Uterine leiomyoma_Uterus_GSE2725 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2725
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Genes

600 genes differentially expressed during Uterine leiomyoma_Uterus_GSE2725 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
HLX H2.0-like homeobox 3.49374
FAM102A family with sequence similarity 102, member A 3.35747
BABAM1 BRISC and BRCA1 A complex member 1 3.29973
PDF peptide deformylase (mitochondrial) 3.26833
KLHL4 kelch-like family member 4 3.1368
EIF3B eukaryotic translation initiation factor 3, subunit B 3.11781
INF2 inverted formin, FH2 and WH2 domain containing 3.08705
ZNF34 zinc finger protein 34 3.07021
MRPS18A mitochondrial ribosomal protein S18A 3.01231
SDCCAG3 serologically defined colon cancer antigen 3 2.9364
ERCC8 excision repair cross-complementation group 8 2.89052
C6ORF25 chromosome 6 open reading frame 25 2.74377
FAIM2 Fas apoptotic inhibitory molecule 2 2.72057
NXPH4 neurexophilin 4 2.71887
FASTK Fas-activated serine/threonine kinase 2.71627
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.67439
SSNA1 Sjogren syndrome nuclear autoantigen 1 2.65235
PLXNA1 plexin A1 2.61098
NAP1L4 nucleosome assembly protein 1-like 4 2.59514
AP3S1 adaptor-related protein complex 3, sigma 1 subunit 2.5785
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 2.57757
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.56731
HPS6 Hermansky-Pudlak syndrome 6 2.55436
KXD1 KxDL motif containing 1 2.54694
UNC45A unc-45 homolog A (C. elegans) 2.53709
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 2.5321
VSNL1 visinin-like 1 2.52926
MOSPD3 motile sperm domain containing 3 2.51716
DOK5 docking protein 5 2.50576
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.49386
SYMPK symplekin 2.47827
TRAPPC3 trafficking protein particle complex 3 2.45618
TCTE1 t-complex-associated-testis-expressed 1 2.42606
TSC22D4 TSC22 domain family, member 4 2.39948
ERVH-6 endogenous retrovirus group H, member 6 2.38411
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 2.38048
SCARA3 scavenger receptor class A, member 3 2.36684
SHOX2 short stature homeobox 2 2.36595
SBF1 SET binding factor 1 2.35854
TCEB1P3 transcription elongation factor B (SIII), polypeptide 1 pseudogene 3 2.34682
DES desmin 2.32851
SMG5 SMG5 nonsense mediated mRNA decay factor 2.31129
GOLGA1 golgin A1 2.29225
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 2.28458
GAB2 GRB2-associated binding protein 2 2.27479
OAZ1 ornithine decarboxylase antizyme 1 2.26515
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2.25806
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 2.24261
SH2B1 SH2B adaptor protein 1 2.24124
DLG3 discs, large homolog 3 (Drosophila) 2.22992
TRIM21 tripartite motif containing 21 2.22805
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) 2.20091
IL13 interleukin 13 2.1992
GATA6 GATA binding protein 6 2.19015
ADRM1 adhesion regulating molecule 1 2.18822
PDGFC platelet derived growth factor C 2.18252
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 2.16842
SLC12A9 solute carrier family 12, member 9 2.16501
DMWD dystrophia myotonica, WD repeat containing 2.12849
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.12208
BOP1 block of proliferation 1 2.11969
TMEM104 transmembrane protein 104 2.11835
GLP1R glucagon-like peptide 1 receptor 2.10214
BICC1 BicC family RNA binding protein 1 2.08734
TMC7 transmembrane channel-like 7 2.07269
RANGAP1 Ran GTPase activating protein 1 2.05935
BBS10 Bardet-Biedl syndrome 10 2.05557
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 2.05539
FBRS fibrosin 2.05044
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 2.04843
