Ventilator-associated lung injury_Lung Tissue_GSE2411 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2411
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Genes

600 genes differentially expressed during Ventilator-associated lung injury_Lung Tissue_GSE2411 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) 3.42332
RPS2 ribosomal protein S2 2.89083
NCOR1 nuclear receptor corepressor 1 2.80341
SYNJ2BP synaptojanin 2 binding protein 2.74177
NDRG1 N-myc downstream regulated 1 2.71254
ZNF639 zinc finger protein 639 2.67888
WDR12 WD repeat domain 12 2.67304
TUBGCP5 tubulin, gamma complex associated protein 5 2.48541
SAE1 SUMO1 activating enzyme subunit 1 2.45222
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 2.43564
DPH2 DPH2 homolog (S. cerevisiae) 2.4176
KLHDC4 kelch domain containing 4 2.38267
PCF11 PCF11 cleavage and polyadenylation factor subunit 2.34901
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 2.3414
CKLF chemokine-like factor 2.31755
NFIL3 nuclear factor, interleukin 3 regulated 2.31261
IPO8 importin 8 2.30881
PUS3 pseudouridylate synthase 3 2.30554
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.28649
FAM133B family with sequence similarity 133, member B 2.28304
CYCS cytochrome c, somatic 2.26973
EPB41L4A erythrocyte membrane protein band 4.1 like 4A 2.26569
DEGS1 delta(4)-desaturase, sphingolipid 1 2.26388
TXNL4A thioredoxin-like 4A 2.25845
C5ORF28 chromosome 5 open reading frame 28 2.22608
DACH1 dachshund family transcription factor 1 2.19713
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 2.18646
ECD ecdysoneless homolog (Drosophila) 2.1769
PTH2R parathyroid hormone 2 receptor 2.14625
BYSL bystin-like 2.14386
RPL7A ribosomal protein L7a 2.14343
WWC1 WW and C2 domain containing 1 2.1384
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 2.13793
PBX1 pre-B-cell leukemia homeobox 1 2.13459
ITSN1 intersectin 1 (SH3 domain protein) 2.12664
C1QBP complement component 1, q subcomponent binding protein 2.10161
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) 2.09801
PTGES3 prostaglandin E synthase 3 (cytosolic) 2.08932
PSD3 pleckstrin and Sec7 domain containing 3 2.0868
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 2.08346
RENBP renin binding protein 2.0827
ZWINT ZW10 interacting kinetochore protein 2.08094
UBE2G2 ubiquitin-conjugating enzyme E2G 2 2.07041
GALM galactose mutarotase (aldose 1-epimerase) 2.05828
RAB22A RAB22A, member RAS oncogene family 2.0576
PEX12 peroxisomal biogenesis factor 12 2.0411
LCAT lecithin-cholesterol acyltransferase 2.02377
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 2.01988
KLF15 Kruppel-like factor 15 2.00272
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.98988
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.98354
GALC galactosylceramidase 1.98283
TMEM41B transmembrane protein 41B 1.9759
ZNF644 zinc finger protein 644 1.94772
CPSF3L cleavage and polyadenylation specific factor 3-like 1.93658
TOM1 target of myb1 (chicken) 1.93228
STX7 syntaxin 7 1.92637
RRAGD Ras-related GTP binding D 1.92549
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 1.91897
DAP3 death associated protein 3 1.91405
RABEP1 rabaptin, RAB GTPase binding effector protein 1 1.914
RHEB Ras homolog enriched in brain 1.91045
PRELID1 PRELI domain containing 1 1.90593
SMG8 SMG8 nonsense mediated mRNA decay factor 1.90448
PPP1R42 protein phosphatase 1, regulatory subunit 42 1.90173
FAM122A family with sequence similarity 122A 1.89978
CLIP1 CAP-GLY domain containing linker protein 1 1.86786
HAUS8 HAUS augmin-like complex, subunit 8 1.85528
ZFPM2 zinc finger protein, FOG family member 2 1.85481
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa 1.85407
ANKIB1 ankyrin repeat and IBR domain containing 1 1.85172
