abnormal granulosa cell morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of a supporting cell for the developing female gamete in the ovary of mammals; granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle (Mammalian Phenotype Ontology, MP_0008868)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008868
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Genes

20 gene mutations causing the abnormal granulosa cell morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CSF1 colony stimulating factor 1 (macrophage)
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FADS2 fatty acid desaturase 2
FSHR follicle stimulating hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
NPC1 Niemann-Pick disease, type C1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
TBPL2 TATA box binding protein like 2
ZP1 zona pellucida glycoprotein 1 (sperm receptor)
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)