptidase 3
KMT2B lysine (K)-specific methyltransferase 2B
KRAS Kirsten rat sarcoma viral oncogene homolog
KRIT1 KRIT1, ankyrin repeat containing
LAMA4 laminin, alpha 4
LAMP2 lysosomal-associated membrane protein 2
LARGE like-glycosyltransferase
LASP1 LIM and SH3 protein 1
LATS2 large tumor suppressor kinase 2
LBX1 ladybird homeobox 1
LDB1 LIM domain binding 1
LDB3 LIM domain binding 3
LDHA lactate dehydrogenase A
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LEMD3 LEM domain containing 3
LEP leptin
LEPR leptin receptor
LIAS lipoic acid synthetase
LIN28A lin-28 homolog A (C. elegans)
LMNA lamin A/C
LMO2 LIM domain only 2 (rhombotin-like 1)
LNPEP leucyl/cystinyl aminopeptidase
LOX lysyl oxidase
LPAR4 lysophosphatidic acid receptor 4
LRP1 low density lipoprotein receptor-related protein 1
LRP2 low density lipoprotein receptor-related protein 2
LTA lymphotoxin alpha
LTBP1 latent transforming growth factor beta binding protein 1
LTBP4 latent transforming growth factor beta binding protein 4
LUZP1 leucine zipper protein 1
LY6E lymphocyte antigen 6 complex, locus E
MAB21L2 mab-21-like 2 (C. elegans)
MAP1S microtubule-associated protein 1S
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MARK2 MAP/microtubule affinity-regulating kinase 2
MARVELD2 MARVEL domain containing 2
MB myoglobin
MBD4 methyl-CpG binding domain protein 4
MCOLN1 mucolipin 1
MDM4 MDM4, p53 regulator
MECOM MDS1 and EVI1 complex locus
MED1 mediator complex subunit 1
MED12 mediator complex subunit 12
MED24 mediator complex subunit 24
MED30 mediator complex subunit 30
MEF2A myocyte enhancer factor 2A
MEF2C myocyte enhancer factor 2C
MEGF8 multiple EGF-like-domains 8
MEIS1 Meis homeobox 1
MEN1 multiple endocrine neoplasia I
MEOX2 mesenchyme homeobox 2
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2
MEST mesoderm specific transcript
MFSD8 major facilitator superfamily domain containing 8
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGP matrix Gla protein
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MIB1 mindbomb E3 ubiquitin protein ligase 1
MIR208A microRNA 208a
MIR22 microRNA 22
MIXL1 Mix paired-like homeobox
MKL1 megakaryoblastic leukemia (translocation) 1
MKL2 MKL/myocardin-like 2
MKS1 Meckel syndrome, type 1
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMP2 matrix metallopeptidase 2
MMP21 matrix metallopeptidase 21
MMP9 matrix metallopeptidase 9
MORF4L1 mortality factor 4 like 1
MOSPD3 motile sperm domain containing 3
MPZL3 myelin protein zero-like 3
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MSTN myostatin
MTERF4 mitochondrial transcription termination factor 4
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTMR14 myotubularin related protein 14
MTUS1 microtubule associated tumor suppressor 1
MUS81 MUS81 structure-specific endonuclease subunit
MYBPC3 myosin binding protein C, cardiac
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH10 myosin, heavy chain 10, non-muscle
MYH11 myosin, heavy chain 11, smooth muscle
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL7 myosin, light chain 7, regulatory
MYLK3 myosin light chain kinase 3
MYO18B myosin XVIIIB
MYO6 myosin VI
MYOCD myocardin
MYOZ2 myozenin 2
NACA nascent polypeptide-associated complex alpha subunit
NCF1 neutrophil cytosolic factor 1
NCKAP1 NCK-associated protein 1
NCKAP1L NCK-associated protein 1-like
NCOA6 nuclear receptor coactivator 6
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NCSTN nicastrin
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEK6 NIMA-related kinase 6
NEK8 NIMA-related kinase 8
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NGF nerve growth factor (beta polypeptide)
NIPBL Nipped-B homolog (Drosophila)
NKX2-5 NK2 homeobox 5
NODAL nodal growth differentiation factor
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOV nephroblastoma overexpressed
NOX4 NADPH oxidase 4
NPHP3 nephronophthisis 3 (adolescent)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NPY1R neuropeptide Y receptor Y1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRG1 neuregulin 1
NRP1 neuropilin 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NTF3 neurotrophin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUMB numb homolog (Drosophila)
NUP133 nucleoporin 133kDa
NXN nucleoredoxin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSR1 odd-skipped related transciption factor 1
OTX2 orthodenticle homeobox 2
OVOL2 ovo-like zinc finger 2
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAPPA2 pappalysin 2
PARD3 par-3 family cell polarity regulator
PARVA parvin, alpha
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX3 paired box 3
