Urologic Neoplasms Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D014571
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Genes

218 genes/proteins associated with the disease Urologic Neoplasms from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CCND1 cyclin D1 2.88009
TP53 tumor protein p53 2.88009
WWOX WW domain containing oxidoreductase 2.88009
FHIT fragile histidine triad 2.88009
ATR ATR serine/threonine kinase 2.88009
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 2.88009
MGMT O-6-methylguanine-DNA methyltransferase 1.62646
GSTM1 glutathione S-transferase mu 1 1.55747
DDIT3 DNA-damage-inducible transcript 3 1.52161
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.46304
BIRC3 baculoviral IAP repeat containing 3 1.45564
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.44982
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.4479
NFE2L2 nuclear factor, erythroid 2-like 2 1.44409
MPG N-methylpurine-DNA glycosylase 1.44355
CYCS cytochrome c, somatic 1.43293
PCNA proliferating cell nuclear antigen 1.42804
HSPA1A heat shock 70kDa protein 1A 1.4026
SFRP2 secreted frizzled-related protein 2 1.3973
KEAP1 kelch-like ECH-associated protein 1 1.3827
PARP1 poly (ADP-ribose) polymerase 1 1.37846
XPA xeroderma pigmentosum, complementation group A 1.37446
BUB3 BUB3 mitotic checkpoint protein 1.35849
EPCAM epithelial cell adhesion molecule 1.3414
GADD45A growth arrest and DNA-damage-inducible, alpha 1.32577
MT1A metallothionein 1A 1.31686
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.31506
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.31327
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 1.3103
SRPK2 SRSF protein kinase 2 1.3039
MAPK1 mitogen-activated protein kinase 1 1.3039
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.30056
NQO1 NAD(P)H dehydrogenase, quinone 1 1.29657
TOP2A topoisomerase (DNA) II alpha 170kDa 1.28827
FUBP1 far upstream element (FUSE) binding protein 1 1.28703
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.28672
FAS Fas cell surface death receptor 1.2861
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.2861
HMOX1 heme oxygenase 1 1.28395
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 1.28241
XDH xanthine dehydrogenase 1.28058
HRAS Harvey rat sarcoma viral oncogene homolog 1.27626
MCL1 myeloid cell leukemia 1 1.27533
BAX BCL2-associated X protein 1.27224
NRG1 neuregulin 1 1.26947
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.26825
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.26514
E2F3 E2F transcription factor 3 1.26452
STK39 serine threonine kinase 39 1.26113
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.25929
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 1.25745
HSPB1 heat shock 27kDa protein 1 1.25713
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.25619
RFC5 replication factor C (activator 1) 5, 36.5kDa 1.254
PDPK1 3-phosphoinositide dependent protein kinase 1 1.24718
BID BH3 interacting domain death agonist 1.24655
GFRA1 GDNF family receptor alpha 1 1.24087
CDK2 cyclin-dependent kinase 2 1.23296
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.22853
MAPK14 mitogen-activated protein kinase 14 1.22821
CCNG1 cyclin G1 1.22566
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.22274
IER3 immediate early response 3 1.22112
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.2208
SRXN1 sulfiredoxin 1 1.21823
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 1.21631
RSAD2 radical S-adenosyl methionine domain containing 2 1.21337
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.21337
CDK1 cyclin-dependent kinase 1 1.21173
BCL2L1 BCL2-like 1 1.21108
GSTP1 glutathione S-transferase pi 1 1.20328
CRYAB crystallin, alpha B 1.2013
SGK1 serum/glucocorticoid regulated kinase 1 1.2013
F3 coagulation factor III (thromboplastin, tissue factor) 1.19868
TRIB3 tribbles pseudokinase 3 1.19477
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.18915
BIRC5 baculoviral IAP repeat containing 5 1.18882
TIMP2 TIMP metallopeptidase inhibitor 2 1.18126
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.17893
LBP lipopolysaccharide binding protein 1.17662
USP36 ubiquitin specific peptidase 36 1.17596
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 1.17168
COL18A1 collagen, type XVIII, alpha 1 1.17168
TPD52L2 tumor protein D52-like 2 1.17067
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.16866
PPARG peroxisome proliferator-activated receptor gamma 1.16302
TYMS thymidylate synthetase 1.16302
NME1 NME/NM23 nucleoside diphosphate kinase 1 1.16035
BCL6 B-cell CLL/lymphoma 6 1.16001
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.15865
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 1.15865
CAT catalase 1.1556
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.15357
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 1.15324
CAPN2 calpain 2, (m/II) large subunit 1.15324
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 1.14954
GCLC glutamate-cysteine ligase, catalytic subunit 1.14885
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.14816
BHMT betaine--homocysteine S-methyltransferase 1.14678
GSTT1 glutathione S-transferase theta 1 1.14575
CD2AP CD2-associated protein 1.14234
MAP2K1 mitogen-activated protein kinase kinase 1 1.14132
HSPA8 heat shock 70kDa protein 8 1.13793
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.13655