ZNF24 zinc finger protein 24 1.84536
GPRC6A G protein-coupled receptor, class C, group 6, member A 1.84079
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 1.8375
KIF2A kinesin heavy chain member 2A 1.83098
CAMSAP1 calmodulin regulated spectrin-associated protein 1 1.83078
KLKB1 kallikrein B, plasma (Fletcher factor) 1 1.82616
ANXA3 annexin A3 1.8183
RBM38 RNA binding motif protein 38 1.81812
CREG1 cellular repressor of E1A-stimulated genes 1 1.81362
BIN1 bridging integrator 1 1.80298
RABGGTB Rab geranylgeranyltransferase, beta subunit 1.80047
ALS2 amyotrophic lateral sclerosis 2 (juvenile) 1.79505
TSC22D3 TSC22 domain family, member 3 1.78472
MYNN myoneurin 1.7839
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 1.78368
JMJD6 jumonji domain containing 6 1.78089
RAN RAN, member RAS oncogene family 1.78068
PLCE1 phospholipase C, epsilon 1 1.78009
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 1.77115
NOA1 nitric oxide associated 1 1.76537
CCDC86 coiled-coil domain containing 86 1.76282
UGP2 UDP-glucose pyrophosphorylase 2 1.75602
SFT2D1 SFT2 domain containing 1 1.75126
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.74884
ENAH enabled homolog (Drosophila) 1.74437
AGFG1 ArfGAP with FG repeats 1 1.74084
SRFBP1 serum response factor binding protein 1 1.73769
PPAN peter pan homolog (Drosophila) 1.73334
CYTIP cytohesin 1 interacting protein 1.72526
TTC7B tetratricopeptide repeat domain 7B 1.72132
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) 1.72012
C3ORF38 chromosome 3 open reading frame 38 1.71554
MED7 mediator complex subunit 7 1.71537
ZNF638 zinc finger protein 638 1.71028
GPATCH4 G patch domain containing 4 1.70612
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 1.70119
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 1.68641
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.67895
CREM cAMP responsive element modulator 1.67804
CACUL1 CDK2-associated, cullin domain 1 1.65461
CENPE centromere protein E, 312kDa 1.65324
PTEN phosphatase and tensin homolog 1.64406
ERBB4 erb-b2 receptor tyrosine kinase 4 1.64265
CCL25 chemokine (C-C motif) ligand 25 1.63578
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 1.62853
C16ORF62 chromosome 16 open reading frame 62 1.62815
MSRA methionine sulfoxide reductase A 1.62738
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 1.62614
SSFA2 sperm specific antigen 2 1.62509
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) 1.62498
TRAM1L1 translocation associated membrane protein 1-like 1 1.62194
TFCP2L1 transcription factor CP2-like 1 1.61294
GADD45G growth arrest and DNA-damage-inducible, gamma 1.6007
RPL6 ribosomal protein L6 1.59741
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 1.59601
PPP4R2 protein phosphatase 4, regulatory subunit 2 1.59195
UBE2J2 ubiquitin-conjugating enzyme E2, J2 1.59163
MSH3 mutS homolog 3 1.58737
PTPN9 protein tyrosine phosphatase, non-receptor type 9 1.5825
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.57482
STX2 syntaxin 2 1.56718
ARL4A ADP-ribosylation factor-like 4A 1.56275
MDFIC MyoD family inhibitor domain containing 1.54975
FNBP1 formin binding protein 1 1.54816
OSBPL6 oxysterol binding protein-like 6 1.54685
C1GALT1C1 C1GALT1-specific chaperone 1 1.54123
USP10 ubiquitin specific peptidase 10 1.5372
SH3RF1 SH3 domain containing ring finger 1 1.5336
DAPK2 death-associated protein kinase 2 1.53168
TBCC tubulin folding cofactor C 1.52882
ATG3 autophagy related 3 1.52382
C7ORF26 chromosome 7 open reading frame 26 1.51882
FAM50A family with sequence similarity 50, member A 1.51809
ZXDC ZXD family zinc finger C 1.51671
EMG1 EMG1 N1-specific pseudouridine methyltransferase 1.51444
RPL12 ribosomal protein L12 1.51404
BTBD1 BTB (POZ) domain containing 1 1.51373
