abnormal alveolar macrophage morphology Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description any structural anomaly of the round, granular, mononuclear phagocytes found in the alveoli of the lungs which ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells (Mammalian Phenotype Ontology, MP_0008245)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008245
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Genes

10 gene mutations causing the abnormal alveolar macrophage morphology phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
CMKLR1 chemerin chemokine-like receptor 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
HCK HCK proto-oncogene, Src family tyrosine kinase
HOXA5 homeobox A5
LIPA lipase A, lysosomal acid, cholesterol esterase
LYZ lysozyme
NPC1 Niemann-Pick disease, type C1
NPC2 Niemann-Pick disease, type C2
SFTPD surfactant protein D