UQCRB Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ubiquinol-cytochrome c reductase binding protein|This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X. [provided by RefSeq, Dec 2011] (NCBI Entrez Gene Database, 7381)
External Link http://www.ncbi.nlm.nih.gov/gene/7381
Similar Terms
Downloads & Tools

Genes

31 interacting proteins for UQCRB from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACAT1 acetyl-CoA acetyltransferase 1
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
CEP76 centrosomal protein 76kDa
COX5A cytochrome c oxidase subunit Va
CYCS cytochrome c, somatic
MAGEA1 melanoma antigen family A1
MAGEA4 melanoma antigen family A4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
NRF1 nuclear respiratory factor 1
RPL11 ribosomal protein L11
RPL14 ribosomal protein L14
RPL23 ribosomal protein L23
RPL6 ribosomal protein L6
RPS10 ribosomal protein S10
RPS16 ribosomal protein S16
RPS2 ribosomal protein S2
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
UBC ubiquitin C
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X
UQCRC1 ubiquinol-cytochrome c reductase core protein I
UQCRC2 ubiquinol-cytochrome c reductase core protein II
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa