Vasculitis, Leukocytoclastic, Cutaneous Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D018366
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Genes

693 genes/proteins associated with the disease Vasculitis, Leukocytoclastic, Cutaneous from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
TNF tumor necrosis factor 2.45169
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.44718
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.43819
IL6 interleukin 6 2.41001
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.37277
CAT catalase 2.31684
CXCL8 chemokine (C-X-C motif) ligand 8 2.30861
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 2.29299
BAX BCL2-associated X protein 2.26137
IL1B interleukin 1, beta 2.25939
BCL2 B-cell CLL/lymphoma 2 2.24993
IFNG interferon, gamma 2.22677
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 2.20761
NOS2 nitric oxide synthase 2, inducible 2.17336
CCL2 chemokine (C-C motif) ligand 2 2.16958
IL10 interleukin 10 2.16214
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.15035
SOD2 superoxide dismutase 2, mitochondrial 2.11353
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.10319
REN renin 2.09672
MAPK3 mitogen-activated protein kinase 3 2.08464
VEGFA vascular endothelial growth factor A 2.08332
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.0808
HMOX1 heme oxygenase 1 2.07866
MAPK1 mitogen-activated protein kinase 1 2.07552
FOS FBJ murine osteosarcoma viral oncogene homolog 2.06331
MMP2 matrix metallopeptidase 2 2.04618
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.04228
TP53 tumor protein p53 2.03965
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 2.03265
JUN jun proto-oncogene 1.9948
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.99279
FAS Fas cell surface death receptor 1.98945
TGFB1 transforming growth factor, beta 1 1.97954
EDN1 endothelin 1 1.97655
MPO myeloperoxidase 1.97067
F3 coagulation factor III (thromboplastin, tissue factor) 1.96847
DDIT3 DNA-damage-inducible transcript 3 1.96147
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.94674
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.94233
FASLG Fas ligand (TNF superfamily, member 6) 1.93277
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 1.93056
IL2 interleukin 2 1.92737
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.92453
MMP9 matrix metallopeptidase 9 1.89536
BCL2L1 BCL2-like 1 1.89106
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.88409
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.88327
PPARG peroxisome proliferator-activated receptor gamma 1.88142
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.87476
ICAM1 intercellular adhesion molecule 1 1.87126
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.85852
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.85782
IGF1 insulin-like growth factor 1 (somatomedin C) 1.85362
MBP myelin basic protein 1.85116
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.84517
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.84464
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.84198
ALB albumin 1.83574
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.83361
EGFR epidermal growth factor receptor 1.82884
GSK3B glycogen synthase kinase 3 beta 1.82884
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.80737
ADRB1 adrenoceptor beta 1 1.79732
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.78682
FASN fatty acid synthase 1.76966
NPY neuropeptide Y 1.7683
NOS3 nitric oxide synthase 3 (endothelial cell) 1.76443
IL4 interleukin 4 1.76269
GSTP1 glutathione S-transferase pi 1 1.75954
APP amyloid beta (A4) precursor protein 1.75895
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.75856
EGR1 early growth response 1 1.74782
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.74681
IL5 interleukin 5 1.73455
MAPK14 mitogen-activated protein kinase 14 1.7255
NPPA natriuretic peptide A 1.72364
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.71687
CCND1 cyclin D1 1.71235
VCAM1 vascular cell adhesion molecule 1 1.70906
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.70678
INS insulin 1.70657
RB1 retinoblastoma 1 1.70368
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.69846
