abamectin-7218 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the abamectin-7218 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADARB1 adenosine deaminase, RNA-specific, B1
AIM1L absent in melanoma 1-like
APC adenomatous polyposis coli
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATAT1 alpha tubulin acetyltransferase 1
AVPR1B arginine vasopressin receptor 1B
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST10 carbohydrate sulfotransferase 10
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL10A1 collagen, type X, alpha 1
CPD carboxypeptidase D
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPY19L1 dpy-19-like 1 (C. elegans)
DRD2 dopamine receptor D2
DSC2 desmocollin 2
DTNA dystrobrevin, alpha
DUSP1 dual specificity phosphatase 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EZR ezrin
FGF18 fibroblast growth factor 18
FKBP10 FK506 binding protein 10, 65 kDa
FLT3LG fms-related tyrosine kinase 3 ligand
FUS FUS RNA binding protein
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GRB10 growth factor receptor-bound protein 10
GRM8 glutamate receptor, metabotropic 8
HDLBP high density lipoprotein binding protein
HOXB3 homeobox B3
HOXD9 homeobox D9
ICAM1 intercellular adhesion molecule 1
IGFBP5 insulin-like growth factor binding protein 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INHBE inhibin, beta E
KIAA0087 KIAA0087
KLF9 Kruppel-like factor 9
KLHL22 kelch-like family member 22
KLHL28 kelch-like family member 28
LAPTM5 lysosomal protein transmembrane 5
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MATN3 matrilin 3
MST1 macrophage stimulating 1
MTA1 metastasis associated 1
NCAPH2 non-SMC condensin II complex, subunit H2
NCR2 natural cytotoxicity triggering receptor 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NLE1 notchless homolog 1 (Drosophila)
NOL12 nucleolar protein 12
NUPR1 nuclear protein, transcriptional regulator, 1
OCA2 oculocutaneous albinism II
PAX3 paired box 3
PCDHB17P protocadherin beta 17 pseudogene
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PRF1 perforin 1 (pore forming protein)
PSG1 pregnancy specific beta-1-glycoprotein 1
PTCRA pre T-cell antigen receptor alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RBBP9 retinoblastoma binding protein 9
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS9 regulator of G-protein signaling 9
SEC14L5 SEC14-like 5 (S. cerevisiae)
SH3GL3 SH3-domain GRB2-like 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOS2 son of sevenless homolog 2 (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
STC1 stanniocalcin 1
SYNJ1 synaptojanin 1
TCF3 transcription factor 3
TCP10 t-complex 10
TEX40 testis expressed 40
TLR2 toll-like receptor 2
TMPRSS2 transmembrane protease, serine 2
TXNIP thioredoxin interacting protein
USP34 ubiquitin specific peptidase 34
VEGFA vascular endothelial growth factor A
VIPR1 vasoactive intestinal peptide receptor 1
VPRBP Vpr (HIV-1) binding protein
YY2 YY2 transcription factor
ZNF277 zinc finger protein 277

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADGRA3 adhesion G protein-coupled receptor A3
ADGRE5 adhesion G protein-coupled receptor E5
ALDOC aldolase C, fructose-bisphosphate
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF132 chromosome 14 open reading frame 132
C7ORF43 chromosome 7 open reading frame 43
C9ORF40 chromosome 9 open reading frame 40
CBX7 chromobox homolog 7
CCDC88C coiled-coil domain containing 88C
CD302 CD302 molecule
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CLDN15 claudin 15
CXORF56 chromosome X open reading frame 56
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAL4 dynein, axonemal, light chain 4
DOCK1 dedicator of cytokinesis 1
DSN1 DSN1, MIS12 kinetochore complex component
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
EYA2 EYA transcriptional coactivator and phosphatase 2
FA2H fatty acid 2-hydroxylase
FAM178A family with sequence similarity 178, member A
FAM192A family with sequence similarity 192, member A
FBXW12 F-box and WD repeat domain containing 12
FLCN folliculin
GAN gigaxonin
GATA6 GATA binding protein 6
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GHR growth hormone receptor
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HCFC2 host cell factor C2
HPSE heparanase
IRAK4 interleukin-1 receptor-associated kinase 4
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KRT13 keratin 13, type I
LOC100287590 uncharacterized LOC100287590
LOC642236 FSHD region gene 1 pseudogene
LOC730101 uncharacterized LOC730101
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP5 low density lipoprotein receptor-related protein 5
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
NBEAL2 neurobeachin-like 2
NCAM2 neural cell adhesion molecule 2
NCSTN nicastrin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NKAIN1 Na+/K+ transporting ATPase interacting 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRSN2 neurensin 2
NUP62CL nucleoporin 62kDa C-terminal like
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PEX11A peroxisomal biogenesis factor 11 alpha
PLD2 phospholipase D2
PLIN3 perilipin 3
PP14571 uncharacterized LOC100130449
PTDSS2 phosphatidylserine synthase 2
QTRT1 queuine tRNA-ribosyltransferase 1
RAB23 RAB23, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFX7 regulatory factor X, 7
ROM1 retinal outer segment membrane protein 1
RWDD3 RWD domain containing 3
SALL2 spalt-like transcription factor 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SPINK4 serine peptidase inhibitor, Kazal type 4
STK16 serine/threonine kinase 16
STXBP1 syntaxin binding protein 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM254 transmembrane protein 254
TMEM62 transmembrane protein 62
TMUB2 transmembrane and ubiquitin-like domain containing 2
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR6 WD repeat domain 6
WWC2 WW and C2 domain containing 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB3 zinc finger and BTB domain containing 3
ZMYM1 zinc finger, MYM-type 1
ZNF226 zinc finger protein 226
ZNF253 zinc finger protein 253
ZNF276 zinc finger protein 276
ZNF35 zinc finger protein 35
ZNF430 zinc finger protein 430
ZNF573 zinc finger protein 573
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF767P zinc finger family member 767, pseudogene
ZNF85 zinc finger protein 85