abnormal fear-related response Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description altered emotional response related to anticipation of specific pain or danger (Mammalian Phenotype Ontology, MP_0003106)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003106
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Genes

40 gene mutations causing the abnormal fear-related response phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADRA1B adrenoceptor alpha 1B
AGTR2 angiotensin II receptor, type 2
APP amyloid beta (A4) precursor protein
ARC activity-regulated cytoskeleton-associated protein
ARSG arylsulfatase G
ARX aristaless related homeobox
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
ESR1 estrogen receptor 1
FMR1 fragile X mental retardation 1
FXR2 fragile X mental retardation, autosomal homolog 2
FYN FYN proto-oncogene, Src family tyrosine kinase
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GM2A GM2 ganglioside activator
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GTF2IRD1 GTF2I repeat domain containing 1
IFNG interferon, gamma
IL6 interleukin 6
KALRN kalirin, RhoGEF kinase
LYPD1 LY6/PLAUR domain containing 1
MAOA monoamine oxidase A
MAP2 microtubule-associated protein 2
MECP2 methyl CpG binding protein 2
NAGLU N-acetylglucosaminidase, alpha
NR4A2 nuclear receptor subfamily 4, group A, member 2
OTC ornithine carbamoyltransferase
PTCH1 patched 1
RYR3 ryanodine receptor 3
SLITRK1 SLIT and NTRK-like family, member 1
SP4 Sp4 transcription factor
TACR3 tachykinin receptor 3
TLR3 toll-like receptor 3
TNC tenascin C
TRPC5 transient receptor potential cation channel, subfamily C, member 5
UBR1 ubiquitin protein ligase E3 component n-recognin 1