ADRB2 adrenoceptor beta 2, surface 1.69103
MAPK8 mitogen-activated protein kinase 8 1.67505
IL1A interleukin 1, alpha 1.67051
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.66813
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.66813
CCND2 cyclin D2 1.66425
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.65996
IL12B interleukin 12B 1.65068
PPARA peroxisome proliferator-activated receptor alpha 1.63877
BDNF brain-derived neurotrophic factor 1.63496
SOD1 superoxide dismutase 1, soluble 1.6325
ADIPOQ adiponectin, C1Q and collagen domain containing 1.62445
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.6229
CYCS cytochrome c, somatic 1.61897
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.61759
DNASE1 deoxyribonuclease I 1.60641
IRS1 insulin receptor substrate 1 1.60617
LEP leptin 1.6036
TIMP1 TIMP metallopeptidase inhibitor 1 1.59638
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.5903
MAPK9 mitogen-activated protein kinase 9 1.58959
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.58724
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.57522
PARP1 poly (ADP-ribose) polymerase 1 1.56607
S100A9 S100 calcium binding protein A9 1.55946
COL1A1 collagen, type I, alpha 1 1.55673
C10ORF10 chromosome 10 open reading frame 10 1.55451
GATA3 GATA binding protein 3 1.55231
TIMP2 TIMP metallopeptidase inhibitor 2 1.54961
INHBE inhibin, beta E 1.54937
CREB1 cAMP responsive element binding protein 1 1.54523
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.5433
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.54257
POMC proopiomelanocortin 1.53892
ODC1 ornithine decarboxylase 1 1.53579
DUSP1 dual specificity phosphatase 1 1.53431
PCNA proliferating cell nuclear antigen 1.53159
S1PR1 sphingosine-1-phosphate receptor 1 1.52591
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.52262
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.52237
LPL lipoprotein lipase 1.52237
SCD stearoyl-CoA desaturase (delta-9-desaturase) 1.52011
CXCL10 chemokine (C-X-C motif) ligand 10 1.51506
FADS2 fatty acid desaturase 2 1.51405
ASNS asparagine synthetase (glutamine-hydrolyzing) 1.51355
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.51155
CFLAR CASP8 and FADD-like apoptosis regulator 1.5113
CRH corticotropin releasing hormone 1.5113
ACTA2 actin, alpha 2, smooth muscle, aorta 1.50776
EGF epidermal growth factor 1.50069
GSTT1 glutathione S-transferase theta 1 1.49609
GADD45A growth arrest and DNA-damage-inducible, alpha 1.49482
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic 1.49226
CRP C-reactive protein, pentraxin-related 1.49122
NUPR1 nuclear protein, transcriptional regulator, 1 1.48196
PRLR prolactin receptor 1.47889
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.47889
IL12A interleukin 12A 1.474
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.474
CLU clusterin 1.46356
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 1.46225
ARC activity-regulated cytoskeleton-associated protein 1.46146
GSTM1 glutathione S-transferase mu 1 1.45643
MCL1 myeloid cell leukemia 1 1.4559
C1S complement component 1, s subcomponent 1.45511
GPX1 glutathione peroxidase 1 1.45511
IGF1R insulin-like growth factor 1 receptor 1.45458
MMP3 matrix metallopeptidase 3 1.45063
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 1.44653
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.4449
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.437
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.4332
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 1.43293
PRKCB protein kinase C, beta 1.43239
WIPI1 WD repeat domain, phosphoinositide interacting 1 1.4313
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 1.42777
SPP1 secreted phosphoprotein 1 1.42589
MYH7 myosin, heavy chain 7, cardiac muscle, beta 1.42074
BIRC5 baculoviral IAP repeat containing 5 1.41748
IGFBP3 insulin-like growth factor binding protein 3 1.41586
NPPB natriuretic peptide B 1.41451
KDR kinase insert domain receptor 1.41396
BID BH3 interacting domain death agonist 1.41257
MAP2K2 mitogen-activated protein kinase kinase 2 1.41229
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.40787
RELN reelin 1.40705
LDLR low density lipoprotein receptor 1.40705
