Ventricular Remodeling Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description disease cluster belonging to disease group cardiovascular (Genetic Association Database)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D020257
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Genes

132 genes/proteins associated with the disease Ventricular Remodeling from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
SMAD2 SMAD family member 2 2.88009
SMAD3 SMAD family member 3 2.88009
NOS1 nitric oxide synthase 1 (neuronal) 2.88009
TGFB1 transforming growth factor, beta 1 2.88009
ADRA1A adrenoceptor alpha 1A 2.88009
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 2.17541
NPPA natriuretic peptide A 2.12333
NPPB natriuretic peptide B 1.99351
REN renin 1.9349
IL6 interleukin 6 1.89763
VEGFA vascular endothelial growth factor A 1.86873
EDN1 endothelin 1 1.84144
TNF tumor necrosis factor 1.82919
CCL2 chemokine (C-C motif) ligand 2 1.81337
GJA1 gap junction protein, alpha 1, 43kDa 1.80756
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.76694
BAX BCL2-associated X protein 1.75301
MMP2 matrix metallopeptidase 2 1.72529
TIMP1 TIMP metallopeptidase inhibitor 1 1.71647
ADRB1 adrenoceptor beta 1 1.70657
FASLG Fas ligand (TNF superfamily, member 6) 1.70098
BDKRB2 bradykinin receptor B2 1.6934
IL1B interleukin 1, beta 1.69167
COL3A1 collagen, type III, alpha 1 1.68633
IL10 interleukin 10 1.6774
AGTR1 angiotensin II receptor, type 1 1.67718
ACTA2 actin, alpha 2, smooth muscle, aorta 1.66986
NOS2 nitric oxide synthase 2, inducible 1.66684
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.6662
ACE angiotensin I converting enzyme 1.65358
MMP9 matrix metallopeptidase 9 1.64551
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.63541
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.62983
NOS3 nitric oxide synthase 3 (endothelial cell) 1.6278
BCL2 B-cell CLL/lymphoma 2 1.62268
BCL2L1 BCL2-like 1 1.58467
SOD1 superoxide dismutase 1, soluble 1.58303
VCAM1 vascular cell adhesion molecule 1 1.58279
FN1 fibronectin 1 1.53699
RYR2 ryanodine receptor 2 (cardiac) 1.507
ADRB2 adrenoceptor beta 2, surface 1.50675
HMOX1 heme oxygenase 1 1.48916
CTGF connective tissue growth factor 1.48479
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.45883
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.45511
FAS Fas cell surface death receptor 1.44382
IL1A interleukin 1, alpha 1.44084
ACE2 angiotensin I converting enzyme 2 1.4332
ADRB3 adrenoceptor beta 3 1.41884
PPARA peroxisome proliferator-activated receptor alpha 1.41802
COL4A1 collagen, type IV, alpha 1 1.40953
INS insulin 1.40036
PRKCD protein kinase C, delta 1.39142
MAPK1 mitogen-activated protein kinase 1 1.3827
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.3759
PRKCA protein kinase C, alpha 1.36562
IFNG interferon, gamma 1.35705
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 1.35242
COL1A1 collagen, type I, alpha 1 1.34869
G6PD glucose-6-phosphate dehydrogenase 1.34664
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.34606
TLR4 toll-like receptor 4 1.3443
VIM vimentin 1.33966
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.32577
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.31716
KNG1 kininogen 1 1.31237
CYBB cytochrome b-245, beta polypeptide 1.31237
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.3103
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.29133
MAPK3 mitogen-activated protein kinase 3 1.28641
NCF1 neutrophil cytosolic factor 1 1.28241
GATA4 GATA binding protein 4 1.28119
CAT catalase 1.27286
SMAD7 SMAD family member 7 1.26856
PLAU plasminogen activator, urokinase 1.24496
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.24118
CAV3 caveolin 3 1.24118
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.24056
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.23712
NOX4 NADPH oxidase 4 1.21141
CYCS cytochrome c, somatic 1.20493
APOE apolipoprotein E 1.20196
ALB albumin 1.19704
GNAS GNAS complex locus 1.19445
IFNA1 interferon, alpha 1 1.19345
EGR1 early growth response 1 1.19213
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.19146
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.19047
FOXO3 forkhead box O3 1.18882
EDNRA endothelin receptor type A 1.18026
LPL lipoprotein lipase 1.17366
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 1.17134
ARRB2 arrestin, beta 2 1.16368
MAPK9 mitogen-activated protein kinase 9 1.15933
CYBA cytochrome b-245, alpha polypeptide 1.15831
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.15661
EGFR epidermal growth factor receptor 1.15425
APOB apolipoprotein B 1.15357
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.1485
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 1.14234
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.142
AGTR2 angiotensin II receptor, type 2 1.12906
CREB1 cAMP responsive element binding protein 1 1.12805
CPT1A carnitine palmitoyltransferase 1A (liver) 1.1122
AGER advanced glycosylation end product-specific receptor 1.11046
LEP leptin 1.11046
SPP1 secreted phosphoprotein 1 1.10631
CTSD cathepsin D 1.10246
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.10069
FOS FBJ murine osteosarcoma viral oncogene homolog 1.09998
DES desmin 1.09822
FBXO32 F-box protein 32 1.09822
ICAM1 intercellular adhesion molecule 1 1.09506
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.09226
NFE2L2 nuclear factor, erythroid 2-like 2 1.08372
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.0784
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.07553
NCF2 neutrophil cytosolic factor 2 1.0734
TBK1 TANK-binding kinase 1 1.06515
PPARG peroxisome proliferator-activated receptor gamma 1.05936
CD36 CD36 molecule (thrombospondin receptor) 1.05461
CLU clusterin 1.04465
TP53 tumor protein p53 1.04163
SREBF1 sterol regulatory element binding transcription factor 1 1.03789
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.03604
MPO myeloperoxidase 1.0353
HSPE1 heat shock 10kDa protein 1 1.03308
ADIPOQ adiponectin, C1Q and collagen domain containing 1.03159
FLT1 fms-related tyrosine kinase 1 1.02559
HSPB1 heat shock 27kDa protein 1 1.02003
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.01137
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.01062