SALL1 spalt-like transcription factor 1 1.13313
VEGFA vascular endothelial growth factor A 1.13313
JUN jun proto-oncogene 1.13245
BAD BCL2-associated agonist of cell death 1.13041
KDM4B lysine (K)-specific demethylase 4B 1.12805
PLK1 polo-like kinase 1 1.12461
SOD2 superoxide dismutase 2, mitochondrial 1.12461
VIM vimentin 1.12426
GHR growth hormone receptor 1.12254
FASLG Fas ligand (TNF superfamily, member 6) 1.12219
DIABLO diablo, IAP-binding mitochondrial protein 1.12082
NEFL neurofilament, light polypeptide 1.12082
KIF3A kinesin family member 3A 1.11911
MSRA methionine sulfoxide reductase A 1.11877
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.11501
BECN1 beclin 1, autophagy related 1.11501
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.11466
ODC1 ornithine decarboxylase 1 1.11081
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.10942
EGFR epidermal growth factor receptor 1.10907
IFRD1 interferon-related developmental regulator 1 1.10803
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 1.10769
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 1.10596
NRP1 neuropilin 1 1.10596
TJP3 tight junction protein 3 1.10562
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.10246
PARD3 par-3 family cell polarity regulator 1.1014
POR P450 (cytochrome) oxidoreductase 1.09857
GSR glutathione reductase 1.09716
INHBA inhibin, beta A 1.09716
TDG thymine-DNA glycosylase 1.09401
CASP12 caspase 12 (gene/pseudogene) 1.0919
PDIA3 protein disulfide isomerase family A, member 3 1.0919
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.09083
OAT ornithine aminotransferase 1.09047
CTH cystathionine gamma-lyase 1.09011
MAPK9 mitogen-activated protein kinase 9 1.08904
ALAD aminolevulinate dehydratase 1.08868
EGF epidermal growth factor 1.08797
FOS FBJ murine osteosarcoma viral oncogene homolog 1.08161
CSE1L CSE1 chromosome segregation 1-like (yeast) 1.08161
GCLM glutamate-cysteine ligase, modifier subunit 1.08091
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.08091
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.08055
TXNRD1 thioredoxin reductase 1 1.07983
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) 1.07911
PDCD5 programmed cell death 5 1.07804
CREG1 cellular repressor of E1A-stimulated genes 1 1.07553
SET SET nuclear proto-oncogene 1.07447
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 1.07447
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.07411
HSPA9 heat shock 70kDa protein 9 (mortalin) 1.07234
CACYBP calcyclin binding protein 1.07199
ZNF552 zinc finger protein 552 1.07022
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.06987
MAPK3 mitogen-activated protein kinase 3 1.06917
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.06844
RUNX3 runt-related transcription factor 3 1.06771
EIF3A eukaryotic translation initiation factor 3, subunit A 1.06771
SOD1 superoxide dismutase 1, soluble 1.06771
CDC25C cell division cycle 25C 1.06625
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.06625
RAD51 RAD51 recombinase 1.06479
COL6A2 collagen, type VI, alpha 2 1.06406
RAP1A RAP1A, member of RAS oncogene family 1.0637
CDC20 cell division cycle 20 1.06152
APAF1 apoptotic peptidase activating factor 1 1.06152
ERBB4 erb-b2 receptor tyrosine kinase 4 1.06116
PTK2 protein tyrosine kinase 2 1.06008
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 1.05864
GPX1 glutathione peroxidase 1 1.05828
LSG1 large 60S subunit nuclear export GTPase 1 1.05757
ANXA5 annexin A5 1.05573
APOB apolipoprotein B 1.05423
BIRC2 baculoviral IAP repeat containing 2 1.05126
TRIM2 tripartite motif containing 2 1.05052
RBPMS RNA binding protein with multiple splicing 1.05052
MAP3K6 mitogen-activated protein kinase kinase kinase 6 1.05015
IL1RAP interleukin 1 receptor accessory protein 1.05015
CFLAR CASP8 and FADD-like apoptosis regulator 1.04831
POM121 POM121 transmembrane nucleoporin 1.04611
GSK3B glycogen synthase kinase 3 beta 1.04611
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.04538
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.04465
CCNB2 cyclin B2 1.04389
ANXA1 annexin A1 1.04389
ERCC5 excision repair cross-complementation group 5 1.04088
GPX3 glutathione peroxidase 3 1.03864
RRM2B ribonucleotide reductase M2 B (TP53 inducible) 1.03827
IL1RN interleukin 1 receptor antagonist 1.03827
UMPS uridine monophosphate synthetase 1.03789
IHH indian hedgehog 1.03789
HSPA1B heat shock 70kDa protein 1B 1.03715
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 1.03604
BAK1 BCL2-antagonist/killer 1 1.03567
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.03456
CALD1 caldesmon 1 1.03456
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 1.03456
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.03419
MELK maternal embryonic leucine zipper kinase 1.03235
TRAF2 TNF receptor-associated factor 2 1.02933
BTG3 BTG family, member 3 1.02933
FDXR ferredoxin reductase 1.02896
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 1.02746
CXCR4 chemokine (C-X-C motif) receptor 4 1.02634
CCND2 cyclin D2 1.02485
FKBP1A FK506 binding protein 1A, 12kDa 1.02373
POLB polymerase (DNA directed), beta 1.0204
CES3 carboxylesterase 3 1.01852
TSC2 tuberous sclerosis 2 1.01587
CCNB1 cyclin B1 1.01474
PSAP prosaposin 1.01249
CD44 CD44 molecule (Indian blood group) 1.01212
VCAM1 vascular cell adhesion molecule 1 1.01174