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PBRM1 polybromo 1
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PDC phosducin
PDCD1 programmed cell death 1
PDCD10 programmed cell death 10
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDLIM3 PDZ and LIM domain 3
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPK1 3-phosphoinositide dependent protein kinase 1
PDPN podoplanin
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PEPD peptidase D
PEX7 peroxisomal biogenesis factor 7
PFKM phosphofructokinase, muscle
PHC1 polyhomeotic homolog 1 (Drosophila)
PHIP pleckstrin homology domain interacting protein
PIFO primary cilia formation
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITX2 paired-like homeodomain 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD1L1 polycystic kidney disease 1 like 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKP2 plakophilin 2
PLA2G15 phospholipase A2, group XV
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAGL1 pleiomorphic adenoma gene-like 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLCE1 phospholipase C, epsilon 1
PLEC plectin
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLIN4 perilipin 4
PLIN5 perilipin 5
PLN phospholamban
PLVAP plasmalemma vesicle associated protein
PLXND1 plexin D1
PMM2 phosphomannomutase 2
PNMT phenylethanolamine N-methyltransferase
PNN pinin, desmosome associated protein
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA6 patatin-like phospholipase domain containing 6
POFUT1 protein O-fucosyltransferase 1
POGLUT1 protein O-glucosyltransferase 1
POLG polymerase (DNA directed), gamma
POPDC2 popeye domain containing 2
POR P450 (cytochrome) oxidoreductase
POSTN periostin, osteoblast specific factor
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM1 PR domain containing 1, with ZNF domain
PRDM16 PR domain containing 16
PRDM6 PR domain containing 6
PRICKLE1 prickle homolog 1 (Drosophila)
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCI protein kinase C, iota
PROKR1 prokineticin receptor 1
PSEN1 presenilin 1
PSKH1 protein serine kinase H1
PTCD2 pentatricopeptide repeat domain 2
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK7 protein tyrosine kinase 7 (inactive)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRJ protein tyrosine phosphatase, receptor type, J
PXN paxillin
QKI QKI, KH domain containing, RNA binding
RAD17 RAD17 homolog (S. pombe)
RAD51D RAD51 paralog D
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASIP1 Ras interacting protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RB1CC1 RB1-inducible coiled-coil 1
RBL2 retinoblastoma-like 2
RBM20 RNA binding motif protein 20
RBP4 retinol binding protein 4, plasma
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RCAN1 regulator of calcineurin 1
RDH10 retinol dehydrogenase 10 (all-trans)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RERE arginine-glutamic acid dipeptide (RE) repeats
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RHEB Ras homolog enriched in brain
RIPPLY3 ripply transcriptional repressor 3
RNF4 ring finger protein 4
RNF7 ring finger protein 7
RNLS renalase, FAD-dependent amine oxidase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPGRIP1L RPGRIP1-like
RPL38 ribosomal protein L38
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPSA ribosomal protein SA
RRAD Ras-related associated with diabetes
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
RSPO3 R-spondin 3
RTEL1 regulator of telomere elongation helicase 1
RTTN rotatin
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
S1PR1 sphingosine-1-phosphate receptor 1
SALL4 spalt-like transcription factor 4
SCG5 secretogranin V
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SEC24B SEC24 family member B
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD2 SET domain containing 2
SFRP1 secreted frizzled-related protein 1
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGPL1 sphingosine-1-phosphate lyase 1
SGSH N-sulfoglucosamine sulfohydrolase
SH3PXD2B SH3 and PX domains 2B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SHOX2 short stature homeobox 2
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SIRT7 sirtuin 7
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC38A10 solute carrier family 38, member 10
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLIT3 slit homolog 3 (Drosophila)
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMN1 survival of motor neuron 1, telomeric
SMO smoothened, frizzled class receptor
SMTN smoothelin
SMYD1 SET and MYND domain containing 1