CCL3 chemokine (C-C motif) ligand 3 1.40677
CYR61 cysteine-rich, angiogenic inducer, 61 1.40568
PRL prolactin 1.40401
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.40401
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.40148
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.3998
COL3A1 collagen, type III, alpha 1 1.39479
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.3917
TGFB2 transforming growth factor, beta 2 1.39058
HSPA1B heat shock 70kDa protein 1B 1.39058
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 1.37874
PON1 paraoxonase 1 1.37676
IL18 interleukin 18 1.37676
MMP13 matrix metallopeptidase 13 1.37619
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.37332
APOE apolipoprotein E 1.37189
GJA1 gap junction protein, alpha 1, 43kDa 1.36876
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.3682
CTSB cathepsin B 1.36619
LCN2 lipocalin 2 1.36619
VIM vimentin 1.36562
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.36418
GNAS GNAS complex locus 1.36304
SELL selectin L 1.36275
COL18A1 collagen, type XVIII, alpha 1 1.36275
GSR glutathione reductase 1.36247
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.36019
ATM ATM serine/threonine kinase 1.35821
SREBF1 sterol regulatory element binding transcription factor 1 1.35618
DHFR dihydrofolate reductase 1.35299
SERINC3 serine incorporator 3 1.35213
TJP1 tight junction protein 1 1.34811
NR0B2 nuclear receptor subfamily 0, group B, member 2 1.34811
PRKCZ protein kinase C, zeta 1.34576
S100A10 S100 calcium binding protein A10 1.34576
CYP3A cytochrome P450, family 3, subfamily A 1.34256
ADRB3 adrenoceptor beta 3 1.33612
EIF4E eukaryotic translation initiation factor 4E 1.33583
CXCL2 chemokine (C-X-C motif) ligand 2 1.33553
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.33405
PHYH phytanoyl-CoA 2-hydroxylase 1.33316
HSPA1A heat shock 70kDa protein 1A 1.33199
HSPB1 heat shock 27kDa protein 1 1.33052
GPNMB glycoprotein (transmembrane) nmb 1.32964
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.32876
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.32876
NQO1 NAD(P)H dehydrogenase, quinone 1 1.32756
PRKCE protein kinase C, epsilon 1.32428
TIMP3 TIMP metallopeptidase inhibitor 3 1.32192
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha 1.31985
RPS19 ribosomal protein S19 1.31985
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.31716
EPO erythropoietin 1.31716
THBS1 thrombospondin 1 1.31506
CDC42 cell division cycle 42 1.31387
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.31297
GRIK2 glutamate receptor, ionotropic, kainate 2 1.31297
ADM adrenomedullin 1.31267
CYBA cytochrome b-245, alpha polypeptide 1.31267
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.3103
DPP4 dipeptidyl-peptidase 4 1.30788
CCNG1 cyclin G1 1.3036
APOOL apolipoprotein O-like 1.30026
ABHD14B abhydrolase domain containing 14B 1.29996
TBX21 T-box 21 1.29996
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.29564
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 1.2941
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 1.2941
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 1.29348
KRT8 keratin 8, type II 1.29256
GEM GTP binding protein overexpressed in skeletal muscle 1.2898
FSHB follicle stimulating hormone, beta polypeptide 1.28919
ATF3 activating transcription factor 3 1.28765
ENC1 ectodermal-neural cortex 1 (with BTB domain) 1.28734
CPN1 carboxypeptidase N, polypeptide 1 1.28703
GAMT guanidinoacetate N-methyltransferase 1.28579
DUSP10 dual specificity phosphatase 10 1.28579
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.28395
HSPA8 heat shock 70kDa protein 8 1.28241
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.2818
KLF4 Kruppel-like factor 4 (gut) 1.27875
BAK1 BCL2-antagonist/killer 1 1.27751
FOXO1 forkhead box O1 1.27595
CD36 CD36 molecule (thrombospondin receptor) 1.27595
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 1.27409
ALPL alkaline phosphatase, liver/bone/kidney 1.27347
G6PD glucose-6-phosphate dehydrogenase 1.27101
RTN4 reticulon 4 1.27039
CRYAB crystallin, alpha B 1.26732
ATF5 activating transcription factor 5 1.26638
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 1.26545
CHGA chromogranin A 1.26359