TRMT61A tRNA methyltransferase 61A 2.03578
SLC4A2 solute carrier family 4 (anion exchanger), member 2 2.02746
TAOK3 TAO kinase 3 2.02678
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.02594
TNR tenascin R 2.01995
CCDC22 coiled-coil domain containing 22 2.01606
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 2.0127
MAP3K10 mitogen-activated protein kinase kinase kinase 10 1.98982
BIN3 bridging integrator 3 1.98447
EPHB4 EPH receptor B4 1.9821
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 1.98085
HMBS hydroxymethylbilane synthase 1.98048
ARF3 ADP-ribosylation factor 3 1.97479
GPR137 G protein-coupled receptor 137 1.9732
EMD emerin 1.96427
THBS2 thrombospondin 2 1.95807
DNPEP aspartyl aminopeptidase 1.95713
NOD1 nucleotide-binding oligomerization domain containing 1 1.95387
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 1.95065
QRICH1 glutamine-rich 1 1.94578
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 1.94396
SAC3D1 SAC3 domain containing 1 1.93693
PDK3 pyruvate dehydrogenase kinase, isozyme 3 1.93505
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 1.91692
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 1.91435
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.91115
PHYH phytanoyl-CoA 2-hydroxylase 1.90996
ADORA1 adenosine A1 receptor 1.90894
PHC2 polyhomeotic homolog 2 (Drosophila) 1.90399
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 1.89662
TFIP11 tuftelin interacting protein 11 1.89613
HIGD1B HIG1 hypoxia inducible domain family, member 1B 1.8931
SOX4 SRY (sex determining region Y)-box 4 1.89231
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 1.8823
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.87933
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.87022
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 1.86768
ENOPH1 enolase-phosphatase 1 1.86482
NBEA neurobeachin 1.86268
MATN2 matrilin 2 1.85833
FBXL7 F-box and leucine-rich repeat protein 7 1.85753
E2F4 E2F transcription factor 4, p107/p130-binding 1.85633
FAM89B family with sequence similarity 89, member B 1.8543
NEUROD2 neuronal differentiation 2 1.85176
ARHGAP24 Rho GTPase activating protein 24 1.84775
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) 1.84596
HMOX1 heme oxygenase 1 1.83699
PLSCR1 phospholipid scramblase 1 1.83219
STX10 syntaxin 10 1.83018
MUS81 MUS81 structure-specific endonuclease subunit 1.82949
LOC139061 plasmolipin pseudogene 1.82461
CDC34 cell division cycle 34 1.81421
PDE4A phosphodiesterase 4A, cAMP-specific 1.80855
CDK4 cyclin-dependent kinase 4 1.805
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 1.80202
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 1.7998
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.79963
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 1.79774
HNF4A hepatocyte nuclear factor 4, alpha 1.7949
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 1.79321
WDR46 WD repeat domain 46 1.79006
CLP1 cleavage and polyadenylation factor I subunit 1 1.78788
TRAM2 translocation associated membrane protein 2 1.78157
DGKZ diacylglycerol kinase, zeta 1.7697
BAK1 BCL2-antagonist/killer 1 1.76543
RAB31 RAB31, member RAS oncogene family 1.76288
NCAPH2 non-SMC condensin II complex, subunit H2 1.75781
TBL3 transducin (beta)-like 3 1.74988
G6PD glucose-6-phosphate dehydrogenase 1.74825
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.74542
DOLK dolichol kinase 1.74473
CD63 CD63 molecule 1.74251
PML promyelocytic leukemia 1.74199
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 1.74178
RBM26 RNA binding motif protein 26 1.73513
CRTC3 CREB regulated transcription coactivator 3 1.72983
URM1 ubiquitin related modifier 1 1.72844
