abnormal chemokine secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the production or cellular release of any of the class of pro-inflammatory cytokines that attract and activate leukocytes (Mammalian Phenotype Ontology, MP_0008722)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008722
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Genes

47 gene mutations causing the abnormal chemokine secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
CARD9 caspase recruitment domain family, member 9
CCL13 chemokine (C-C motif) ligand 13
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CD274 CD274 molecule
CD300A CD300a molecule
CD44 CD44 molecule (Indian blood group)
CLEC4D C-type lectin domain family 4, member D
CLEC4E C-type lectin domain family 4, member E
CLEC6A C-type lectin domain family 6, member A
CLIC4 chloride intracellular channel 4
DUSP1 dual specificity phosphatase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FASTK Fas-activated serine/threonine kinase
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
GPR34 G protein-coupled receptor 34
GRN granulin
HSPB1 heat shock 27kDa protein 1
IDO2 indoleamine 2,3-dioxygenase 2
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL17RB interleukin 17 receptor B
IRAK4 interleukin-1 receptor-associated kinase 4
LEP leptin
LEPR leptin receptor
MMP28 matrix metallopeptidase 28
MYD88 myeloid differentiation primary response 88
NOD1 nucleotide-binding oligomerization domain containing 1
PGLYRP1 peptidoglycan recognition protein 1
PGLYRP2 peptidoglycan recognition protein 2
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PTPRC protein tyrosine phosphatase, receptor type, C
RAG2 recombination activating gene 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SELPLG selectin P ligand
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZC3H12A zinc finger CCCH-type containing 12A