Ulcer Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D014456
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Genes

214 genes/proteins associated with the disease Ulcer from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
DDIT3 DNA-damage-inducible transcript 3 2.88009
PPIF peptidylprolyl isomerase F 2.88009
MPO myeloperoxidase 2.17469
IL1B interleukin 1, beta 2.08116
IL6 interleukin 6 2.00357
TNF tumor necrosis factor 1.953
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.93953
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.90721
IFNG interferon, gamma 1.89796
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.87875
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.81092
BAX BCL2-associated X protein 1.80322
CXCL8 chemokine (C-X-C motif) ligand 8 1.79904
ICAM1 intercellular adhesion molecule 1 1.79904
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.75261
NOS2 nitric oxide synthase 2, inducible 1.73332
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.72821
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.72613
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.70988
ALB albumin 1.6906
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.68761
MAPK3 mitogen-activated protein kinase 3 1.63698
FASLG Fas ligand (TNF superfamily, member 6) 1.63361
IL4 interleukin 4 1.61575
HSPA1A heat shock 70kDa protein 1A 1.60921
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.60851
BCL2 B-cell CLL/lymphoma 2 1.60641
HMOX1 heme oxygenase 1 1.59474
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.59172
CAT catalase 1.5903
FOS FBJ murine osteosarcoma viral oncogene homolog 1.58065
GAST gastrin 1.56632
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.55995
IL10 interleukin 10 1.55822
CCND1 cyclin D1 1.55378
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.54548
MMP9 matrix metallopeptidase 9 1.52061
IL12A interleukin 12A 1.50979
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.50624
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.50198
CCL2 chemokine (C-C motif) ligand 2 1.4871
PCNA proliferating cell nuclear antigen 1.47762
MAPK1 mitogen-activated protein kinase 1 1.47064
FAS Fas cell surface death receptor 1.46727
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.46093
PARP1 poly (ADP-ribose) polymerase 1 1.45405
CALCA calcitonin-related polypeptide alpha 1.45089
CTGF connective tissue growth factor 1.437
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.43646
GSK3B glycogen synthase kinase 3 beta 1.43455
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.42129
CFLAR CASP8 and FADD-like apoptosis regulator 1.42129
DUSP1 dual specificity phosphatase 1 1.40345
VCAM1 vascular cell adhesion molecule 1 1.39114
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.3903
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.37817
CCL3 chemokine (C-C motif) ligand 3 1.37446
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.37446
JUN jun proto-oncogene 1.37418
PRL prolactin 1.37217
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.36876
EGR1 early growth response 1 1.36361
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.36275
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.35991
IL1A interleukin 1, alpha 1.35849
IL2 interleukin 2 1.35502
FDFT1 farnesyl-diphosphate farnesyltransferase 1 1.34053
LDLR low density lipoprotein receptor 1.33523
GSTT1 glutathione S-transferase theta 1 1.32816
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.32726
EGFR epidermal growth factor receptor 1.31927
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.31837
PPARG peroxisome proliferator-activated receptor gamma 1.31297
IL18 interleukin 18 1.31059
APAF1 apoptotic peptidase activating factor 1 1.30881
TGFB1 transforming growth factor, beta 1 1.30666
SELL selectin L 1.30451
NPPA natriuretic peptide A 1.30117
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.28425
COL1A1 collagen, type I, alpha 1 1.28058
VEGFA vascular endothelial growth factor A 1.2744
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.27347
BCL2L1 BCL2-like 1 1.26763
SNCA synuclein, alpha (non A4 component of amyloid precursor) 1.26763
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.26113
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 1.25245
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.25121
NR1I3 nuclear receptor subfamily 1, group I, member 3 1.24905
UGT1A3 UDP glucuronosyltransferase 1 family, polypeptide A3 1.24433
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.24118
S100A4 S100 calcium binding protein A4 1.23962
IL12B interleukin 12B 1.23899
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 1.23584
REN renin 1.2208
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.21599
IGFBP3 insulin-like growth factor binding protein 3 1.2137
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 1.20913
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.20654
CTH cystathionine gamma-lyase 1.20427
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.20229
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.20229
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.20196
NGF nerve growth factor (beta polypeptide) 1.19379
HSPA8 heat shock 70kDa protein 8 1.18981
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 1.18948
IL5 interleukin 5 1.18193