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.26359
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 1.26267
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 1.26267
LMNA lamin A/C 1.26267
FGF2 fibroblast growth factor 2 (basic) 1.2599
CNOT7 CCR4-NOT transcription complex, subunit 7 1.25899
CD151 CD151 molecule (Raph blood group) 1.25807
LAMC2 laminin, gamma 2 1.25557
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 1.25245
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 1.25245
RHOB ras homolog family member B 1.25214
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.2475
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.24718
TAGLN transgelin 1.24718
C3 complement component 3 1.2456
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.24433
PGD phosphogluconate dehydrogenase 1.24433
CASP12 caspase 12 (gene/pseudogene) 1.24433
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 1.24181
MUT methylmalonyl CoA mutase 1.24181
ABHD2 abhydrolase domain containing 2 1.24181
CTSL cathepsin L 1.24181
DDIT4 DNA-damage-inducible transcript 4 1.23993
STAR steroidogenic acute regulatory protein 1.23993
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.23837
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 1.23712
IL1R1 interleukin 1 receptor, type I 1.23456
CTSD cathepsin D 1.23424
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.23201
EGR2 early growth response 2 1.23201
SFXN1 sideroflexin 1 1.23137
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 1.23137
IFI44 interferon-induced protein 44 1.23137
SST somatostatin 1.23106
IGFBP5 insulin-like growth factor binding protein 5 1.22948
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.22853
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.2279
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.22727
PDGFA platelet-derived growth factor alpha polypeptide 1.22727
ACSS2 acyl-CoA synthetase short-chain family member 2 1.22632
SLC46A1 solute carrier family 46 (folate transporter), member 1 1.22632
PPARD peroxisome proliferator-activated receptor delta 1.22242
POU2F1 POU class 2 homeobox 1 1.22145
CRIP1 cysteine-rich protein 1 (intestinal) 1.22145
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 1.2208
ANXA4 annexin A4 1.2208
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.21759
PLA1A phospholipase A1 member A 1.21663
ACSL6 acyl-CoA synthetase long-chain family member 6 1.21663
NFX1 nuclear transcription factor, X-box binding 1 1.21534
PHF1 PHD finger protein 1 1.21534
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.21435
NGFR nerve growth factor receptor 1.21435
RAN RAN, member RAS oncogene family 1.21435
RAD50 RAD50 homolog (S. cerevisiae) 1.21435
PDGFB platelet-derived growth factor beta polypeptide 1.21271
ARG1 arginase 1 1.21043
NOS1 nitric oxide synthase 1 (neuronal) 1.20848
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 1.20816
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 1.20751
RRAS2 related RAS viral (r-ras) oncogene homolog 2 1.20687
S100A8 S100 calcium binding protein A8 1.20361
CA2 carbonic anhydrase II 1.20361
CCNA2 cyclin A2 1.20328
PGRMC1 progesterone receptor membrane component 1 1.20229
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.20163
FOSL2 FOS-like antigen 2 1.2013
PLG plasminogen 1.2013
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.199
APAF1 apoptotic peptidase activating factor 1 1.199
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.19835
SLCO2A1 solute carrier organic anion transporter family, member 2A1 1.1977
F8 coagulation factor VIII, procoagulant component 1.1977
DCXR dicarbonyl/L-xylulose reductase 1.1977
RPL13 ribosomal protein L13 1.1977
ANXA2 annexin A2 1.19672
BBC3 BCL2 binding component 3 1.19672
GCLM glutamate-cysteine ligase, modifier subunit 1.19509
NR1D1 nuclear receptor subfamily 1, group D, member 1 1.19509
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.19312
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 1.19312
NFE2L2 nuclear factor, erythroid 2-like 2 1.18849
CAMK4 calcium/calmodulin-dependent protein kinase IV 1.18849
ACACA acetyl-CoA carboxylase alpha 1.18783
PRKCA protein kinase C, alpha 1.18751
