Type 2 diabetes mellitus_Renal Tissue_GSE642 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE642
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Genes

600 genes differentially expressed during Type 2 diabetes mellitus_Renal Tissue_GSE642 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
UBL3 ubiquitin-like 3 3.51818
RPIA ribose 5-phosphate isomerase A 3.47524
MAN2C1 mannosidase, alpha, class 2C, member 1 3.27017
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 3.23588
CAPN6 calpain 6 2.96257
TAPBP TAP binding protein (tapasin) 2.91725
PGRMC1 progesterone receptor membrane component 1 2.89743
FICD FIC domain containing 2.89128
UBE2K ubiquitin-conjugating enzyme E2K 2.7567
TMC6 transmembrane channel-like 6 2.70849
CAT catalase 2.67894
LRWD1 leucine-rich repeats and WD repeat domain containing 1 2.67814
CHCHD5 coiled-coil-helix-coiled-coil-helix domain containing 5 2.63048
TOP2B topoisomerase (DNA) II beta 180kDa 2.62127
SLC16A6 solute carrier family 16, member 6 2.59756
PPP5C protein phosphatase 5, catalytic subunit 2.59586
FTO fat mass and obesity associated 2.59051
CIRBP cold inducible RNA binding protein 2.57374
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 2.56485
STXBP3 syntaxin binding protein 3 2.5621
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.55005
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 2.50845
ZNF148 zinc finger protein 148 2.50423
GPX1 glutathione peroxidase 1 2.50389
SARS2 seryl-tRNA synthetase 2, mitochondrial 2.49258
TMED7 transmembrane emp24 protein transport domain containing 7 2.48675
S1PR3 sphingosine-1-phosphate receptor 3 2.44646
HPCAL4 hippocalcin like 4 2.43407
STX12 syntaxin 12 2.36268
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 2.34317
HBE1 hemoglobin, epsilon 1 2.31226
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 2.31222
SSTR4 somatostatin receptor 4 2.30729
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 2.30539
ACTB actin, beta 2.30342
CYC1 cytochrome c-1 2.29959
DNM1L dynamin 1-like 2.28567
MPDU1 mannose-P-dolichol utilization defect 1 2.25234
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.22534
FAM53A family with sequence similarity 53, member A 2.21819
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1 2.21016
SBF2 SET binding factor 2 2.2097
CTSF cathepsin F 2.20885
PBX2 pre-B-cell leukemia homeobox 2 2.1849
OXT oxytocin/neurophysin I prepropeptide 2.1816
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 2.15259
C20ORF24 chromosome 20 open reading frame 24 2.14449
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 2.1388
RCN2 reticulocalbin 2, EF-hand calcium binding domain 2.12911
RPL37A ribosomal protein L37a 2.12837
SRCAP Snf2-related CREBBP activator protein 2.1256
SSBP2 single-stranded DNA binding protein 2 2.12074
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 2.11489
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.10885
FAM173A family with sequence similarity 173, member A 2.10759
TBRG1 transforming growth factor beta regulator 1 2.09077
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 2.08079
RNASEH2C ribonuclease H2, subunit C 2.06939
GOSR1 golgi SNAP receptor complex member 1 2.06545
ANXA4 annexin A4 2.06231
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 2.05205
ZNF131 zinc finger protein 131 2.02663
ANXA6 annexin A6 2.0231
FKBP1A FK506 binding protein 1A, 12kDa 2.02241
RHOA ras homolog family member A 2.01927
NUDCD3 NudC domain containing 3 2.01824
KRT86 keratin 86, type II 2.01605
SPAG7 sperm associated antigen 7 2.01212
CSNK2B casein kinase 2, beta polypeptide 2.00706
ZNHIT1 zinc finger, HIT-type containing 1 2.00427
GSTA5 glutathione S-transferase alpha 5 2.00026
PLK2 polo-like kinase 2 1.99698
PPP1R18 protein phosphatase 1, regulatory subunit 18 1.98882
SEC11C SEC11 homolog C (S. cerevisiae) 1.98006
RAB31 RAB31, member RAS oncogene family 1.9742
PEX11B peroxisomal biogenesis factor 11 beta 1.97284
GPC3 glypican 3 1.96544
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 1.96078
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 1.95169
