abnormal airway responsiveness Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description anomalous response in bronchial provocation tests (Mammalian Phenotype Ontology, MP_0002334)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002334
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Genes

43 gene mutations causing the abnormal airway responsiveness phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADORA3 adenosine A3 receptor
AQP5 aquaporin 5
C3AR1 complement component 3a receptor 1
C5 complement component 5
CALCB calcitonin-related polypeptide beta
CARD11 caspase recruitment domain family, member 11
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
CXCR2 chemokine (C-X-C motif) receptor 2
FAS Fas cell surface death receptor
GRK5 G protein-coupled receptor kinase 5
ICAM2 intercellular adhesion molecule 2
IFNG interferon, gamma
IL10 interleukin 10
IL13RA1 interleukin 13 receptor, alpha 1
IL17RB interleukin 17 receptor B
IL33 interleukin 33
IL4 interleukin 4
IL4R interleukin 4 receptor
IL5 interleukin 5
ITGA9 integrin, alpha 9
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LPAR2 lysophosphatidic acid receptor 2
LTB4R leukotriene B4 receptor
MINA MYC induced nuclear antigen
MYD88 myeloid differentiation primary response 88
NGFR nerve growth factor receptor
PRKCQ protein kinase C, theta
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RUNX3 runt-related transcription factor 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SPRED1 sprouty-related, EVH1 domain containing 1
SSTR4 somatostatin receptor 4
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TACR1 tachykinin receptor 1
TBX21 T-box 21
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TSLP thymic stromal lymphopoietin