abnormal aggression-related behavior Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description domineering, assaultive or forceful physical action (Mammalian Phenotype Ontology, MP_0002061)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002061
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Genes

75 gene mutations causing the abnormal aggression-related behavior phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADORA2A adenosine A2a receptor
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARX aristaless related homeobox
AVPR1B arginine vasopressin receptor 1B
BBS1 Bardet-Biedl syndrome 1
BBS2 Bardet-Biedl syndrome 2
BBS4 Bardet-Biedl syndrome 4
BDNF brain-derived neurotrophic factor
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DRD2 dopamine receptor D2
DST dystonin
EGR1 early growth response 1
EN2 engrailed homeobox 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FEV FEV (ETS oncogene family)
FMR1 fragile X mental retardation 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GDI1 GDP dissociation inhibitor 1
GIF gastric intrinsic factor (vitamin B synthesis)
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRN granulin
GTF2IRD1 GTF2I repeat domain containing 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTT huntingtin
HYDIN HYDIN, axonemal central pair apparatus protein
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IL6 interleukin 6
KIRREL3 kin of IRRE like 3 (Drosophila)
LAMA2 laminin, alpha 2
LRRC7 leucine rich repeat containing 7
LRTOMT leucine rich transmembrane and O-methyltransferase domain containing
LSAMP limbic system-associated membrane protein
MAOA monoamine oxidase A
MAP6 microtubule-associated protein 6
MC5R melanocortin 5 receptor
MKKS McKusick-Kaufman syndrome
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NOS1 nitric oxide synthase 1 (neuronal)
NPY1R neuropeptide Y receptor Y1
NPY4R neuropeptide Y receptor Y4
NR2E1 nuclear receptor subfamily 2, group E, member 1
NT5E 5'-nucleotidase, ecto (CD73)
OPHN1 oligophrenin 1
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
POMC proopiomelanocortin
PPT1 palmitoyl-protein thioesterase 1
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
RGS4 regulator of G-protein signaling 4
RORB RAR-related orphan receptor B
SHANK3 SH3 and multiple ankyrin repeat domains 3
SYN1 synapsin I
SYN2 synapsin II
SYN3 synapsin III
TACR1 tachykinin receptor 1
TP73 tumor protein p73
TPGS1 tubulin polyglutamylase complex subunit 1
TPH2 tryptophan hydroxylase 2
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSN translin
ZEB1 zinc finger E-box binding homeobox 1
ZIC2 Zic family member 2