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 1.51153
THOP1 thimet oligopeptidase 1 1.51128
FZD4 frizzled class receptor 4 1.50917
FASTKD5 FAST kinase domains 5 1.49997
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis) 1.49983
WDR55 WD repeat domain 55 1.49134
RTN3 reticulon 3 1.48935
WDFY1 WD repeat and FYVE domain containing 1 1.48926
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 1.48371
TRIB1 tribbles pseudokinase 1 1.48297
TTC1 tetratricopeptide repeat domain 1 1.48025
TERF2 telomeric repeat binding factor 2 1.47718
KLF6 Kruppel-like factor 6 1.47713
C9ORF89 chromosome 9 open reading frame 89 1.47712
DDIT3 DNA-damage-inducible transcript 3 1.47536
YTHDF2 YTH N(6)-methyladenosine RNA binding protein 2 1.47482
RPL27A ribosomal protein L27a 1.47451
FLCN folliculin 1.47315
PLEKHH1 pleckstrin homology domain containing, family H (with MyTH4 domain) member 1 1.47312
GNA13 guanine nucleotide binding protein (G protein), alpha 13 1.47214
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 1.46885
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.46653
ACTG1 actin gamma 1 1.46455
UBE2K ubiquitin-conjugating enzyme E2K 1.46277
DUSP1 dual specificity phosphatase 1 1.45046
SDF2 stromal cell-derived factor 2 1.44774
PNPT1 polyribonucleotide nucleotidyltransferase 1 1.44567
SEC11A SEC11 homolog A (S. cerevisiae) 1.44248
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) 1.44231
AMZ2 archaelysin family metallopeptidase 2 1.43852
SGK1 serum/glucocorticoid regulated kinase 1 1.43679
CHL1 cell adhesion molecule L1-like 1.43302
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.42915
GRPEL2 GrpE-like 2, mitochondrial (E. coli) 1.4263
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 1.42424
RPL17 ribosomal protein L17 1.42377
C2ORF76 chromosome 2 open reading frame 76 1.42349
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 1.42017
CFHR1 complement factor H-related 1 1.41986
H2AFJ H2A histone family, member J 1.41892
ZFAND5 zinc finger, AN1-type domain 5 1.41876
NFYA nuclear transcription factor Y, alpha 1.41824
SPRYD7 SPRY domain containing 7 1.41689
WIPF1 WAS/WASL interacting protein family, member 1 1.41409
SOAT1 sterol O-acyltransferase 1 1.41037
RPL8 ribosomal protein L8 1.40754
TXNDC9 thioredoxin domain containing 9 1.40556
SARS seryl-tRNA synthetase 1.4035
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.40148
CDC73 cell division cycle 73 1.40135
SLC25A30 solute carrier family 25, member 30 1.39908
AEN apoptosis enhancing nuclease 1.39799
MRRF mitochondrial ribosome recycling factor 1.39678
FAS Fas cell surface death receptor 1.39505
IL36G interleukin 36, gamma 1.39302
MCL1 myeloid cell leukemia 1 1.39287
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 1.39094
TMEM131 transmembrane protein 131 1.39062
BMPR1A bone morphogenetic protein receptor, type IA 1.38925
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 1.38628
ERRFI1 ERBB receptor feedback inhibitor 1 1.38207
PRND prion protein 2 (dublet) 1.37989
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.37944
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 1.3793
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 1.37878
MOSPD2 motile sperm domain containing 2 1.37624
RPTN repetin 1.37508
KCMF1 potassium channel modulatory factor 1 1.37475
PKP2 plakophilin 2 1.37369
MED1 mediator complex subunit 1 1.37323
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 1.37211
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1 1.36956
GPN1 GPN-loop GTPase 1 1.36944
RAB6A RAB6A, member RAS oncogene family 1.36933
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.36846
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 1.3675
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 1.36472
RPL10 ribosomal protein L10 1.35649