YAP1 Yes-associated protein 1 1.72531
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) 1.72449
SPRR1A small proline-rich protein 1A 1.72012
CBX6 chromobox homolog 6 1.71869
PLEKHO1 pleckstrin homology domain containing, family O member 1 1.71686
CCDC85B coiled-coil domain containing 85B 1.714
RNGTT RNA guanylyltransferase and 5'-phosphatase 1.71356
BAX BCL2-associated X protein 1.70783
ADO 2-aminoethanethiol (cysteamine) dioxygenase 1.70767
TIAF1 TGFB1-induced anti-apoptotic factor 1 1.70723
IPO9 importin 9 1.69822
C11ORF68 chromosome 11 open reading frame 68 1.69528
LOC440792 proline dehydrogenase (oxidase) 1 pseudogene 1.69427
HDAC9 histone deacetylase 9 1.69258
EMX1 empty spiracles homeobox 1 1.68025
CHEK1 checkpoint kinase 1 1.6774
MAP2K5 mitogen-activated protein kinase kinase 5 1.67205
ZNF512B zinc finger protein 512B 1.66145
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2 1.6589
PGLYRP1 peptidoglycan recognition protein 1 1.65783
PPP1R37 protein phosphatase 1, regulatory subunit 37 1.65697
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.65201
PVRL3 poliovirus receptor-related 3 1.64753
RBM17 RNA binding motif protein 17 1.64439
C3ORF18 chromosome 3 open reading frame 18 1.64409
APC2 adenomatosis polyposis coli 2 1.64389
LYPLA2 lysophospholipase II 1.64367
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 1.64178
RTN2 reticulon 2 1.64141
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 1.63618
PRPF19 pre-mRNA processing factor 19 1.63545
LPCAT1 lysophosphatidylcholine acyltransferase 1 1.62987
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 1.62976
ACAT1 acetyl-CoA acetyltransferase 1 1.62447
CLDN1 claudin 1 1.62297
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 1.62236
PRDM8 PR domain containing 8 1.61286
PQLC2 PQ loop repeat containing 2 1.61082
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 1.60829
IL36G interleukin 36, gamma 1.60827
PRAMEF10 PRAME family member 10 1.60398
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 1.60304
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 1.59958
SH3GL1 SH3-domain GRB2-like 1 1.5993
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.59636
TRIM28 tripartite motif containing 28 1.59501
CLCF1 cardiotrophin-like cytokine factor 1 1.59415
BRD7P3 bromodomain containing 7 pseudogene 3 1.59385
AAMP angio-associated, migratory cell protein 1.59185
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 1.59048
CENPB centromere protein B, 80kDa 1.58597
MYH15 myosin, heavy chain 15 1.58393
ALAS1 5'-aminolevulinate synthase 1 1.58084
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 1.57882
BAHD1 bromo adjacent homology domain containing 1 1.57619
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 1.5722
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 1.57201
CHTF18 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) 1.56147
RAP1B RAP1B, member of RAS oncogene family 1.56005
C11ORF58 chromosome 11 open reading frame 58 1.55893
GPKOW G patch domain and KOW motifs 1.55359
KIAA1107 KIAA1107 1.54374
CCNF cyclin F 1.54362
TCEA1 transcription elongation factor A (SII), 1 1.54358
FSCN1 fascin actin-bundling protein 1 1.53424
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 1.53417
OSBPL8 oxysterol binding protein-like 8 1.5328
PLS3 plastin 3 1.53278
TBX2 T-box 2 1.53232
ECSIT ECSIT signalling integrator 1.53219
RAB22A RAB22A, member RAS oncogene family 1.52786
PTPRR protein tyrosine phosphatase, receptor type, R 1.52759
CLCN7 chloride channel, voltage-sensitive 7 1.52676
NR2F6 nuclear receptor subfamily 2, group F, member 6 1.52359
AKAP13 A kinase (PRKA) anchor protein 13 1.52044
GTPBP1 GTP binding protein 1 1.51947
