abnormal dna replication Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the process whereby new strands of DNA are synthesized (Mammalian Phenotype Ontology, MP_0008057)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008057
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Genes

17 gene mutations causing the abnormal dna replication phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATR ATR serine/threonine kinase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CUL4A cullin 4A
DICER1 dicer 1, ribonuclease type III
FEN1 flap structure-specific endonuclease 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
LIG1 ligase I, DNA, ATP-dependent
LMNA lamin A/C
MCM8 minichromosome maintenance complex component 8
MCM9 minichromosome maintenance complex component 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PIKFYVE phosphoinositide kinase, FYVE finger containing
PURA purine-rich element binding protein A
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RTEL1 regulator of telomere elongation helicase 1
SIRT1 sirtuin 1
TP53 tumor protein p53