PHB prohibitin 1.35276
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 1.34768
UPP1 uridine phosphorylase 1 1.34747
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 1.3435
BST1 bone marrow stromal cell antigen 1 1.33805
STAU1 staufen double-stranded RNA binding protein 1 1.33803
NMT2 N-myristoyltransferase 2 1.33796
MKKS McKusick-Kaufman syndrome 1.33211
FAM8A1 family with sequence similarity 8, member A1 1.33095
PAWR PRKC, apoptosis, WT1, regulator 1.32924
CCT4 chaperonin containing TCP1, subunit 4 (delta) 1.32913
FERMT2 fermitin family member 2 1.32885
CSNK2A2 casein kinase 2, alpha prime polypeptide 1.32652
PTCD3 pentatricopeptide repeat domain 3 1.32515
AMPD3 adenosine monophosphate deaminase 3 1.3243
FGD4 FYVE, RhoGEF and PH domain containing 4 1.32428
CHKA choline kinase alpha 1.31936
EIF3L eukaryotic translation initiation factor 3, subunit L 1.31845
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase 1.31258
RFC4 replication factor C (activator 1) 4, 37kDa 1.31163
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 1.31084
TMEM33 transmembrane protein 33 1.30925
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.30877
MITF microphthalmia-associated transcription factor 1.30858
ZNF623 zinc finger protein 623 1.30853
EAPP E2F-associated phosphoprotein 1.30846
LSM10 LSM10, U7 small nuclear RNA associated 1.30802
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 1.30773
SEPHS2 selenophosphate synthetase 2 1.30489
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 1.30428
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.30324
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.29721
TBL1X transducin (beta)-like 1X-linked 1.29649
TRIM33 tripartite motif containing 33 1.29496
TMEM8A transmembrane protein 8A 1.29483
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 1.2933
ZZZ3 zinc finger, ZZ-type containing 3 1.29226
AEBP2 AE binding protein 2 1.29076
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 1.29075
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1.28841
TMEM206 transmembrane protein 206 1.28728
RCC1 regulator of chromosome condensation 1 1.28664
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) 1.28348
MCOLN1 mucolipin 1 1.28226
USP16 ubiquitin specific peptidase 16 1.28171
STRN4 striatin, calmodulin binding protein 4 1.28063
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 1.27961
CCM2 cerebral cavernous malformation 2 1.27906
GADD45B growth arrest and DNA-damage-inducible, beta 1.27236
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 1.27185
AKAP12 A kinase (PRKA) anchor protein 12 1.27043
KLRC1 killer cell lectin-like receptor subfamily C, member 1 1.27015
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.26751
LIN9 lin-9 DREAM MuvB core complex component 1.2673
ARHGAP6 Rho GTPase activating protein 6 1.26537
BRIX1 BRX1, biogenesis of ribosomes 1.26379
SNX1 sorting nexin 1 1.26114
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.2602
JUN jun proto-oncogene 1.25793
SCAF4 SR-related CTD-associated factor 4 1.25487
C1ORF131 chromosome 1 open reading frame 131 1.25476
MORF4L1 mortality factor 4 like 1 1.25453
NIN ninein (GSK3B interacting protein) 1.25315
MAST2 microtubule associated serine/threonine kinase 2 1.25257
LEPR leptin receptor 1.25239
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 1.24987
PACS2 phosphofurin acidic cluster sorting protein 2 1.2492
SNX16 sorting nexin 16 1.24884
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 1.24852
PNPLA7 patatin-like phospholipase domain containing 7 1.24815
TMEM68 transmembrane protein 68 1.24757
EBI3 Epstein-Barr virus induced 3 1.24689
TMEM135 transmembrane protein 135 1.24673
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.24629

decreased expression

