abnormal cortical plate morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers (Mammalian Phenotype Ontology, MP_0008439)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008439
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Genes

19 gene mutations causing the abnormal cortical plate morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ARX aristaless related homeobox
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
FBXO45 F-box protein 45
IL6ST interleukin 6 signal transducer
ITGA6 integrin, alpha 6
KAT6B K(lysine) acetyltransferase 6B
LAMC1 laminin, gamma 1 (formerly LAMB2)
LEP leptin
LHX2 LIM homeobox 2
LMNB2 lamin B2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MCPH1 microcephalin 1
PAX6 paired box 6
PSEN1 presenilin 1
TOP2B topoisomerase (DNA) II beta 180kDa
TP53BP2 tumor protein p53 binding protein 2
TUBB2B tubulin, beta 2B class IIb
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2