Type 2 diabetes nephropathy Gene Set

Dataset GWAS Catalog SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Diabetic nephropathy is a progressive kidney disease caused by angiopathy of capillaries in the kidney glomeruli. In type 2 diabetes hyperglycaemia starts after the forties, usually when the kidneys have already suffered the longā€term consequences of ageing and of other recognized promoters of chronic renal injury such as arterial hypertension, obesity, dyslipidaemia, and smoking. (Experimental Factor Ontology, EFO_0004997)
External Link https://www.ebi.ac.uk/gwas/search?query=Type 2 diabetes nephropathy
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Genes

3 genes associated with the Type 2 diabetes nephropathy phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SASH1 SAM and SH3 domain containing 1 0.246511
LIMK2 LIM domain kinase 2 0.104568
ELMO1 engulfment and cell motility 1 0.048624