abnormal base-excision repair Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any anomaly in the process whereby an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate; the small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase (Mammalian Phenotype Ontology, MP_0009796)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009796
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7 gene mutations causing the abnormal base-excision repair phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATMIN ATM interactor
GADD45A growth arrest and DNA-damage-inducible, alpha
POLB polymerase (DNA directed), beta
POLL polymerase (DNA directed), lambda
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
UNG uracil-DNA glycosylase
XPA xeroderma pigmentosum, complementation group A