abnormal chemokine level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description deviation from the normal levels of any of the class of pro-inflammatory cytokines that attract and activate leukocytes (Mammalian Phenotype Ontology, MP_0008721)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008721
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Genes

49 gene mutations causing the abnormal chemokine level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR4 atypical chemokine receptor 4
ADAM17 ADAM metallopeptidase domain 17
AHR aryl hydrocarbon receptor
AIRE autoimmune regulator
BCL6 B-cell CLL/lymphoma 6
CAV1 caveolin 1, caveolae protein, 22kDa
CCL13 chemokine (C-C motif) ligand 13
CCR1 chemokine (C-C motif) receptor 1
CD36 CD36 molecule (thrombospondin receptor)
CD44 CD44 molecule (Indian blood group)
CLCA1 chloride channel accessory 1
CPB2 carboxypeptidase B2 (plasma)
CTSC cathepsin C
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR2 chemokine (C-X-C motif) receptor 2
DUSP1 dual specificity phosphatase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FOXP3 forkhead box P3
FYN FYN proto-oncogene, Src family tyrosine kinase
GPR21 G protein-coupled receptor 21
HRH4 histamine receptor H4
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
IL13 interleukin 13
IL17RC interleukin 17 receptor C
ING4 inhibitor of growth family, member 4
IRAK2 interleukin-1 receptor-associated kinase 2
LBP lipopolysaccharide binding protein
LEPR leptin receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MEP1A meprin A, alpha (PABA peptide hydrolase)
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MYD88 myeloid differentiation primary response 88
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
PGLYRP2 peptidoglycan recognition protein 2
PILRB paired immunoglobin-like type 2 receptor beta
PTGDR2 prostaglandin D2 receptor 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SELK selenoprotein K
SFTPD surfactant protein D
SPP1 secreted phosphoprotein 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
ZC3H12A zinc finger CCCH-type containing 12A
ZFPM1 zinc finger protein, FOG family member 1