Vascular Diseases Gene Set

Dataset HuGE Navigator Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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Genes

117 genes associated with the Vascular Diseases phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACE angiotensin I converting enzyme
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AHSG alpha-2-HS-glycoprotein
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
ARMS2 age-related maculopathy susceptibility 2
C10ORF10 chromosome 10 open reading frame 10
C2 complement component 2
C3 complement component 3
C5 complement component 5
C7 complement component 7
CBS cystathionine-beta-synthase
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CETP cholesteryl ester transfer protein, plasma
CFB complement factor B
CFH complement factor H
CFI complement factor I
CMA1 chymase 1, mast cell
CREBBP CREB binding protein
CRP C-reactive protein, pentraxin-related
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
EDN1 endothelin 1
EPO erythropoietin
ERCC6 excision repair cross-complementation group 6
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
F13B coagulation factor XIII, B polypeptide
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FBLN5 fibulin 5
FBN1 fibrillin 1
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FOXC2 forkhead box C2
GCH1 GTP cyclohydrolase 1
GJA4 gap junction protein, alpha 4, 37kDa
GLO1 glyoxalase I
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP6 glycoprotein VI (platelet)
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HFE hemochromatosis
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMCN1 hemicentin 1
IFNG interferon, gamma
IL10 interleukin 10
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL6 interleukin 6
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
KDR kinase insert domain receptor
LDLR low density lipoprotein receptor
LIPC lipase, hepatic
LPL lipoprotein lipase
MBL2 mannose-binding lectin (protein C) 2, soluble
MEFV Mediterranean fever
MMP3 matrix metallopeptidase 3
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
NGFR nerve growth factor receptor
NOS3 nitric oxide synthase 3 (endothelial cell)
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PCSK9 proprotein convertase subtilisin/kexin type 9
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PON1 paraoxonase 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SOD1 superoxide dismutase 1, soluble
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TP53 tumor protein p53
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VKORC1 vitamin K epoxide reductase complex, subunit 1
VLDLR very low density lipoprotein receptor
VTN vitronectin
VWF von Willebrand factor