Type 2 diabetes Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description disease cluster belonging to disease group metabolic (Genetic Association Database)
External Link https://www.ebi.ac.uk/gwas/search?query=Type 2 diabetes
Similar Terms
Downloads & Tools

Genes

74 genes associated with the Type 2 diabetes phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.74874
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.45497
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.20529
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 1.122
FTO fat mass and obesity associated 1.06007
MAEA macrophage erythroblast attacher 1.04952
LOC646736 uncharacterized LOC646736 1.03493
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 1.01293
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.976249
SLC16A11 solute carrier family 16, member 11 0.831366
GLIS3 GLIS family zinc finger 3 0.802698
JAZF1 JAZF zinc finger 1 0.781677
LOC101928423 uncharacterized LOC101928423 0.740948
SLC16A13 solute carrier family 16, member 13 0.718348
ZBED3-AS1 ZBED3 antisense RNA 1 0.686534
HMG20A high mobility group 20A 0.637972
HNF1B HNF1 homeobox B 0.637972
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.626595
ZMIZ1 zinc finger, MIZ-type containing 1 0.572839
ZFAND3 zinc finger, AN1-type domain 3 0.572839
GPSM1 G-protein signaling modulator 1 0.572839
HNF4A hepatocyte nuclear factor 4, alpha 0.560615
PPARG peroxisome proliferator-activated receptor gamma 0.539238
PTPRD protein tyrosine phosphatase, receptor type, D 0.526478
THADA thyroid adenoma associated 0.522843
WFS1 Wolfram syndrome 1 (wolframin) 0.499091
FAM58A family with sequence similarity 58, member A 0.499091
SRR serine racemase 0.483518
POU5F1 POU class 5 homeobox 1 0.472799
RPSAP52 ribosomal protein SA pseudogene 52 0.472799
FAF1 Fas (TNFRSF6) associated factor 1 0.472799
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.472799
GRK5 G protein-coupled receptor kinase 5 0.449549
ARL15 ADP-ribosylation factor-like 15 0.449549
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.449549
LAMA1 laminin, alpha 1 0.444144
MPHOSPH9 M-phase phosphoprotein 9 0.434785
ADAMTS9-AS2 ADAMTS9 antisense RNA 2 0.434785
PEPD peptidase D 0.434785
OASL 2'-5'-oligoadenylate synthetase-like 0.405958
ADCY5 adenylate cyclase 5 0.405958
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.405958
SDHAF4 succinate dehydrogenase complex assembly factor 4 0.389385
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.389385
RBMS1 RNA binding motif, single stranded interacting protein 1 0.377988
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.377988
NOTCH2 notch 2 0.377988
DNER delta/notch-like EGF repeat containing 0.356403
MTNR1B melatonin receptor 1B 0.314454
RNF6 ring finger protein (C3H2C3 type) 6 0.314454
CMIP c-Maf inducing protein 0.295129
DGKB diacylglycerol kinase, beta 90kDa 0.295129
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.255654
CDKN2B-AS1 CDKN2B antisense RNA 1 0.220915
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.220915
RHOU ras homolog family member U 0.165905
PCBD2 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 0.165905
PROX1-AS1 PROX1 antisense RNA 1 0.165905
LOC101927502 uncharacterized LOC101927502 0.165905
DCDC2C doublecortin domain containing 2C 0.129504
PALM2 paralemmin 2 0.129504
TGFBR3 transforming growth factor, beta receptor III 0.104568
HNF1A HNF1 homeobox A 0.104568
SYK spleen tyrosine kinase 0.085234
TCERG1L transcription elongation regulator 1-like 0.085234
ACHE acetylcholinesterase (Yt blood group) 0.085234
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.057619
PEX5L peroxisomal biogenesis factor 5-like 0.057619
HIGD1C HIG1 hypoxia inducible domain family, member 1C 0.057619
CRHR2 corticotropin releasing hormone receptor 2 0.048624
LINGO2 leucine rich repeat and Ig domain containing 2 0.048624
PLS1 plastin 1 0.042592
PAPL iron/zinc purple acid phosphatase-like protein 0.042592
MARCH1 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase 0.042592