MARCKS myristoylated alanine-rich protein kinase C substrate 1.1862
ERN1 endoplasmic reticulum to nucleus signaling 1 1.1862
BMP2K BMP2 inducible kinase 1.18489
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 1.18456
IFITM1 interferon induced transmembrane protein 1 1.18424
CFI complement factor I 1.18424
FMO2 flavin containing monooxygenase 2 (non-functional) 1.18424
FN1 fibronectin 1 1.18391
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.18326
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.18326
SCNN1A sodium channel, non voltage gated 1 alpha subunit 1.18326
HPRT1 hypoxanthine phosphoribosyltransferase 1 1.18126
JAK1 Janus kinase 1 1.18026
PPL periplakin 1.17993
SOCS5 suppressor of cytokine signaling 5 1.17794
MAP2K1 mitogen-activated protein kinase kinase 1 1.17761
MKI67 marker of proliferation Ki-67 1.17596
CCND3 cyclin D3 1.17268
NUMBL numb homolog (Drosophila)-like 1.17134
PPAN peter pan homolog (Drosophila) 1.17101
MMP1 matrix metallopeptidase 1 1.17101
SLC35A4 solute carrier family 35, member A4 1.17067
SOCS7 suppressor of cytokine signaling 7 1.17067
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9 1.17067
EGFL6 EGF-like-domain, multiple 6 1.17067
VLDLR very low density lipoprotein receptor 1.16866
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 1.16866
TMEM97 transmembrane protein 97 1.167
SRM spermidine synthase 1.167
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 1.167
CCNG2 cyclin G2 1.16567
TNC tenascin C 1.16567
EDNRB endothelin receptor type B 1.16434
TNRC6A trinucleotide repeat containing 6A 1.16434
SRSF1 serine/arginine-rich splicing factor 1 1.16302
CALB1 calbindin 1, 28kDa 1.16302
PLAT plasminogen activator, tissue 1.16302
H2AFX H2A histone family, member X 1.16302
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.16302
GRIA2 glutamate receptor, ionotropic, AMPA 2 1.16302
BAD BCL2-associated agonist of cell death 1.16137
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.16104
DRD1 dopamine receptor D1 1.16001
CSK c-src tyrosine kinase 1.15899
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.15899
ANGEL2 angel homolog 2 (Drosophila) 1.15831
CST7 cystatin F (leukocystatin) 1.15831
TLR4 toll-like receptor 4 1.15797
SRPRB signal recognition particle receptor, B subunit 1.15763
WDR26 WD repeat domain 26 1.15763
S100A4 S100 calcium binding protein A4 1.15729
S100A6 S100 calcium binding protein A6 1.15729
PTPRC protein tyrosine phosphatase, receptor type, C 1.15492
STAT1 signal transducer and activator of transcription 1, 91kDa 1.15492
PDE4B phosphodiesterase 4B, cAMP-specific 1.15458
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 1.15458
ADORA2A adenosine A2a receptor 1.15189
BTG1 B-cell translocation gene 1, anti-proliferative 1.15189
AQP2 aquaporin 2 (collecting duct) 1.15156
NDUFS5 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) 1.15156
EPS8L2 EPS8-like 2 1.15122
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1.15122
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 1.15089
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.15089
SGK1 serum/glucocorticoid regulated kinase 1 1.14989
PLIN2 perilipin 2 1.14919
IL3 interleukin 3 1.14713
TEK TEK tyrosine kinase, endothelial 1.14713
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 1.14713
PHKB phosphorylase kinase, beta 1.1461
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 1.14507
HMGN1 high mobility group nucleosome binding domain 1 1.14507
ENO1 enolase 1, (alpha) 1.14404
XBP1 X-box binding protein 1 1.14404
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 1.1437
MGP matrix Gla protein 1.1437
MFGE8 milk fat globule-EGF factor 8 protein 1.14302
E2F1 E2F transcription factor 1 1.142
ERBB2 erb-b2 receptor tyrosine kinase 2 1.142
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 1.14098
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.14098
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.14098
ALAS2 5'-aminolevulinate synthase 2 1.13929
FGA fibrinogen alpha chain 1.13862
MSMO1 methylsterol monooxygenase 1 1.13827
LGALS1 lectin, galactoside-binding, soluble, 1 1.13827
IGFBP1 insulin-like growth factor binding protein 1 1.13793
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.13793
