abnormal heart atrium morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of one or both of the two upper chambers of the heart, to which the blood returns from the circulation (Mammalian Phenotype Ontology, MP_0003105)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003105
Similar Terms
Downloads & Tools

Genes

150 gene mutations causing the abnormal heart atrium morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACKR3 atypical chemokine receptor 3
ACVR2B activin A receptor, type IIB
ADAM19 ADAM metallopeptidase domain 19
ADRBK1 adrenergic, beta, receptor kinase 1
ANKS6 ankyrin repeat and sterile alpha motif domain containing 6
ATE1 arginyltransferase 1
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BMP4 bone morphogenetic protein 4
BVES blood vessel epicardial substance
C5ORF42 chromosome 5 open reading frame 42
CASQ2 calsequestrin 2 (cardiac muscle)
CC2D2A coiled-coil and C2 domain containing 2A
CCDC39 coiled-coil domain containing 39
CEP290 centrosomal protein 290kDa
CFC1 cripto, FRL-1, cryptic family 1
CHD2 chromodomain helicase DNA binding protein 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNTRL centriolin
CREBBP CREB binding protein
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAND5 DAN domain family member 5, BMP antagonist
DCHS1 dachsous cadherin-related 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLC1 DLC1 Rho GTPase activating protein
DLL4 delta-like 4 (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DNAH5 dynein, axonemal, heavy chain 5
DRC1 dynein regulatory complex subunit 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYX1C1 dyslexia susceptibility 1 candidate 1
EGLN1 egl-9 family hypoxia-inducible factor 1
EP300 E1A binding protein p300
EPHA3 EPH receptor A3
FAT4 FAT atypical cadherin 4
FBLN1 fibulin 1
FBN1 fibrillin 1
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF19 fibroblast growth factor 19
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP1A FK506 binding protein 1A, 12kDa
FLNA filamin A, alpha
FREM2 FRAS1 related extracellular matrix protein 2
GATA4 GATA binding protein 4
GATA5 GATA binding protein 5
GDF1 growth differentiation factor 1
GJA1 gap junction protein, alpha 1, 43kDa
GJA5 gap junction protein, alpha 5, 40kDa
GYS1 glycogen synthase 1 (muscle)
HAS2 hyaluronan synthase 2
HDAC7 histone deacetylase 7
HEG1 heart development protein with EGF-like domains 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIF3A hypoxia inducible factor 3, alpha subunit
HRAS Harvey rat sarcoma viral oncogene homolog
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IFT172 intraflagellar transport 172
IFT27 intraflagellar transport 27
IFT74 intraflagellar transport 74
IFT88 intraflagellar transport 88
IGHMBP2 immunoglobulin mu binding protein 2
INVS inversin
IRX4 iroquois homeobox 4
ISL1 ISL LIM homeobox 1
JARID2 jumonji, AT rich interactive domain 2
JUP junction plakoglobin
KAT6A K(lysine) acetyltransferase 6A
KIDINS220 kinase D-interacting substrate, 220kDa
KIFAP3 kinesin-associated protein 3
KLF3 Kruppel-like factor 3 (basic)
LATS2 large tumor suppressor kinase 2
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LMNA lamin A/C
LTBP1 latent transforming growth factor beta binding protein 1
LY6E lymphocyte antigen 6 complex, locus E
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MEF2C myocyte enhancer factor 2C
MEGF8 multiple EGF-like-domains 8
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MKL1 megakaryoblastic leukemia (translocation) 1
MYBPC3 myosin binding protein C, cardiac
MYH10 myosin, heavy chain 10, non-muscle
MYH6 myosin, heavy chain 6, cardiac muscle, alpha
MYL7 myosin, light chain 7, regulatory
MYO18B myosin XVIIIB
MYOZ2 myozenin 2
NIPBL Nipped-B homolog (Drosophila)
NKX2-5 NK2 homeobox 5
NODAL nodal growth differentiation factor
NOS3 nitric oxide synthase 3 (endothelial cell)
NRP1 neuropilin 1
NTF3 neurotrophin 3
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OSR1 odd-skipped related transciption factor 1
PARD3 par-3 family cell polarity regulator
PCSK5 proprotein convertase subtilisin/kexin type 5
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PIKFYVE phosphoinositide kinase, FYVE finger containing
PITX2 paired-like homeodomain 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKP2 plakophilin 2
PLAGL1 pleiomorphic adenoma gene-like 1
PLXND1 plexin D1
POPDC2 popeye domain containing 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RXRA retinoid X receptor, alpha
RYR1 ryanodine receptor 1 (skeletal)
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SHH sonic hedgehog
SHOX2 short stature homeobox 2
SIRT1 sirtuin 1
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPEG SPEG complex locus
SRSF10 serine/arginine-rich splicing factor 10
TBC1D32 TBC1 domain family, member 32
TBX20 T-box 20
TBX3 T-box 3
TBX5 T-box 5
TCF21 transcription factor 21
TGFB2 transforming growth factor, beta 2
TH tyrosine hydroxylase
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TLL1 tolloid-like 1
TTN titin
VAC14 Vac14 homolog (S. cerevisiae)
VCAN versican
WHSC1 Wolf-Hirschhorn syndrome candidate 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFPM2 zinc finger protein, FOG family member 2
ZIC3 Zic family member 3
ZMIZ1 zinc finger, MIZ-type containing 1