CHI3L2 chitinase 3-like 2 1.51934
GPR4 G protein-coupled receptor 4 1.51673
FHOD1 formin homology 2 domain containing 1 1.51642
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 1.51447
KPNA6 karyopherin alpha 6 (importin alpha 7) 1.51197
MAP2K2 mitogen-activated protein kinase kinase 2 1.50508
CDK11A cyclin-dependent kinase 11A 1.50449
CD226 CD226 molecule 1.49913
KLHL22 kelch-like family member 22 1.49876
FAM53B family with sequence similarity 53, member B 1.49121
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.48941
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 1.48872
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.48754
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 1.48704
PUM2 pumilio RNA-binding family member 2 1.48681
SRI sorcin 1.48618
MEIS2 Meis homeobox 2 1.48576
FOXL1 forkhead box L1 1.48576
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 1.48403
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 1.48105
UBAP2L ubiquitin associated protein 2-like 1.48069
NECAB3 N-terminal EF-hand calcium binding protein 3 1.48063
ACSM5 acyl-CoA synthetase medium-chain family member 5 1.48029
GBP1 guanylate binding protein 1, interferon-inducible 1.47944
TMEM38B transmembrane protein 38B 1.47385
LOC100420758 poly(A) binding protein, nuclear 1 pseudogene 1.47341
ASPN asporin 1.4732
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 1.47248
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 1.47023
OR3A2 olfactory receptor, family 3, subfamily A, member 2 1.47014
OLFM1 olfactomedin 1 1.46987
LAGE3 L antigen family, member 3 1.4621
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 1.46176
TXLNG taxilin gamma 1.45913
HRAS Harvey rat sarcoma viral oncogene homolog 1.45875
CXXC1 CXXC finger protein 1 1.45844
CXORF56 chromosome X open reading frame 56 1.45823
GNPDA1 glucosamine-6-phosphate deaminase 1 1.45805
IL17RC interleukin 17 receptor C 1.45738
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 1.45408
VDAC3 voltage-dependent anion channel 3 1.4534
MED22 mediator complex subunit 22 1.45079
WIPI2 WD repeat domain, phosphoinositide interacting 2 1.44964
CRMP1 collapsin response mediator protein 1 1.44872
GRIP2 glutamate receptor interacting protein 2 1.44803
PGC progastricsin (pepsinogen C) 1.44684
KLF1 Kruppel-like factor 1 (erythroid) 1.44499
YARS tyrosyl-tRNA synthetase 1.44452
R3HCC1 R3H domain and coiled-coil containing 1 1.44263
SF3B2 splicing factor 3b, subunit 2, 145kDa 1.44103
CYHR1 cysteine/histidine-rich 1 1.43984
MED15 mediator complex subunit 15 1.4382
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 1.43796
RHOT1 ras homolog family member T1 1.43622
NDRG3 NDRG family member 3 1.43614
GTF2IRD1 GTF2I repeat domain containing 1 1.43588
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 1.4357
BRD3 bromodomain containing 3 1.43563
FAM162A family with sequence similarity 162, member A 1.43076
COL5A2 collagen, type V, alpha 2 1.43029
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 1.42602
HIPK2 homeodomain interacting protein kinase 2 1.42429
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 1.42316
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 1.42277
RARA retinoic acid receptor, alpha 1.42078
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.41969
ACHE acetylcholinesterase (Yt blood group) 1.41928
PDCD11 programmed cell death 11 1.41914
EEF2 eukaryotic translation elongation factor 2 1.41724
TNNI1 troponin I type 1 (skeletal, slow) 1.41704
ACVR2A activin A receptor, type IIA 1.41514
PCIF1 PDX1 C-terminal inhibiting factor 1 1.41381
SRRT serrate, RNA effector molecule 1.41321
MYO9B myosin IXB 1.4132
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 1.40626