DPYD dihydropyrimidine dehydrogenase 1.13586
MUC1 mucin 1, cell surface associated 1.13552
PNPLA2 patatin-like phospholipase domain containing 2 1.13552
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 1.13518
THRA thyroid hormone receptor, alpha 1.13313
ACOT4 acyl-CoA thioesterase 4 1.13279
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 1.13279
CPT1A carnitine palmitoyltransferase 1A (liver) 1.13041
PGAM1 phosphoglycerate mutase 1 (brain) 1.12805
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 1.12703
FMO1 flavin containing monooxygenase 1 1.12564
CD44 CD44 molecule (Indian blood group) 1.12461
SLCO2B1 solute carrier organic anion transporter family, member 2B1 1.12461
BIK BCL2-interacting killer (apoptosis-inducing) 1.12461
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 1.12426
HMGB1 high mobility group box 1 1.12288
F2R coagulation factor II (thrombin) receptor 1.12288
CDK4 cyclin-dependent kinase 4 1.12151
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.12117
TAC1 tachykinin, precursor 1 1.11843
FKBP5 FK506 binding protein 5 1.11809
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.11809
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 1.11741
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 1.11741
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.11606
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 1.11571
DBT dihydrolipoamide branched chain transacylase E2 1.11571
MAG myelin associated glycoprotein 1.11571
OAT ornithine aminotransferase 1.11571
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 1.11536
POR P450 (cytochrome) oxidoreductase 1.1129
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.11081
POU5F1 POU class 5 homeobox 1 1.11046
FKBP1B FK506 binding protein 1B, 12.6 kDa 1.11046
FOXP3 forkhead box P3 1.11046
UFD1L ubiquitin fusion degradation 1 like (yeast) 1.11011
TMED2 transmembrane emp24 domain trafficking protein 2 1.11011
AVP arginine vasopressin 1.10838
FAAH fatty acid amide hydrolase 1.10699
MCM7 minichromosome maintenance complex component 7 1.10665
NT5E 5'-nucleotidase, ecto (CD73) 1.10665
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 1.10493
UBE2D2 ubiquitin-conjugating enzyme E2D 2 1.10493
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.10459
SPPL2A signal peptide peptidase like 2A 1.10388
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 1.10353
KLF6 Kruppel-like factor 6 1.10353
RBL2 retinoblastoma-like 2 1.10353
LCAT lecithin-cholesterol acyltransferase 1.10353
GFAP glial fibrillary acidic protein 1.10069
ISG15 ISG15 ubiquitin-like modifier 1.09998
ACOT1 acyl-CoA thioesterase 1 1.09998
C1QBP complement component 1, q subcomponent binding protein 1.09963
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 1.09963
C1R complement component 1, r subcomponent 1.09963
F2 coagulation factor II (thrombin) 1.09716
GATA4 GATA binding protein 4 1.09681
ADA adenosine deaminase 1.09646
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.09646
NEU2 sialidase 2 (cytosolic sialidase) 1.09436
ADCY5 adenylate cyclase 5 1.09436
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 1.09436
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 1.09436
ARRB1 arrestin, beta 1 1.09436
PRKD3 protein kinase D3 1.09436
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.09436
KCNK1 potassium channel, two pore domain subfamily K, member 1 1.09436
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 1.09401
CDK6 cyclin-dependent kinase 6 1.09401
ERRFI1 ERBB receptor feedback inhibitor 1 1.09332
CCNB1 cyclin B1 1.09297
PDGFRB platelet-derived growth factor receptor, beta polypeptide 1.09154
CST3 cystatin C 1.09011
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 1.09011
PROC protein C (inactivator of coagulation factors Va and VIIIa) 1.09011
VWF von Willebrand factor 1.09011
GBP1 guanylate binding protein 1, interferon-inducible 1.0894
ARID1A AT rich interactive domain 1A (SWI-like) 1.08904
GAB1 GRB2-associated binding protein 1 1.08904
VGF VGF nerve growth factor inducible 1.08904
CALR calreticulin 1.0869
TUBB tubulin, beta class I 1.08655
KLHL28 kelch-like family member 28 1.08549
MRPL2 mitochondrial ribosomal protein L2 1.08549
CUBN cubilin (intrinsic factor-cobalamin receptor) 1.08513
