abnormal double-strand dna break repair Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix (Mammalian Phenotype Ontology, MP_0010948)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010948
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Genes

30 gene mutations causing the abnormal double-strand dna break repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CENPJ centromere protein J
CUL4A cullin 4A
EXO1 exonuclease 1
GGN gametogenetin
HORMAD1 HORMA domain containing 1
IP6K2 inositol hexakisphosphate kinase 2
M1AP meiosis 1 associated protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MCM8 minichromosome maintenance complex component 8
MDC1 mediator of DNA-damage checkpoint 1
MEIOB meiosis specific with OB domains
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PRDM9 PR domain containing 9
RAD21L1 RAD21-like 1 (S. pombe)
RIF1 replication timing regulatory factor 1
SOD2 superoxide dismutase 2, mitochondrial
SPATA22 spermatogenesis associated 22
SPO11 SPO11 meiotic protein covalently bound to DSB
STIP1 stress-induced phosphoprotein 1
SYCE1 synaptonemal complex central element protein 1
TDRKH tudor and KH domain containing
TET1 tet methylcytosine dioxygenase 1
TEX15 testis expressed 15
TRIP13 thyroid hormone receptor interactor 13
UBE2B ubiquitin-conjugating enzyme E2B
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZC3HC1 zinc finger, C3HC-type containing 1