abnormal folic acid level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the concentration of the vitamin B family member that stimulates the hematopoietic system, is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses, and is used in the treatment and prevention of folate deficiencies and megaloblastic anemia (Mammalian Phenotype Ontology, MP_0011230)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011230
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Genes

3 gene mutations causing the abnormal folic acid level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
FOLR1 folate receptor 1 (adult)
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)