CLIC1 chloride intracellular channel 1 1.08407
STIP1 stress-induced phosphoprotein 1 1.08337
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.08337
LIPC lipase, hepatic 1.08337
FBP1 fructose-1,6-bisphosphatase 1 1.08337
RGS2 regulator of G-protein signaling 2 1.08231
CDK2 cyclin-dependent kinase 2 1.08091
GRIA1 glutamate receptor, ionotropic, AMPA 1 1.08055
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.08019
BCL6 B-cell CLL/lymphoma 6 1.08019
SMAD7 SMAD family member 7 1.08019
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.08019
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.07983
ASL argininosuccinate lyase 1.07911
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 1.07911
IFIH1 interferon induced with helicase C domain 1 1.07911
PCTP phosphatidylcholine transfer protein 1.07911
RAD51 RAD51 recombinase 1.07804
PENK proenkephalin 1.07804
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 1.07696
FADS1 fatty acid desaturase 1 1.07696
CD83 CD83 molecule 1.07696
TEX261 testis expressed 261 1.0766
SLC38A5 solute carrier family 38, member 5 1.07625
MOG myelin oligodendrocyte glycoprotein 1.07625
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.07553
NTF3 neurotrophin 3 1.07411
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 1.07411
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.07411
CALCA calcitonin-related polypeptide alpha 1.07163
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.07163
PTK2 protein tyrosine kinase 2 1.07128
PDIA6 protein disulfide isomerase family A, member 6 1.07093
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 1.06952
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.06952
TSHR thyroid stimulating hormone receptor 1.06952
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.06952
PCSK6 proprotein convertase subtilisin/kexin type 6 1.06952
CHL1 cell adhesion molecule L1-like 1.06808
PTHLH parathyroid hormone-like hormone 1.06771
WTAP Wilms tumor 1 associated protein 1.06771
UNC119 unc-119 homolog (C. elegans) 1.06771
TRAFD1 TRAF-type zinc finger domain containing 1 1.06771
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 1.06771
ALDOC aldolase C, fructose-bisphosphate 1.06771
ESR1 estrogen receptor 1 1.06734
KNG1 kininogen 1 1.06698
ANXA5 annexin A5 1.06479
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 1.06479
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.06479
CHUK conserved helix-loop-helix ubiquitous kinase 1.06479
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 1.06479
GCLC glutamate-cysteine ligase, catalytic subunit 1.06225
HAVCR1 hepatitis A virus cellular receptor 1 1.06188
GADD45B growth arrest and DNA-damage-inducible, beta 1.06044
MMP8 matrix metallopeptidase 8 1.06044
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12 1.06044
CCNL1 cyclin L1 1.06008
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.06008
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.06008
TG thyroglobulin 1.06008
DLAT dihydrolipoamide S-acetyltransferase 1.06008
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 1.06008
HRK harakiri, BCL2 interacting protein 1.06008
CSAD cysteine sulfinic acid decarboxylase 1.06008
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 1.06008
PGM1 phosphoglucomutase 1 1.06008
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 1.06008
HIGD1A HIG1 hypoxia inducible domain family, member 1A 1.06008
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 1.05972
ECE2 endothelin converting enzyme 2 1.059
TGFBR1 transforming growth factor, beta receptor 1 1.05573
CALM1 calmodulin 1 (phosphorylase kinase, delta) 1.05573
KRT7 keratin 7, type II 1.05535
PC pyruvate carboxylase 1.05535
LSP1 lymphocyte-specific protein 1 1.05535
GLDC glycine dehydrogenase (decarboxylating) 1.05535
GJB1 gap junction protein, beta 1, 32kDa 1.05274
PKLR pyruvate kinase, liver and RBC 1.05274
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.05274
GRN granulin 1.05237
DNMT1 DNA (cytosine-5-)-methyltransferase 1 1.05163
ANGPTL4 angiopoietin-like 4 1.05163
JUNB jun B proto-oncogene 1.05163
RPL26 ribosomal protein L26 1.05163
C2CD2 C2 calcium-dependent domain containing 2 1.05126
SRR serine racemase 1.05126