GNL1 guanine nucleotide binding protein-like 1 1.40393
PDX1 pancreatic and duodenal homeobox 1 1.4037

decreased expression

Symbol Name Standardized Value
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -3.55716
NTAN1 N-terminal asparagine amidase -2.97783
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -2.91227
SMAD7 SMAD family member 7 -2.89303
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.88169
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -2.86056
TRIM37 tripartite motif containing 37 -2.8567
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -2.78937
ALG8 ALG8, alpha-1,3-glucosyltransferase -2.78007
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.77815
CFI complement factor I -2.73001
ASXL2 additional sex combs like transcriptional regulator 2 -2.72274
LGALS8 lectin, galactoside-binding, soluble, 8 -2.67682
TMEM50A transmembrane protein 50A -2.65055
UBE4A ubiquitination factor E4A -2.6455
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -2.63312
MLH3 mutL homolog 3 -2.58453
CASP4 caspase 4, apoptosis-related cysteine peptidase -2.54537
CCNI cyclin I -2.49958
RAB27A RAB27A, member RAS oncogene family -2.48586
YLPM1 YLP motif containing 1 -2.48035
NR2F2 nuclear receptor subfamily 2, group F, member 2 -2.47922
RAI2 retinoic acid induced 2 -2.47574
NUP205 nucleoporin 205kDa -2.44473
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 -2.38674
MLX MLX, MAX dimerization protein -2.37736
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -2.35994
ZNF185 zinc finger protein 185 (LIM domain) -2.34969
GATA2 GATA binding protein 2 -2.31338
NEO1 neogenin 1 -2.2732
CALCOCO2 calcium binding and coiled-coil domain 2 -2.2628
MAK16 MAK16 homolog (S. cerevisiae) -2.25876
NIT2 nitrilase family, member 2 -2.24156
MRPS27 mitochondrial ribosomal protein S27 -2.23761
ZDHHC6 zinc finger, DHHC-type containing 6 -2.23525
RNF38 ring finger protein 38 -2.23485
PODXL podocalyxin-like -2.21294
BTN3A3 butyrophilin, subfamily 3, member A3 -2.20888
FAM149A family with sequence similarity 149, member A -2.19541
TMEM39A transmembrane protein 39A -2.18939
CCDC109B coiled-coil domain containing 109B -2.18067
MYO5C myosin VC -2.18066
IFFO2 intermediate filament family orphan 2 -2.1677
ALS2CL ALS2 C-terminal like -2.16613
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.15496
STX2 syntaxin 2 -2.12574
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 -2.12497
SRPX sushi-repeat containing protein, X-linked -2.11822
ARL4A ADP-ribosylation factor-like 4A -2.11653
TMEM62 transmembrane protein 62 -2.113
PCSK5 proprotein convertase subtilisin/kexin type 5 -2.11071
CBX5 chromobox homolog 5 -2.10727
SMYD2 SET and MYND domain containing 2 -2.10366
RGN regucalcin -2.07901
CCDC59 coiled-coil domain containing 59 -2.07274
GORASP1 golgi reassembly stacking protein 1, 65kDa -2.06451
TNXB tenascin XB -2.06396
MANSC1 MANSC domain containing 1 -2.0607
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -2.05098
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -2.04143
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -2.04021
FAM65B family with sequence similarity 65, member B -2.0287
SHROOM2 shroom family member 2 -1.99062
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.98577
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 -1.98552
EXT2 exostosin glycosyltransferase 2 -1.97676
TEX2 testis expressed 2 -1.96171
GOLGA5 golgin A5 -1.9588
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -1.95273
ICA1 islet cell autoantigen 1, 69kDa -1.94588
KCTD9 potassium channel tetramerization domain containing 9 -1.94494
ECD ecdysoneless homolog (Drosophila) -1.94298
PITPNB phosphatidylinositol transfer protein, beta -1.93699
