Valproic Acid Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem. (Chemical Entities of Biological Interest Ontology, CHEBI_39867)
External Link http://ctdbase.org/detail.go?type=chem&acc=D014635
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Genes

137 genes/proteins interacting with the chemical Valproic Acid from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB1 adrenoceptor beta 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
BAG1 BCL2-associated athanogene
BAX BCL2-associated X protein
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L2 BCL2-like 2
BDNF brain-derived neurotrophic factor
BID BH3 interacting domain death agonist
BIRC5 baculoviral IAP repeat containing 5
CALB1 calbindin 1, 28kDa
CALR calreticulin
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CAT catalase
CCNA1 cyclin A1
CCND1 cyclin D1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CFB complement factor B
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CREB1 cAMP responsive element binding protein 1
CTAG1B cancer/testis antigen 1B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DHFR dihydrofolate reductase
DPPA2 developmental pluripotency associated 2
DRD2 dopamine receptor D2
EGF epidermal growth factor
ELK1 ELK1, member of ETS oncogene family
ENO2 enolase 2 (gamma, neuronal)
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F13A1 coagulation factor XIII, A1 polypeptide
FABP2 fatty acid binding protein 2, intestinal
FAS Fas cell surface death receptor
FOLR2 folate receptor 2 (fetal)
FOS FBJ murine osteosarcoma viral oncogene homolog
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GATA3 GATA binding protein 3
GFAP glial fibrillary acidic protein
GLI3 GLI family zinc finger 3
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIK2 glutamate receptor, ionotropic, kainate 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC7 histone deacetylase 7
HIST3H3 histone cluster 3, H3
HIST4H4 histone cluster 4, H4
HOXA2 homeobox A2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IFNG interferon, gamma
IL10 interleukin 10
IL5 interleukin 5
IL6 interleukin 6
JUN jun proto-oncogene
LHB luteinizing hormone beta polypeptide
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCL1 myeloid cell leukemia 1
MYB v-myb avian myeloblastosis viral oncogene homolog
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEFH neurofilament, heavy polypeptide
NEFM neurofilament, medium polypeptide
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTF3 neurotrophin 3
PARP1 poly (ADP-ribose) polymerase 1
PAX3 paired box 3
PDE4A phosphodiesterase 4A, cAMP-specific
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
POLG polymerase (DNA directed), gamma
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELN reelin
SIX1 SIX homeobox 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMN2 survival of motor neuron 2, centromeric
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX17 SRY (sex determining region Y)-box 17
SP1 Sp1 transcription factor
STAR steroidogenic acute regulatory protein
TAC1 tachykinin, precursor 1
TH tyrosine hydroxylase
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP63 tumor protein p63
TRADD TNFRSF1A-associated via death domain
TUBB3 tubulin, beta 3 class III
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIM vimentin
VLDLR very low density lipoprotein receptor
WFS1 Wolfram syndrome 1 (wolframin)
WNT1 wingless-type MMTV integration site family, member 1
WNT2 wingless-type MMTV integration site family member 2
ZEB1 zinc finger E-box binding homeobox 1