SNORD50A small nucleolar RNA, C/D box 50A
SNORD50B small nucleolar RNA, C/D box 50B
SNX17 sorting nexin 17
SNX27 sorting nexin family member 27
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOS1 son of sevenless homolog 1 (Drosophila)
SOX11 SRY (sex determining region Y)-box 11
SOX4 SRY (sex determining region Y)-box 4
SOX7 SRY (sex determining region Y)-box 7
SP4 Sp4 transcription factor
SPEG SPEG complex locus
SPEN spen family transcriptional repressor
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPNS1 spinster homolog 1 (Drosophila)
SPP1 secreted phosphoprotein 1
SPTA1 spectrin, alpha, erythrocytic 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SPTB spectrin, beta, erythrocytic
SPTBN1 spectrin, beta, non-erythrocytic 1
SRD5A3 steroid 5 alpha-reductase 3
SRSF10 serine/arginine-rich splicing factor 10
SS18 synovial sarcoma translocation, chromosome 18
SSR1 signal sequence receptor, alpha
STEAP3 STEAP family member 3, metalloreductase
STRAP serine/threonine kinase receptor associated protein
SUFU suppressor of fused homolog (Drosophila)
T T, brachyury homolog (mouse)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAL1 T-cell acute lymphocytic leukemia 1
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBC1D2B TBC1 domain family, member 2B
TBC1D32 TBC1 domain family, member 32
TBC1D4 TBC1 domain family, member 4
TBX1 T-box 1
TBX18 T-box 18
TBX2 T-box 2
TBX20 T-box 20
TBX3 T-box 3
TBX4 T-box 4
TBX5 T-box 5
TBX6 T-box 6
TCAP titin-cap
TCEA1 transcription elongation factor A (SII), 1
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
TCF21 transcription factor 21
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCTN2 tectonic family member 2
TDG thymine-DNA glycosylase
TDGF1 teratocarcinoma-derived growth factor 1
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEK TEK tyrosine kinase, endothelial
TERC telomerase RNA component
TFAM transcription factor A, mitochondrial
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFB1M transcription factor B1, mitochondrial
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TGM2 transglutaminase 2
TH tyrosine hydroxylase
THBD thrombomodulin
THBS1 thrombospondin 1
THBS4 thrombospondin 4
THRA thyroid hormone receptor, alpha
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TIMP3 TIMP metallopeptidase inhibitor 3
TIMP4 TIMP metallopeptidase inhibitor 4
TK2 thymidine kinase 2, mitochondrial
TKT transketolase
TLL1 tolloid-like 1
TLR2 toll-like receptor 2
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM100 transmembrane protein 100
TMEM67 transmembrane protein 67
TMOD1 tropomodulin 1
TMPRSS6 transmembrane protease, serine 6
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TPM1 tropomyosin 1 (alpha)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TREX1 three prime repair exonuclease 1
TRIM54 tripartite motif containing 54
TRIM55 tripartite motif containing 55
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRIP11 thyroid hormone receptor interactor 11
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TSC22D1 TSC22 domain family, member 1
TTBK2 tau tubulin kinase 2
TTC7A tetratricopeptide repeat domain 7A
TTN titin
TXNIP thioredoxin interacting protein
TXNRD2 thioredoxin reductase 2
UBE4B ubiquitination factor E4B
UBP1 upstream binding protein 1 (LBP-1a)
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP8 ubiquitin specific peptidase 8
USP9X ubiquitin specific peptidase 9, X-linked
UTF1 undifferentiated embryonic cell transcription factor 1
VAC14 Vac14 homolog (S. cerevisiae)
VANGL2 VANGL planar cell polarity protein 2
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VCL vinculin
VCP valosin containing protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VIP vasoactive intestinal peptide
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WASF2 WAS protein family, member 2
WASL Wiskott-Aldrich syndrome-like
WDPCP WD repeat containing planar cell polarity effector
WDR35 WD repeat domain 35
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNK1 WNK lysine deficient protein kinase 1
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XIRP1 xin actin binding repeat containing 1
XIRP2 xin actin binding repeat containing 2
XYLB xylulokinase homolog (H. influenzae)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB14 zinc finger and BTB domain containing 14
ZFP36L1 ZFP36 ring finger protein-like 1
ZFPM1 zinc finger protein, FOG family member 1
ZFPM2 zinc finger protein, FOG family member 2
ZIC3 Zic family member 3
ZMIZ1 zinc finger, MIZ-type containing 1
ZMPSTE24 zinc metallopeptidase STE24