PCDH9 protocadherin 9 -1.93554
ERCC4 excision repair cross-complementation group 4 -1.93161
TXNL4A thioredoxin-like 4A -1.92513
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -1.92264
PSPN persephin -1.92223
RNF4 ring finger protein 4 -1.91558
TMEM41B transmembrane protein 41B -1.91344
PARP4 poly (ADP-ribose) polymerase family, member 4 -1.90186
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) -1.89096
ZNF467 zinc finger protein 467 -1.89049
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 -1.88291
CCDC47 coiled-coil domain containing 47 -1.86707
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -1.85556
HOXB7 homeobox B7 -1.84949
CST3 cystatin C -1.84747
HEBP1 heme binding protein 1 -1.847
THAP10 THAP domain containing 10 -1.84598
SPG11 spastic paraplegia 11 (autosomal recessive) -1.82535
CALML4 calmodulin-like 4 -1.82377
TM2D3 TM2 domain containing 3 -1.81874
MOAP1 modulator of apoptosis 1 -1.81381
LAMB2 laminin, beta 2 (laminin S) -1.81093
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -1.80983
ETNK1 ethanolamine kinase 1 -1.80957
ARCN1 archain 1 -1.79989
CSNK2B casein kinase 2, beta polypeptide -1.79574
HCCS holocytochrome c synthase -1.79068
PHKB phosphorylase kinase, beta -1.79025
ADAM28 ADAM metallopeptidase domain 28 -1.78191
JAM2 junctional adhesion molecule 2 -1.78038
PDIA3 protein disulfide isomerase family A, member 3 -1.77582
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -1.77284
CCDC28A coiled-coil domain containing 28A -1.7716
DHRS3 dehydrogenase/reductase (SDR family) member 3 -1.76541
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -1.76383
ACPP acid phosphatase, prostate -1.76354
MPST mercaptopyruvate sulfurtransferase -1.7592
COPZ1 coatomer protein complex, subunit zeta 1 -1.75262
JTB jumping translocation breakpoint -1.7495
STEAP3 STEAP family member 3, metalloreductase -1.73557
STIM1 stromal interaction molecule 1 -1.73255
RPN2 ribophorin II -1.73254
MAN2B2 mannosidase, alpha, class 2B, member 2 -1.72585
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 -1.72091
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 -1.71469
ZHX2 zinc fingers and homeoboxes 2 -1.71455
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1 -1.71295
GCLC glutamate-cysteine ligase, catalytic subunit -1.7057
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 -1.70216
WISP2 WNT1 inducible signaling pathway protein 2 -1.69787
STAT4 signal transducer and activator of transcription 4 -1.69021
PCLO piccolo presynaptic cytomatrix protein -1.68314
LGTN ligatin -1.6831
ZNF706 zinc finger protein 706 -1.6808
INTS8 integrator complex subunit 8 -1.68066
AKAP7 A kinase (PRKA) anchor protein 7 -1.67977
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -1.66387
ERMP1 endoplasmic reticulum metallopeptidase 1 -1.66315
RAB5B RAB5B, member RAS oncogene family -1.65923
FAM45A family with sequence similarity 45, member A -1.65736
SH3BP2 SH3-domain binding protein 2 -1.65447
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -1.65301
LMO2 LIM domain only 2 (rhombotin-like 1) -1.64691
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -1.64538
DNAAF5 dynein, axonemal, assembly factor 5 -1.62961
GALT galactose-1-phosphate uridylyltransferase -1.62909
BTD biotinidase -1.62482
SLA Src-like-adaptor -1.62178
BRAP BRCA1 associated protein -1.62101
KIAA0556 KIAA0556 -1.6131
ZNF204P zinc finger protein 204, pseudogene -1.60966
HMGB2 high mobility group box 2 -1.60398
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase -1.60322
TUBB3 tubulin, beta 3 class III -1.5981
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -1.59608
TMEM59 transmembrane protein 59 -1.59561
