abnormal endocrine pancreas development Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the formation of the smaller portion of the pancreas that secretes a number of hormones into the blood stream that are produced by the cells in the islets of Langerhans (Mammalian Phenotype Ontology, MP_0011932)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011932
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Genes

12 gene mutations causing the abnormal endocrine pancreas development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
GDF11 growth differentiation factor 11
ILDR2 immunoglobulin-like domain containing receptor 2
INSM1 insulinoma-associated 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NKX2-2 NK2 homeobox 2
PAX6 paired box 6
PCSK2 proprotein convertase subtilisin/kexin type 2
PDX1 pancreatic and duodenal homeobox 1
SEC23B Sec23 homolog B (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
TLE3 transducin-like enhancer of split 3