abamectin-2519 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the abamectin-2519 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX1 acyl-CoA oxidase 1, palmitoyl
ADAM22 ADAM metallopeptidase domain 22
ADRA2C adrenoceptor alpha 2C
ANGPTL2 angiopoietin-like 2
AOAH acyloxyacyl hydrolase (neutrophil)
ARHGAP35 Rho GTPase activating protein 35
ARID1A AT rich interactive domain 1A (SWI-like)
ARMCX4 armadillo repeat containing, X-linked 4
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BEST2 bestrophin 2
BMP8B bone morphogenetic protein 8b
C21ORF62 chromosome 21 open reading frame 62
C8A complement component 8, alpha polypeptide
CD163 CD163 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
CENPO centromere protein O
CLCN4 chloride channel, voltage-sensitive 4
DFNA5 deafness, autosomal dominant 5
DUOX1 dual oxidase 1
DUSP1 dual specificity phosphatase 1
E2F5 E2F transcription factor 5, p130-binding
ELN elastin
FN1 fibronectin 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXP3 forkhead box P3
FRMD8 FERM domain containing 8
FUS FUS RNA binding protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGLV3-19 immunoglobulin lambda variable 3-19
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCC IQ motif containing C
ITGB5 integrin, beta 5
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIAA1109 KIAA1109
KLHDC8A kelch domain containing 8A
KRIT1 KRIT1, ankyrin repeat containing
KRT32 keratin 32, type I
KYNU kynureninase
LAMA4 laminin, alpha 4
LPAR1 lysophosphatidic acid receptor 1
LPAR3 lysophosphatidic acid receptor 3
MANSC1 MANSC domain containing 1
MAPK7 mitogen-activated protein kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2C myocyte enhancer factor 2C
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MPL MPL proto-oncogene, thrombopoietin receptor
MTMR7 myotubularin related protein 7
MUC1 mucin 1, cell surface associated
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NCOA3 nuclear receptor coactivator 3
NCOR2 nuclear receptor corepressor 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NPAS2 neuronal PAS domain protein 2
NPHP1 nephronophthisis 1 (juvenile)
NRP1 neuropilin 1
PLSCR3 phospholipid scramblase 3
POFUT1 protein O-fucosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRO2964 uncharacterized protein PRO2964
PRSS53 protease, serine, 53
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTRF polymerase I and transcript release factor
RAP1GAP RAP1 GTPase activating protein
RAP1GAP2 RAP1 GTPase activating protein 2
RASAL2 RAS protein activator like 2
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROM1 retinal outer segment membrane protein 1
RTN1 reticulon 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SIRT5 sirtuin 5
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRPK3 SRSF protein kinase 3
STRA6 stimulated by retinoic acid 6
STS steroid sulfatase (microsomal), isozyme S
UPK2 uroplakin 2
USH1C Usher syndrome 1C (autosomal recessive, severe)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZER1 zyg-11 related, cell cycle regulator
ZNF235 zinc finger protein 235
ZNF286A zinc finger protein 286A
ZNF771 zinc finger protein 771
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AMDHD2 amidohydrolase domain containing 2
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOH apolipoprotein H (beta-2-glycoprotein I)
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARG1 arginase 1
ATAT1 alpha tubulin acetyltransferase 1
AXIN1 axin 1
BHLHE41 basic helix-loop-helix family, member e41
C16ORF59 chromosome 16 open reading frame 59
C1ORF56 chromosome 1 open reading frame 56
CD300C CD300c molecule
CD69 CD69 molecule
CDON cell adhesion associated, oncogene regulated
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCF1 cardiotrophin-like cytokine factor 1
COL19A1 collagen, type XIX, alpha 1
CPNE7 copine VII
CPTP ceramide-1-phosphate transfer protein
CRELD1 cysteine-rich with EGF-like domains 1
CROT carnitine O-octanoyltransferase
CTC1 CTS telomere maintenance complex component 1
CTSD cathepsin D
CXORF56 chromosome X open reading frame 56
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
DOK3 docking protein 3
DYM dymeclin
EFNA3 ephrin-A3
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
FAM102A family with sequence similarity 102, member A
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FKBP14 FK506 binding protein 14, 22 kDa
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRA1 glycine receptor, alpha 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPRC5C G protein-coupled receptor, class C, group 5, member C
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HCG4 HLA complex group 4 (non-protein coding)
HIST1H2BI histone cluster 1, H2bi
HOXA5 homeobox A5
HS1BP3 HCLS1 binding protein 3
INF2 inverted formin, FH2 and WH2 domain containing
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0754 KIAA0754
KLHL21 kelch-like family member 21
KLHL36 kelch-like family member 36
LATS1 large tumor suppressor kinase 1
LOC257152 uncharacterized LOC257152
LTBP3 latent transforming growth factor beta binding protein 3
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MGP matrix Gla protein
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MYO1E myosin IE
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NOD1 nucleotide-binding oligomerization domain containing 1
NXF2 nuclear RNA export factor 2
OLAH oleoyl-ACP hydrolase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OXTR oxytocin receptor
PADI2 peptidyl arginine deiminase, type II
PENK proenkephalin
PHOX2A paired-like homeobox 2a
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PODNL1 podocan-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF122 ring finger protein 122
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SERINC5 serine incorporator 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SMYD5 SMYD family member 5
STAT5A signal transducer and activator of transcription 5A
STX1A syntaxin 1A (brain)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TCTA T-cell leukemia translocation altered
TMEM134 transmembrane protein 134
TNS2 tensin 2
TPM3 tropomyosin 3
TRIM36 tripartite motif containing 36
TSPAN5 tetraspanin 5
USB1 U6 snRNA biogenesis 1
WDR62 WD repeat domain 62
WWC3 WWC family member 3
ZBTB6 zinc finger and BTB domain containing 6
ZNF268 zinc finger protein 268
ZNF329 zinc finger protein 329
ZNF675 zinc finger protein 675