LLGL2 lethal giant larvae homolog 2 (Drosophila) -1.59276
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) -1.58773
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -1.5867
HPS5 Hermansky-Pudlak syndrome 5 -1.5778
EMC7 ER membrane protein complex subunit 7 -1.57594
TPGS2 tubulin polyglutamylase complex subunit 2 -1.57324
ACADL acyl-CoA dehydrogenase, long chain -1.57216
WASF3 WAS protein family, member 3 -1.56921
NUP93 nucleoporin 93kDa -1.56864
MLH1 mutL homolog 1 -1.5639
NIPSNAP3B nipsnap homolog 3B (C. elegans) -1.55781
ITGB6 integrin, beta 6 -1.55751
TRA2B transformer 2 beta homolog (Drosophila) -1.55158
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -1.55023
RIC8B RIC8 guanine nucleotide exchange factor B -1.54721
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -1.5455
FAM111A family with sequence similarity 111, member A -1.54544
HEXB hexosaminidase B (beta polypeptide) -1.54445
RIPK2 receptor-interacting serine-threonine kinase 2 -1.54387
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -1.5435
ZMYM3 zinc finger, MYM-type 3 -1.54223
TACSTD2 tumor-associated calcium signal transducer 2 -1.53639
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -1.53527
BTN2A2 butyrophilin, subfamily 2, member A2 -1.53459
HDAC1 histone deacetylase 1 -1.53156
SAMM50 SAMM50 sorting and assembly machinery component -1.5288
GLT8D1 glycosyltransferase 8 domain containing 1 -1.52623
SEPT7 septin 7 -1.52592
PAX7 paired box 7 -1.52163
ALG6 ALG6, alpha-1,3-glucosyltransferase -1.52015
RPGR retinitis pigmentosa GTPase regulator -1.51785
IPO5 importin 5 -1.51355
TCP1 t-complex 1 -1.51254
B3GNT1 -1.51252
RPH3AL rabphilin 3A-like (without C2 domains) -1.51112
NPDC1 neural proliferation, differentiation and control, 1 -1.51018
TLN2 talin 2 -1.50855
EIF3D eukaryotic translation initiation factor 3, subunit D -1.50836
F3 coagulation factor III (thromboplastin, tissue factor) -1.5072
ARHGAP19 Rho GTPase activating protein 19 -1.50157
MGLL monoglyceride lipase -1.50151
CYTL1 cytokine-like 1 -1.50026
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -1.49599
IL20RB interleukin 20 receptor beta -1.4943
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -1.49206
FZD4 frizzled class receptor 4 -1.48927
COPB1 coatomer protein complex, subunit beta 1 -1.48678
FTCD formimidoyltransferase cyclodeaminase -1.48346
PERP PERP, TP53 apoptosis effector -1.48297
GPR89B G protein-coupled receptor 89B -1.48052
SNX24 sorting nexin 24 -1.47263
CLEC4A C-type lectin domain family 4, member A -1.4711
SH2D3A SH2 domain containing 3A -1.46611
FGR FGR proto-oncogene, Src family tyrosine kinase -1.46031
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 -1.45788
AMOTL2 angiomotin like 2 -1.45496
GTDC1 glycosyltransferase-like domain containing 1 -1.45496
WDR19 WD repeat domain 19 -1.45458
CHPT1 choline phosphotransferase 1 -1.45342
NLGN1 neuroligin 1 -1.45199
METTL9 methyltransferase like 9 -1.44989
PRCP prolylcarboxypeptidase (angiotensinase C) -1.44701
MPP1 membrane protein, palmitoylated 1, 55kDa -1.44297
DAPK1 death-associated protein kinase 1 -1.44274
ANXA2 annexin A2 -1.44027
AFTPH aftiphilin -1.43867
VIPR2 vasoactive intestinal peptide receptor 2 -1.43829
MPC1 mitochondrial pyruvate carrier 1 -1.43291
PEBP1 phosphatidylethanolamine binding protein 1 -1.43029
GSTM5 glutathione S-transferase mu 5 -1.43016
MYD88 myeloid differentiation primary response 88 -1.42896
LTA4H leukotriene A4 hydrolase -1.42739
RFC1 replication factor C (activator 1) 1, 145kDa -1.42739
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 -1.42508
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -1.42335
COMMD9 COMM domain containing 9 -1.42276
FBXL4 F-box and leucine-rich repeat protein 4 -1.42022
