Vasospasm, Intracranial Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D020301
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Genes

323 genes/proteins associated with the disease Vasospasm, Intracranial from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
S100B S100 calcium binding protein B 2.88009
S100A4 S100 calcium binding protein A4 2.88009
S100A6 S100 calcium binding protein A6 2.88009
PLAT plasminogen activator, tissue 2.88009
S100A1 S100 calcium binding protein A1 2.88009
MAPK3 mitogen-activated protein kinase 3 2.12622
MAPK1 mitogen-activated protein kinase 1 2.11922
TNF tumor necrosis factor 2.02361
BAX BCL2-associated X protein 2.00329
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.95964
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.9545
PRL prolactin 1.945
BCL2 B-cell CLL/lymphoma 2 1.90109
SOD1 superoxide dismutase 1, soluble 1.89894
FOS FBJ murine osteosarcoma viral oncogene homolog 1.89327
JUN jun proto-oncogene 1.8836
IL1B interleukin 1, beta 1.88159
NOS1 nitric oxide synthase 1 (neuronal) 1.87426
CALCA calcitonin-related polypeptide alpha 1.85887
BDNF brain-derived neurotrophic factor 1.84569
TGFB1 transforming growth factor, beta 1 1.84323
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.84323
CREB1 cAMP responsive element binding protein 1 1.8409
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.83717
CAT catalase 1.82954
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.79981
IL6 interleukin 6 1.78473
PRKCB protein kinase C, beta 1.78246
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.76694
BCL2L1 BCL2-like 1 1.75321
POMC proopiomelanocortin 1.75261
EDN1 endothelin 1 1.74661
VEGFA vascular endothelial growth factor A 1.74019
IGF1 insulin-like growth factor 1 (somatomedin C) 1.73958
TIMP1 TIMP metallopeptidase inhibitor 1 1.73251
SOD2 superoxide dismutase 2, mitochondrial 1.73028
DUSP1 dual specificity phosphatase 1 1.72696
TH tyrosine hydroxylase 1.71891
TAC1 tachykinin, precursor 1 1.71769
CXCL10 chemokine (C-X-C motif) ligand 10 1.71193
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.69146
TP53 tumor protein p53 1.69146
EGR1 early growth response 1 1.67398
MAP2K1 mitogen-activated protein kinase kinase 1 1.66878
INS insulin 1.66706
GSK3B glycogen synthase kinase 3 beta 1.65023
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.64978
FGF2 fibroblast growth factor 2 (basic) 1.64685
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.62199
MAPK8 mitogen-activated protein kinase 8 1.6146
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.60641
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.60524
PRKCD protein kinase C, delta 1.60221
NOS2 nitric oxide synthase 2, inducible 1.59849
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.59849
CCL2 chemokine (C-C motif) ligand 2 1.5903
FN1 fibronectin 1 1.58654
RGS4 regulator of G-protein signaling 4 1.58184
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.57829
PRKCE protein kinase C, epsilon 1.57378
PENK proenkephalin 1.57186
CCND1 cyclin D1 1.57018
NGF nerve growth factor (beta polypeptide) 1.56558
PARP1 poly (ADP-ribose) polymerase 1 1.56019
JUNB jun B proto-oncogene 1.55747
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.55108
NPPA natriuretic peptide A 1.54427
EDNRB endothelin receptor type B 1.53941
IFNG interferon, gamma 1.53481
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.53407
ADRA1B adrenoceptor alpha 1B 1.53159
HMOX1 heme oxygenase 1 1.53012
CXCL8 chemokine (C-X-C motif) ligand 8 1.4989
COL1A2 collagen, type I, alpha 2 1.49584
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 1.49558
APP amyloid beta (A4) precursor protein 1.492
DRD2 dopamine receptor D2 1.48967
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.48659
F2 coagulation factor II (thrombin) 1.48402
MAPK14 mitogen-activated protein kinase 14 1.48093
IL10 interleukin 10 1.4794
NR4A1 nuclear receptor subfamily 4, group A, member 1 1.47813
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.47426
S100A9 S100 calcium binding protein A9 1.47219
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.4567
MAOB monoamine oxidase B 1.45273
MMP1 matrix metallopeptidase 1 1.44899
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.44899
NPPC natriuretic peptide C 1.4479
THBS1 thrombospondin 1 1.44708
ADRB1 adrenoceptor beta 1 1.44517
NOS3 nitric oxide synthase 3 (endothelial cell) 1.43892
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.43537
CRH corticotropin releasing hormone 1.43239
ADRA2A adrenoceptor alpha 2A 1.43021
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.42859
NPY neuropeptide Y 1.41992
TGFB2 transforming growth factor, beta 2 1.41829
SELE selectin E 1.41146
F3 coagulation factor III (thromboplastin, tissue factor) 1.40486
LIF leukemia inhibitory factor 1.38584
ADORA2A adenosine A2a receptor 1.38584
ADRA1D adrenoceptor alpha 1D 1.38555
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.38242
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.38071
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.37018
