abnormal cd8-positive, alpha-beta t cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description atypical production of or inability to produce the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions (Mammalian Phenotype Ontology, MP_0008080)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008080
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Genes

13 gene mutations causing the abnormal cd8-positive, alpha-beta t cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD8A CD8a molecule
CD8B CD8b molecule
DOCK2 dedicator of cytokinesis 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
IL15 interleukin 15
ITK IL2-inducible T-cell kinase
LCK LCK proto-oncogene, Src family tyrosine kinase
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
RUNX3 runt-related transcription factor 3
SASH3 SAM and SH3 domain containing 3
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZNF335 zinc finger protein 335