TTL tubulin tyrosine ligase 1.05126
ASPA aspartoacylase 1.05089
STAT2 signal transducer and activator of transcription 2, 113kDa 1.05089
VDAC1 voltage-dependent anion channel 1 1.04978
CSF1 colony stimulating factor 1 (macrophage) 1.04978
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.04978
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.04868
CCL5 chemokine (C-C motif) ligand 5 1.04794
CX3CL1 chemokine (C-X3-C motif) ligand 1 1.04684
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 1.04684
LTF lactotransferrin 1.04684
GDF15 growth differentiation factor 15 1.04684
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit 1.04684
PXN paxillin 1.04647
EIF4A2 eukaryotic translation initiation factor 4A2 1.04647
ISYNA1 inositol-3-phosphate synthase 1 1.04647
PRKACB protein kinase, cAMP-dependent, catalytic, beta 1.04647
NR3C2 nuclear receptor subfamily 3, group C, member 2 1.04389
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 1.04389
PLCL1 phospholipase C-like 1 1.04389
VPS13B vacuolar protein sorting 13 homolog B (yeast) 1.04352
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 1.04352
COPG1 coatomer protein complex, subunit gamma 1 1.04352
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.04201
IRF9 interferon regulatory factor 9 1.04163
RAMP1 receptor (G protein-coupled) activity modifying protein 1 1.04163
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 1.03901
GPX3 glutathione peroxidase 3 1.03901
CHEK2 checkpoint kinase 2 1.03901
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 1.03789
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.03752
TPI1 triosephosphate isomerase 1 1.0353
RYR2 ryanodine receptor 2 (cardiac) 1.03345
IER5 immediate early response 5 1.03308
H3F3B H3 histone, family 3B (H3.3B) 1.03308
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.03308
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 1.03271
DHCR24 24-dehydrocholesterol reductase 1.03235
UNG uracil-DNA glycosylase 1.02933
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.02933
PLSCR1 phospholipid scramblase 1 1.02896
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.02896
REST RE1-silencing transcription factor 1.02858
MAP1A microtubule-associated protein 1A 1.02858
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.02858
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.02858
BET1L Bet1 golgi vesicular membrane trafficking protein-like 1.02858
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit 1.02821
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.02671
OLFM3 olfactomedin 3 1.02634
TCF19 transcription factor 19 1.02485
USP2 ubiquitin specific peptidase 2 1.02485
ADK adenosine kinase 1.02485
RAB6A RAB6A, member RAS oncogene family 1.02151
CLINT1 clathrin interactor 1 1.02151
AHR aryl hydrocarbon receptor 1.02151
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 1.02114
CAMK2D calcium/calmodulin-dependent protein kinase II delta 1.02077
SLC16A6 solute carrier family 16, member 6 1.0204
HNF4A hepatocyte nuclear factor 4, alpha 1.01852
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 1.01663
AHCY adenosylhomocysteinase 1.01663
TFF3 trefoil factor 3 (intestinal) 1.01663
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.01663
GCG glucagon 1.01625
ELOVL6 ELOVL fatty acid elongase 6 1.01587
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 1.01587
CREM cAMP responsive element modulator 1.01587
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 1.01549
DAPK2 death-associated protein kinase 2 1.01437
MYADM myeloid-associated differentiation marker 1.01437
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 1.01437
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 1.01437
ADNP activity-dependent neuroprotector homeobox 1.01437
TMBIM1 transmembrane BAX inhibitor motif containing 1 1.01437
RNF145 ring finger protein 145 1.01437
HPCAL4 hippocalcin like 4 1.01437
EPC1 enhancer of polycomb homolog 1 (Drosophila) 1.01399
G0S2 G0/G1 switch 2 1.01324
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.01324
ITGB5 integrin, beta 5 1.01249
PRR18 proline rich 18 1.01174
MAPT microtubule-associated protein tau 1.01137
CHEK1 checkpoint kinase 1 1.01137
ATF2 activating transcription factor 2 1.01062