GFAP glial fibrillary acidic protein 1.36706
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.36332
REN renin 1.36133
GNAS GNAS complex locus 1.35734
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.35531
ADRB2 adrenoceptor beta 2, surface 1.35415
HOMER1 homer scaffolding protein 1 1.35069
COMT catechol-O-methyltransferase 1.34983
CDK1 cyclin-dependent kinase 1 1.34897
AVP arginine vasopressin 1.34897
DDIT3 DNA-damage-inducible transcript 3 1.3484
PRKCA protein kinase C, alpha 1.34285
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.33672
EGFR epidermal growth factor receptor 1.33346
LEP leptin 1.33257
IL4 interleukin 4 1.33199
PKM pyruvate kinase, muscle 1.3231
GDF15 growth differentiation factor 15 1.32251
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.32132
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.32074
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.31985
ADM adrenomedullin 1.31566
CLU clusterin 1.31327
FASLG Fas ligand (TNF superfamily, member 6) 1.31059
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.30482
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.30177
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.29812
CCND3 cyclin D3 1.2975
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.2944
VCAM1 vascular cell adhesion molecule 1 1.29225
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.28889
BAK1 BCL2-antagonist/killer 1 1.28703
ADCY5 adenylate cyclase 5 1.2861
LPL lipoprotein lipase 1.28579
MAOA monoamine oxidase A 1.28518
GDNF glial cell derived neurotrophic factor 1.28364
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.28364
GSTM1 glutathione S-transferase mu 1 1.28058
NCF1 neutrophil cytosolic factor 1 1.28027
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.27347
BID BH3 interacting domain death agonist 1.27162
GCLC glutamate-cysteine ligase, catalytic subunit 1.27101
MAPK9 mitogen-activated protein kinase 9 1.26917
GAP43 growth associated protein 43 1.26856
EGF epidermal growth factor 1.26825
CCL3 chemokine (C-C motif) ligand 3 1.267
CXCL9 chemokine (C-X-C motif) ligand 9 1.26576
ICAM1 intercellular adhesion molecule 1 1.26421
FAS Fas cell surface death receptor 1.26329
IL1A interleukin 1, alpha 1.2599
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.25619
INHA inhibin, alpha 1.25619
ACE angiotensin I converting enzyme 1.25463
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.24997
CKB creatine kinase, brain 1.24718
CREM cAMP responsive element modulator 1.24496
PDE1B phosphodiesterase 1B, calmodulin-dependent 1.24433
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.24401
DRD3 dopamine receptor D3 1.24056
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.2368
PPARA peroxisome proliferator-activated receptor alpha 1.23392
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.23137
CCL5 chemokine (C-C motif) ligand 5 1.22821
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.22501
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.22306
PPARG peroxisome proliferator-activated receptor gamma 1.22274
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.2208
OXT oxytocin/neurophysin I prepropeptide 1.2208
MMP2 matrix metallopeptidase 2 1.21984
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.21599
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.21534
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.21043
MKI67 marker of proliferation Ki-67 1.20427
IGFBP5 insulin-like growth factor binding protein 5 1.20427
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.20427
MAP1A microtubule-associated protein 1A 1.20163
CREBBP CREB binding protein 1.20031
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.19868
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.19345
G6PD glucose-6-phosphate dehydrogenase 1.19213
BAD BCL2-associated agonist of cell death 1.19213
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 1.18685
SPTAN1 spectrin, alpha, non-erythrocytic 1 1.18587
VIM vimentin 1.18456
S100A8 S100 calcium binding protein A8 1.18293
TFRC transferrin receptor 1.17959
EGR3 early growth response 3 1.17662
COL1A1 collagen, type I, alpha 1 1.17497
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.17399
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.17235
TGFA transforming growth factor, alpha 1.17202
STAR steroidogenic acute regulatory protein 1.16733
GH1 growth hormone 1 1.165
PER1 period circadian clock 1 1.165
GSTP1 glutathione S-transferase pi 1 1.16137
PTPN12 protein tyrosine phosphatase, non-receptor type 12 1.16137
CYCS cytochrome c, somatic 1.1607
CDK4 cyclin-dependent kinase 4 1.16001
COL18A1 collagen, type XVIII, alpha 1 1.15933
ANXA1 annexin A1 1.15797
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.15763
HSPA1A heat shock 70kDa protein 1A 1.15763
ESR1 estrogen receptor 1 1.1556
COL3A1 collagen, type III, alpha 1 1.1529
LHB luteinizing hormone beta polypeptide 1.15189
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.15122
ELK1 ELK1, member of ETS oncogene family 1.15122
OPRM1 opioid receptor, mu 1 1.14954