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 -1.41978
ELF2 E74-like factor 2 (ets domain transcription factor) -1.41314
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -1.41249
PEX19 peroxisomal biogenesis factor 19 -1.40871
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -1.40782
PDGFRL platelet-derived growth factor receptor-like -1.40768
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.40682
REM1 RAS (RAD and GEM)-like GTP-binding 1 -1.40455
WDR77 WD repeat domain 77 -1.40317
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 -1.40256
GUSB glucuronidase, beta -1.39948
DPP4 dipeptidyl-peptidase 4 -1.39837
CHMP2A charged multivesicular body protein 2A -1.3975
IMMT inner membrane protein, mitochondrial -1.39703
C1ORF95 chromosome 1 open reading frame 95 -1.39652
MBP myelin basic protein -1.39651
PARP2 poly (ADP-ribose) polymerase 2 -1.39552
PITPNA phosphatidylinositol transfer protein, alpha -1.39525
LAPTM4A lysosomal protein transmembrane 4 alpha -1.39367
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -1.38735
C1S complement component 1, s subcomponent -1.38521
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -1.3842
NR3C2 nuclear receptor subfamily 3, group C, member 2 -1.38354
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 -1.38038
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -1.37879
HDAC2 histone deacetylase 2 -1.37603
ABLIM1 actin binding LIM protein 1 -1.37398
C2ORF42 chromosome 2 open reading frame 42 -1.37197
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -1.37144
TXNDC15 thioredoxin domain containing 15 -1.37095
RXRG retinoid X receptor, gamma -1.36944
GOT1 glutamic-oxaloacetic transaminase 1, soluble -1.36633
GLO1 glyoxalase I -1.36624
BACE1 beta-site APP-cleaving enzyme 1 -1.36606
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -1.36403
OR7E14P olfactory receptor, family 7, subfamily E, member 14 pseudogene -1.36347
TPST2 tyrosylprotein sulfotransferase 2 -1.36119
GMDS GDP-mannose 4,6-dehydratase -1.35913
STK39 serine threonine kinase 39 -1.35864
ACVR1 activin A receptor, type I -1.35316
IL15 interleukin 15 -1.35258
NEK4 NIMA-related kinase 4 -1.35234
AIM1 absent in melanoma 1 -1.35201
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -1.35079
GCC2 GRIP and coiled-coil domain containing 2 -1.35071
FZD2 frizzled class receptor 2 -1.34989
TSC22D3 TSC22 domain family, member 3 -1.34978
CTCF CCCTC-binding factor (zinc finger protein) -1.34878
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -1.34763
PCCB propionyl CoA carboxylase, beta polypeptide -1.3466
LASP1 LIM and SH3 protein 1 -1.34597
GOLGB1 golgin B1 -1.34581
TMEM100 transmembrane protein 100 -1.3425
LPXN leupaxin -1.34199
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing -1.34174
NECAP1 NECAP endocytosis associated 1 -1.33894
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -1.33879
RBBP4 retinoblastoma binding protein 4 -1.33875
KDM4C lysine (K)-specific demethylase 4C -1.33661
SYNJ1 synaptojanin 1 -1.33546
SEC13 SEC13 homolog (S. cerevisiae) -1.33378
NT5C2 5'-nucleotidase, cytosolic II -1.33312
RPS28 ribosomal protein S28 -1.33243
FBXO7 F-box protein 7 -1.33016
HLTF helicase-like transcription factor -1.32973
CORT cortistatin -1.32845
ACSL5 acyl-CoA synthetase long-chain family member 5 -1.32646
TTC1 tetratricopeptide repeat domain 1 -1.3194
WNT2B wingless-type MMTV integration site family, member 2B -1.31832
AVPI1 arginine vasopressin-induced 1 -1.31804
GALC galactosylceramidase -1.31798
CMC2 C-x(9)-C motif containing 2 -1.31625
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 -1.31472
CHAF1A chromatin assembly factor 1, subunit A (p150) -1.31433