abnormal artery development Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomaly in the process of forming the blood vessels that carry blood away from the heart (Mammalian Phenotype Ontology, MP_0003410)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003410
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Genes

102 gene mutations causing the abnormal artery development phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABRA actin binding Rho activating protein
ACVRL1 activin A receptor type II-like 1
ADM adrenomedullin
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ATF2 activating transcription factor 2
BMP5 bone morphogenetic protein 5
CCM2 cerebral cavernous malformation 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CHD7 chromodomain helicase DNA binding protein 7
CHRD chordin
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DLL4 delta-like 4 (Drosophila)
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EFNB2 ephrin-B2
ELN elastin
ENG endoglin
ETV2 ets variant 2
FGF8 fibroblast growth factor 8 (androgen-induced)
FLNB filamin B, beta
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOXC1 forkhead box C1
FOXC2 forkhead box C2
FOXH1 forkhead box H1
FOXO1 forkhead box O1
GBX2 gastrulation brain homeobox 2
HAND2 heart and neural crest derivatives expressed 2
HDAC7 histone deacetylase 7
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXA13 homeobox A13
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ISL1 ISL LIM homeobox 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KAT6A K(lysine) acetyltransferase 6A
KAT7 K(lysine) acetyltransferase 7
KDR kinase insert domain receptor
KRIT1 KRIT1, ankyrin repeat containing
LEMD3 LEM domain containing 3
LMO2 LIM domain only 2 (rhombotin-like 1)
LTBP1 latent transforming growth factor beta binding protein 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK7 mitogen-activated protein kinase 7
MED24 mediator complex subunit 24
MEF2C myocyte enhancer factor 2C
MIB1 mindbomb E3 ubiquitin protein ligase 1
MKL2 MKL/myocardin-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYOCD myocardin
NGFR nerve growth factor receptor
NKX2-5 NK2 homeobox 5
NOTCH1 notch 1
NOTCH3 notch 3
NRP1 neuropilin 1
PAX3 paired box 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PITX2 paired-like homeodomain 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLXND1 plexin D1
PNPLA6 patatin-like phospholipase domain containing 6
POGLUT1 protein O-glucosyltransferase 1
PRDM1 PR domain containing 1, with ZNF domain
PTK2 protein tyrosine kinase 2
PTPRJ protein tyrosine phosphatase, receptor type, J
PXN paxillin
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RASIP1 Ras interacting protein 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RDH10 retinol dehydrogenase 10 (all-trans)
RIPPLY3 ripply transcriptional repressor 3
RXRA retinoid X receptor, alpha
SCX scleraxis basic helix-loop-helix transcription factor
SMAD2 SMAD family member 2
SMAD5 SMAD family member 5
SMAD7 SMAD family member 7
SOX4 SRY (sex determining region Y)-box 4
STK11 serine/threonine kinase 11
T T, brachyury homolog (mouse)
TAL1 T-cell acute lymphocytic leukemia 1
TBX1 T-box 1
TBX2 T-box 2
TBX4 T-box 4
TBX6 T-box 6
TDG thymine-DNA glycosylase
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFB2 transforming growth factor, beta 2
TLL1 tolloid-like 1
TMEM100 transmembrane protein 100
TTN titin
VEGFA vascular endothelial growth factor A
VEZF1 vascular endothelial zinc finger 1
WASF2 WAS protein family, member 2
WNK1 WNK lysine deficient protein kinase 1
ZFP36L1 ZFP36 ring finger protein-like 1
ZMIZ1 zinc finger, MIZ-type containing 1