Symbol Name Standardized Value
CHPF2 chondroitin polymerizing factor 2 -3.34401
EFNA1 ephrin-A1 -3.32042
ECI2 enoyl-CoA delta isomerase 2 -3.2254
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog -3.01515
TXNIP thioredoxin interacting protein -2.9597
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -2.94684
MCM7 minichromosome maintenance complex component 7 -2.90172
RGS3 regulator of G-protein signaling 3 -2.89758
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.85891
WDR33 WD repeat domain 33 -2.82505
ABHD12 abhydrolase domain containing 12 -2.80719
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -2.7976
RAP1A RAP1A, member of RAS oncogene family -2.76104
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 -2.75931
ABHD16A abhydrolase domain containing 16A -2.74345
GPR85 G protein-coupled receptor 85 -2.68587
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.63533
GMPPA GDP-mannose pyrophosphorylase A -2.63121
ACAA1 acetyl-CoA acyltransferase 1 -2.62784
MAN2B2 mannosidase, alpha, class 2B, member 2 -2.62021
AGTRAP angiotensin II receptor-associated protein -2.58502
FBXL20 F-box and leucine-rich repeat protein 20 -2.54706
THOC3 THO complex 3 -2.54705
TMEM134 transmembrane protein 134 -2.54464
KLHL26 kelch-like family member 26 -2.53156
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.52749
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -2.51727
THTPA thiamine triphosphatase -2.51177
HADH hydroxyacyl-CoA dehydrogenase -2.47474
GLCE glucuronic acid epimerase -2.47261
SYNJ2 synaptojanin 2 -2.47254
TBC1D17 TBC1 domain family, member 17 -2.46065
NCAPH non-SMC condensin I complex, subunit H -2.44353
NRM nurim (nuclear envelope membrane protein) -2.43571
SERTAD3 SERTA domain containing 3 -2.4294
PEX2 peroxisomal biogenesis factor 2 -2.42909
RHOT2 ras homolog family member T2 -2.42771
HELB helicase (DNA) B -2.41612
TRAF5 TNF receptor-associated factor 5 -2.40674
STK10 serine/threonine kinase 10 -2.39827
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 -2.39579
TMEM216 transmembrane protein 216 -2.39033
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -2.37033
BNC1 basonuclin 1 -2.36303
EXTL2 exostosin-like glycosyltransferase 2 -2.36134
PCLO piccolo presynaptic cytomatrix protein -2.35442
B3GNT1 -2.35246
GLI1 GLI family zinc finger 1 -2.34488
SLC41A3 solute carrier family 41, member 3 -2.33835
SIL1 SIL1 nucleotide exchange factor -2.31571
NEU3 sialidase 3 (membrane sialidase) -2.31549
GLI2 GLI family zinc finger 2 -2.31513
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.30274
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.2957
ANLN anillin, actin binding protein -2.29344
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.28997
AMOTL2 angiomotin like 2 -2.28589
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.27458
LPCAT3 lysophosphatidylcholine acyltransferase 3 -2.27079
PHLDB1 pleckstrin homology-like domain, family B, member 1 -2.26012
NAGLU N-acetylglucosaminidase, alpha -2.25334
ELOVL5 ELOVL fatty acid elongase 5 -2.2515
HFE hemochromatosis -2.21584
CUL2 cullin 2 -2.213
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 -2.20963
FBXO3 F-box protein 3 -2.1862
LEPROT leptin receptor overlapping transcript -2.17779
ELMO3 engulfment and cell motility 3 -2.1765
CHN2 chimerin 2 -2.17638
BACE1 beta-site APP-cleaving enzyme 1 -2.17333
FBXW2 F-box and WD repeat domain containing 2 -2.16526
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 -2.16057
NPHP1 nephronophthisis 1 (juvenile) -2.15432
SUGP1 SURP and G patch domain containing 1 -2.14902
TMEM110-MUSTN1 TMEM110-MUSTN1 readthrough -2.14782
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 -2.13255
GLIS2 GLIS family zinc finger 2 -2.12342
ACTC1 actin, alpha, cardiac muscle 1 -2.11657
