abnormal common carotid artery morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the left or right common carotid arteries which extend headward on each side of the anterior neck and deliver oxygenated nutrient filled blood from the heart to the head, neck and brain; the left originates in the arch of the aorta over the heart; the right originates in the brachiocephalic trunk, the largest branch from the arch of the aorta; each common carotid artery divides into an external and an internal carotid artery (Mammalian Phenotype Ontology, MP_0012729)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0012729
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Genes

10 gene mutations causing the abnormal common carotid artery morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
CHD7 chromodomain helicase DNA binding protein 7
CHRD chordin
CRK v-crk avian sarcoma virus CT10 oncogene homolog
FBLN1 fibulin 1
MKL2 MKL/myocardin-like 2
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PAX3 paired box 3
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SIX1 SIX homeobox 1