abnormal circulating interleukin-5 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the amount in the blood of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells (Mammalian Phenotype Ontology, MP_0008625)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008625
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Genes

9 gene mutations causing the abnormal circulating interleukin-5 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CARD11 caspase recruitment domain family, member 11
FOXP3 forkhead box P3
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
IL13RA1 interleukin 13 receptor, alpha 1
IL5 interleukin 5
IRF1 interferon regulatory factor 1
NLRP3 NLR family, pyrin domain containing 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TP53 tumor protein p53