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -2.1144
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -2.11405
ANXA6 annexin A6 -2.10788
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.10768
SH3BP5L SH3-binding domain protein 5-like -2.08812
CACFD1 calcium channel flower domain containing 1 -2.08259
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -2.07975
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.07928
PCDH18 protocadherin 18 -2.07736
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -2.07693
SIAE sialic acid acetylesterase -2.06601
CD79B CD79b molecule, immunoglobulin-associated beta -2.06564
STX5 syntaxin 5 -2.05374
LPL lipoprotein lipase -2.04842
ACP2 acid phosphatase 2, lysosomal -2.04375
TMEM53 transmembrane protein 53 -2.04124
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -2.03571
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.03527
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 -2.02672
ACTA2 actin, alpha 2, smooth muscle, aorta -2.02344
RREB1 ras responsive element binding protein 1 -2.02332
DKK1 dickkopf WNT signaling pathway inhibitor 1 -2.02263
UROD uroporphyrinogen decarboxylase -2.01289
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain -2.00786
TAGLN2 transgelin 2 -2.00159
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 -2.00104
RDM1 RAD52 motif containing 1 -1.99867
ZBTB46 zinc finger and BTB domain containing 46 -1.99505
ATP13A2 ATPase type 13A2 -1.9937
LOC102723475 putative uncharacterized protein LOC388820 -1.98155
CD19 CD19 molecule -1.97513
TMED1 transmembrane emp24 protein transport domain containing 1 -1.97436
GPR34 G protein-coupled receptor 34 -1.97375
ALDOC aldolase C, fructose-bisphosphate -1.97306
TMEM203 transmembrane protein 203 -1.97153
DLL4 delta-like 4 (Drosophila) -1.96867
MGST2 microsomal glutathione S-transferase 2 -1.96419
PDHB pyruvate dehydrogenase (lipoamide) beta -1.96286
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -1.95981
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -1.95934
OSBPL2 oxysterol binding protein-like 2 -1.94843
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -1.93985
PLD3 phospholipase D family, member 3 -1.9384
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -1.93635
KATNB1 katanin p80 (WD repeat containing) subunit B 1 -1.93226
SOX4 SRY (sex determining region Y)-box 4 -1.93186
PTER phosphotriesterase related -1.93167
MAB21L1 mab-21-like 1 (C. elegans) -1.93157
NXN nucleoredoxin -1.92705
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -1.92547
PFKM phosphofructokinase, muscle -1.92354
FMO1 flavin containing monooxygenase 1 -1.91691
CREB3 cAMP responsive element binding protein 3 -1.91619
TERF2IP telomeric repeat binding factor 2, interacting protein -1.91534
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -1.91514
LZTFL1 leucine zipper transcription factor-like 1 -1.91297
SIN3B SIN3 transcription regulator family member B -1.91278
S1PR4 sphingosine-1-phosphate receptor 4 -1.91226
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 -1.91049
TM7SF3 transmembrane 7 superfamily member 3 -1.90682
TEAD4 TEA domain family member 4 -1.89764
RAB3D RAB3D, member RAS oncogene family -1.89517
CD27 CD27 molecule -1.89421
CCBL2 cysteine conjugate-beta lyase 2 -1.89267
BACE2 beta-site APP-cleaving enzyme 2 -1.89151
RFC2 replication factor C (activator 1) 2, 40kDa -1.88545
DAP death-associated protein -1.88207
CLEC14A C-type lectin domain family 14, member A -1.86853
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 -1.8637
PNPO pyridoxamine 5'-phosphate oxidase -1.86024
PPT2 palmitoyl-protein thioesterase 2 -1.85853
NCALD neurocalcin delta -1.85453
TRIM26 tripartite motif containing 26 -1.85426
NFE2L3 nuclear factor, erythroid 2-like 3 -1.84872