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.17926
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.17926
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.17464
CLU clusterin 1.17268
XDH xanthine dehydrogenase 1.17268
FGF21 fibroblast growth factor 21 1.17067
PTK2 protein tyrosine kinase 2 1.167
MCL1 myeloid cell leukemia 1 1.16633
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.16533
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.15763
MAP2K2 mitogen-activated protein kinase kinase 2 1.15627
RB1 retinoblastoma 1 1.1556
CYCS cytochrome c, somatic 1.14747
TH tyrosine hydroxylase 1.14678
GSTP1 glutathione S-transferase pi 1 1.14678
TAC1 tachykinin, precursor 1 1.14575
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.142
PPP1R15A protein phosphatase 1, regulatory subunit 15A 1.142
CXCL10 chemokine (C-X-C motif) ligand 10 1.13963
GCLC glutamate-cysteine ligase, catalytic subunit 1.13862
BAK1 BCL2-antagonist/killer 1 1.13724
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.13518
PECAM1 platelet/endothelial cell adhesion molecule 1 1.13381
BID BH3 interacting domain death agonist 1.13143
NTF3 neurotrophin 3 1.13109
CRYAB crystallin, alpha B 1.12872
CAPN2 calpain 2, (m/II) large subunit 1.12838
EGF epidermal growth factor 1.12838
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.12599
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 1.12564
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 1.12288
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 1.11945
LCN2 lipocalin 2 1.11911
EDN1 endothelin 1 1.11843
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.11707
SAT1 spermidine/spermine N1-acetyltransferase 1 1.11571
CSF1 colony stimulating factor 1 (macrophage) 1.11081
MAPK14 mitogen-activated protein kinase 14 1.10942
CD44 CD44 molecule (Indian blood group) 1.10803
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 1.10493
TIMP2 TIMP metallopeptidase inhibitor 2 1.10493
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.10104
FOSL1 FOS-like antigen 1 1.10033
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.09611
HSDL2 hydroxysteroid dehydrogenase like 2 1.09611
HSF1 heat shock transcription factor 1 1.0919
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.09154
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.09154
NOS3 nitric oxide synthase 3 (endothelial cell) 1.08904
MMP2 matrix metallopeptidase 2 1.08762
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 1.08478
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 1.08372
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 1.08372
BTG1 B-cell translocation gene 1, anti-proliferative 1.08266
BHLHE40 basic helix-loop-helix family, member e40 1.08266
FOXO1 forkhead box O1 1.08055
NR1H3 nuclear receptor subfamily 1, group H, member 3 1.07411
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.07411
TIMP1 TIMP metallopeptidase inhibitor 1 1.06771
GGT1 gamma-glutamyltransferase 1 1.06734
ISYNA1 inositol-3-phosphate synthase 1 1.06442
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.06225
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 1.06152
PHYH phytanoyl-CoA 2-hydroxylase 1.0608
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.059
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 1.05685
ASIC3 acid sensing (proton gated) ion channel 3 1.05535
MKI67 marker of proliferation Ki-67 1.05535
NR4A2 nuclear receptor subfamily 4, group A, member 2 1.05498
HRH2 histamine receptor H2 1.05498
GADD45A growth arrest and DNA-damage-inducible, alpha 1.05312
IER5 immediate early response 5 1.05312
MMP1 matrix metallopeptidase 1 1.05126
ADRA1D adrenoceptor alpha 1D 1.05052
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.05015
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.04904
JUNB jun B proto-oncogene 1.04868
CD36 CD36 molecule (thrombospondin receptor) 1.04721
IL1R1 interleukin 1 receptor, type I 1.04684
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.04684
PRDX2 peroxiredoxin 2 1.04465
TOB1 transducer of ERBB2, 1 1.04276
TJP1 tight junction protein 1 1.04276
APOE apolipoprotein E 1.04088
STAT1 signal transducer and activator of transcription 1, 91kDa 1.03827
SYT7 synaptotagmin VII 1.03789
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.03715
PPARD peroxisome proliferator-activated receptor delta 1.03715
CES2 carboxylesterase 2 1.03678
SOD1 superoxide dismutase 1, soluble 1.03678
TP53 tumor protein p53 1.03493
FGF2 fibroblast growth factor 2 (basic) 1.03456
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.03308
CSNK2A1 casein kinase 2, alpha 1 polypeptide 1.02596
RGS2 regulator of G-protein signaling 2 1.02559
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.02522
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.02485
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.02447
DUSP10 dual specificity phosphatase 10 1.02262
PKM pyruvate kinase, muscle 1.02188
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 1.01966
CYBA cytochrome b-245, alpha polypeptide 1.01437
CYBB cytochrome b-245, beta polypeptide 1.01286
CDK4 cyclin-dependent kinase 4 1.01137
CHUK conserved helix-loop-helix ubiquitous kinase 1.01137
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial 1.01062
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.01025
BCAT1 branched chain amino-acid transaminase 1, cytosolic 1.01025