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.1485
DRD1 dopamine receptor D1 1.14781
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.1461
ACTA2 actin, alpha 2, smooth muscle, aorta 1.1461
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 1.1461
NTS neurotensin 1.14575
PRKCZ protein kinase C, zeta 1.14575
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.14507
SOCS3 suppressor of cytokine signaling 3 1.14438
BDKRB2 bradykinin receptor B2 1.1403
NTF3 neurotrophin 3 1.1403
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.13929
ADRB3 adrenoceptor beta 3 1.13793
ADRA1A adrenoceptor alpha 1A 1.13552
FOSL2 FOS-like antigen 2 1.13245
GCLM glutamate-cysteine ligase, modifier subunit 1.13143
CTSB cathepsin B 1.12973
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.12906
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.12805
GATA3 GATA binding protein 3 1.12771
CDK2 cyclin-dependent kinase 2 1.12703
SYN2 synapsin II 1.12668
MMP9 matrix metallopeptidase 9 1.12426
CAV1 caveolin 1, caveolae protein, 22kDa 1.12185
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.12048
NCF2 neutrophil cytosolic factor 2 1.12014
TIMP2 TIMP metallopeptidase inhibitor 2 1.11606
MMP3 matrix metallopeptidase 3 1.11431
ENO2 enolase 2 (gamma, neuronal) 1.1129
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.1129
FOSL1 FOS-like antigen 1 1.11151
ACO2 aconitase 2, mitochondrial 1.11081
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 1.10459
HSF1 heat shock transcription factor 1 1.1014
ACHE acetylcholinesterase (Yt blood group) 1.09471
GCG glucagon 1.09262
ERBB4 erb-b2 receptor tyrosine kinase 4 1.09226
KLF4 Kruppel-like factor 4 (gut) 1.09226
GSK3A glycogen synthase kinase 3 alpha 1.09226
SEPP1 selenoprotein P, plasma, 1 1.09011
CALM2 calmodulin 2 (phosphorylase kinase, delta) 1.08833
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.08833
GSR glutathione reductase 1.08797
FGF10 fibroblast growth factor 10 1.08407
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.08372
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 1.08337
CXCL2 chemokine (C-X-C motif) ligand 2 1.08301
SPP1 secreted phosphoprotein 1 1.08091
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.07732
DIO2 deiodinase, iodothyronine, type II 1.07732
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.07589
BIRC5 baculoviral IAP repeat containing 5 1.07447
TYR tyrosinase 1.07305
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 1.06987
ADORA3 adenosine A3 receptor 1.06952
NRG1 neuregulin 1 1.06917
FSHB follicle stimulating hormone, beta polypeptide 1.06917
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.06698
FLT1 fms-related tyrosine kinase 1 1.06661
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.06479
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.06479
HSPA8 heat shock 70kDa protein 8 1.06406
GRM1 glutamate receptor, metabotropic 1 1.06225
RYR2 ryanodine receptor 2 (cardiac) 1.06188
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.0608
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.06008
TRGV9 T cell receptor gamma variable 9 1.06008
TUBA4A tubulin, alpha 4a 1.05864
CD36 CD36 molecule (thrombospondin receptor) 1.05864
IL18 interleukin 18 1.0561
NQO2 NAD(P)H dehydrogenase, quinone 2 1.05498
MAP1B microtubule-associated protein 1B 1.05498
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.05386
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.052
CCKBR cholecystokinin B receptor 1.05126
CCNB1 cyclin B1 1.05015
GJA1 gap junction protein, alpha 1, 43kDa 1.04978
STAT1 signal transducer and activator of transcription 1, 91kDa 1.04978
EDNRA endothelin receptor type A 1.04904
LMCD1 LIM and cysteine-rich domains 1 1.04794
XDH xanthine dehydrogenase 1.04721
JUND jun D proto-oncogene 1.04721
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.04314
RB1 retinoblastoma 1 1.04201
UBE2I ubiquitin-conjugating enzyme E2I 1.04126
MCL1 myeloid cell leukemia 1 1.04088
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.03976
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 1.03567
RGS2 regulator of G-protein signaling 2 1.03567
SFTPB surfactant protein B 1.0353
GLUL glutamate-ammonia ligase 1.03382
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.03382
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 1.03159
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 1.03009
PCNA proliferating cell nuclear antigen 1.02821
PTK2 protein tyrosine kinase 2 1.02634
BBC3 BCL2 binding component 3 1.02634
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.02522
CYBA cytochrome b-245, alpha polypeptide 1.02447
CYBB cytochrome b-245, beta polypeptide 1.02299
NR5A2 nuclear receptor subfamily 5, group A, member 2 1.02262
PPP1R12A protein phosphatase 1, regulatory subunit 12A 1.02262
HSPB1 heat shock 27kDa protein 1 1.01928
CCNG1 cyclin G1 1.01776
NPPB natriuretic peptide B 1.01776
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.01399
IER3 immediate early response 3 1.01249
IL2 interleukin 2 1.01137
ALPK2 alpha-kinase 2 1.01099