TRPC3 transient receptor potential cation channel, subfamily C, member 3 -1.84574
ZNF394 zinc finger protein 394 -1.84567
AK1 adenylate kinase 1 -1.84446
WIPI1 WD repeat domain, phosphoinositide interacting 1 -1.84205
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -1.83665
GSTM4 glutathione S-transferase mu 4 -1.83535
RANBP3 RAN binding protein 3 -1.82657
TNK2 tyrosine kinase, non-receptor, 2 -1.82585
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 -1.8122
RECQL RecQ helicase-like -1.80496
SOWAHA sosondowah ankyrin repeat domain family member A -1.80116
RGS4 regulator of G-protein signaling 4 -1.79773
SPNS1 spinster homolog 1 (Drosophila) -1.79015
CBX4 chromobox homolog 4 -1.78932
GAB1 GRB2-associated binding protein 1 -1.78895
C21ORF2 chromosome 21 open reading frame 2 -1.77952
SAMD10 sterile alpha motif domain containing 10 -1.77769
GRM8 glutamate receptor, metabotropic 8 -1.77432
DUSP22 dual specificity phosphatase 22 -1.76557
SEPT6 septin 6 -1.76376
KLF10 Kruppel-like factor 10 -1.76269
TMEM209 transmembrane protein 209 -1.75474
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -1.7547
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -1.75408
CNOT6 CCR4-NOT transcription complex, subunit 6 -1.74275
SPON1 spondin 1, extracellular matrix protein -1.73914
MRGPRF MAS-related GPR, member F -1.73881
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -1.73853
XYLT2 xylosyltransferase II -1.73742
GRB7 growth factor receptor-bound protein 7 -1.73126
RUSC1 RUN and SH3 domain containing 1 -1.7306
S100A3 S100 calcium binding protein A3 -1.73023
RBM3 RNA binding motif (RNP1, RRM) protein 3 -1.73008
CBX2 chromobox homolog 2 -1.72686
PCCB propionyl CoA carboxylase, beta polypeptide -1.72647
SCARA3 scavenger receptor class A, member 3 -1.72516
IL7 interleukin 7 -1.72156
CRIP1 cysteine-rich protein 1 (intestinal) -1.71926
NRARP NOTCH-regulated ankyrin repeat protein -1.71848
PPP1R3C protein phosphatase 1, regulatory subunit 3C -1.71827
SLC12A9 solute carrier family 12, member 9 -1.71368
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa -1.71357
MEF2C myocyte enhancer factor 2C -1.71307
XAB2 XPA binding protein 2 -1.71138
CD164 CD164 molecule, sialomucin -1.71066
ENG endoglin -1.70429
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 -1.70251
ZDHHC12 zinc finger, DHHC-type containing 12 -1.70165
CEP70 centrosomal protein 70kDa -1.70059
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase -1.69931
CLCN3 chloride channel, voltage-sensitive 3 -1.69694
ACAA2 acetyl-CoA acyltransferase 2 -1.69281
CIAPIN1 cytokine induced apoptosis inhibitor 1 -1.69201
APCDD1 adenomatosis polyposis coli down-regulated 1 -1.68887
FLT4 fms-related tyrosine kinase 4 -1.6882
RNF17 ring finger protein 17 -1.68561
TMEM161A transmembrane protein 161A -1.68358
FKBP10 FK506 binding protein 10, 65 kDa -1.68302
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -1.68227
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -1.67869
FECH ferrochelatase -1.67782
NMRK1 nicotinamide riboside kinase 1 -1.67495
NUB1 negative regulator of ubiquitin-like proteins 1 -1.66715
FCRLA Fc receptor-like A -1.6671
IFT140 intraflagellar transport 140 -1.66527
RASA4 RAS p21 protein activator 4 -1.66315
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 -1.66257
DVL2 dishevelled segment polarity protein 2 -1.66103
ATG2A autophagy related 2A -1.65902
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -1.65808
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit -1.65636
RXFP2 relaxin/insulin-like family peptide receptor 2 -1.65367
PLD1 phospholipase D1, phosphatidylcholine-specific -1.65349
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 -1.65227
KLHDC3 kelch domain containing 3 -1.65147
MPZL2 myelin protein zero-like 2 -1.65084
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -1.64331
VWA8 von Willebrand factor A domain containing 8 -1.64322
ACAD9 acyl-CoA dehydrogenase family, member 9 -1.63585
USP43 ubiquitin specific peptidase 43 -1.63049
PSMC3IP PSMC3 interacting protein -1.62969
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 -1.62694
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -1.62568
JARID2 jumonji, AT rich interactive domain 2 -1.62259
TMED4 transmembrane emp24 protein transport domain containing 4 -1.62041
ACY3 aminoacylase 3 -1.61977
CDCA7L cell division cycle associated 7-like -1.61573
HES6 hes family bHLH transcription factor 6 -1.61457
COL6A2 collagen, type VI, alpha 2 -1.61352
WNT5A wingless-type MMTV integration site family, member 5A -1.60906
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -1.60449
EFCAB2 EF-hand calcium binding domain 2 -1.60076
MEF2D myocyte enhancer factor 2D -1.59987
ATP9A ATPase, class II, type 9A -1.5973
RIMKLB ribosomal modification protein rimK-like family member B -1.59623
CA2 carbonic anhydrase II -1.59586
ATG4D autophagy related 4D, cysteine peptidase -1.5957
CUL9 cullin 9 -1.59542
MSC musculin -1.59445
CASP2 caspase 2, apoptosis-related cysteine peptidase -1.59254
CCDC88C coiled-coil domain containing 88C -1.59219
FCRL1 Fc receptor-like 1 -1.58911
LOH12CR1 loss of heterozygosity, 12, chromosomal region 1 -1.58687
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 -1.58664
SGSH N-sulfoglucosamine sulfohydrolase -1.58293
EPB41L1 erythrocyte membrane protein band 4.1-like 1 -1.58207
FJX1 four jointed box 1 (Drosophila) -1.58138
INPP5K inositol polyphosphate-5-phosphatase K -1.5726
KIAA1324 KIAA1324 -1.57235
PLIN5 perilipin 5 -1.57214
PRKCQ protein kinase C, theta -1.57075
RFX1 regulatory factor X, 1 (influences HLA class II expression) -1.56987
CDK7 cyclin-dependent kinase 7 -1.56806
MED14 mediator complex subunit 14 -1.56266
SH3BP1 SH3-domain binding protein 1 -1.55485
FAM173A family with sequence similarity 173, member A -1.5547
MEN1 multiple endocrine neoplasia I -1.55427
RAD18 RAD18 E3 ubiquitin protein ligase -1.55319
RNF32 ring finger protein 32 -1.55259
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -1.5523
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -1.55052
RXRA retinoid X receptor, alpha -1.54937
ACVR2A activin A receptor, type IIA -1.54871
C19ORF25 chromosome 19 open reading frame 25 -1.54606
C5ORF15 chromosome 5 open reading frame 15 -1.54488
ACP1 acid phosphatase 1, soluble -1.54095
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 -1.5358
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase -1.5357
NCR1 natural cytotoxicity triggering receptor 1 -1.53429
HLA-DOA major histocompatibility complex, class II, DO alpha -1.53269
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 -1.53175
C1QTNF3 C1q and tumor necrosis factor related protein 3 -1.53078
PHKG2 phosphorylase kinase, gamma 2 (testis) -1.53012
TSHZ2 teashirt zinc finger homeobox 2 -1.52955
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 -1.5293
RPRD1B regulation of nuclear pre-mRNA domain containing 1B -1.52466
COL6A1 collagen, type VI, alpha 1 -1.52383
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -1.51967
CDK2 cyclin-dependent kinase 2 -1.51717
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) -1.51516
MPHOSPH6 M-phase phosphoprotein 6 -1.51516
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 -1.51452
CBR4 carbonyl reductase 4 -1.50771
ESYT1 extended synaptotagmin-like protein 1 -1.50279
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 -1.50253
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha -1.49742
SLCO2A1 solute carrier organic anion transporter family, member 2A1 -1.4971
MPG N-methylpurine-DNA glycosylase -1.4944