EXOSC4 exosome component 4 1.95044
CLU clusterin 1.94984
TMEM159 transmembrane protein 159 1.94947
DAPK2 death-associated protein kinase 2 1.94668
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 1.92493
MYPOP Myb-related transcription factor, partner of profilin 1.9213
EFNA3 ephrin-A3 1.92013
MRPL3 mitochondrial ribosomal protein L3 1.91874
INPP5K inositol polyphosphate-5-phosphatase K 1.91794
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 1.91538
SEC31A SEC31 homolog A (S. cerevisiae) 1.91022
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 1.90888
DLD dihydrolipoamide dehydrogenase 1.90494
EFTUD1 elongation factor Tu GTP binding domain containing 1 1.88518
FAM63A family with sequence similarity 63, member A 1.88514
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.87867
GLO1 glyoxalase I 1.87625
H2AFY H2A histone family, member Y 1.86538
CKAP5 cytoskeleton associated protein 5 1.85604
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 1.85498
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 1.85376
DACH2 dachshund family transcription factor 2 1.85373
ADGRL1 adhesion G protein-coupled receptor L1 1.84949
S1PR2 sphingosine-1-phosphate receptor 2 1.84643
RTN4 reticulon 4 1.84048
MATR3 matrin 3 1.83876
UGP2 UDP-glucose pyrophosphorylase 2 1.83712
FAM50B family with sequence similarity 50, member B 1.82439
AUH AU RNA binding protein/enoyl-CoA hydratase 1.82187
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) 1.8136
USP22 ubiquitin specific peptidase 22 1.81281
SF3B3 splicing factor 3b, subunit 3, 130kDa 1.81242
SNIP1 Smad nuclear interacting protein 1 1.80865
SFRP2 secreted frizzled-related protein 2 1.8068
PPIC peptidylprolyl isomerase C (cyclophilin C) 1.80658
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36 1.79171
GPI glucose-6-phosphate isomerase 1.79091
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 1.77166
KIF5B kinesin family member 5B 1.77149
C16ORF74 chromosome 16 open reading frame 74 1.7593
CCNG1 cyclin G1 1.75797
LAMP2 lysosomal-associated membrane protein 2 1.75658
MTA2 metastasis associated 1 family, member 2 1.74769
F2R coagulation factor II (thrombin) receptor 1.74534
FSIP1 fibrous sheath interacting protein 1 1.74165
ATXN7L3 ataxin 7-like 3 1.73755
WDR7 WD repeat domain 7 1.73586
PDCD2L programmed cell death 2-like 1.73146
NPTX2 neuronal pentraxin II 1.73143
LIN9 lin-9 DREAM MuvB core complex component 1.72942
NFE2L1 nuclear factor, erythroid 2-like 1 1.72786
CTBP2 C-terminal binding protein 2 1.72427
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A 1.72221
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 1.72138
ACY1 aminoacylase 1 1.71991
ITM2B integral membrane protein 2B 1.71706
SPG21 spastic paraplegia 21 (autosomal recessive, Mast syndrome) 1.71554
STX6 syntaxin 6 1.70686
CPLX2 complexin 2 1.70576
RPL24 ribosomal protein L24 1.69761
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.69544
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 1.68492
CENPI centromere protein I 1.68059
IST1 increased sodium tolerance 1 homolog (yeast) 1.67905
TRIM11 tripartite motif containing 11 1.67734
POLM polymerase (DNA directed), mu 1.675
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 1.67288
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 1.66959
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.65799
CINP cyclin-dependent kinase 2 interacting protein 1.6574
YIPF1 Yip1 domain family, member 1 1.6566
CYB561 cytochrome b561 1.65402
ZNF771 zinc finger protein 771 1.65312
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 1.65255
TLE4 transducin-like enhancer of split 4 1.65142
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 1.64853
KLK3 kallikrein-related peptidase 3 1.64476
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9 1.64303
H1F0 H1 histone family, member 0 1.64169
VPREB1 pre-B lymphocyte 1 1.63483
YY1 YY1 transcription factor 1.63423
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 1.63245
UNC119 unc-119 homolog (C. elegans) 1.62894
ACTG2 actin, gamma 2, smooth muscle, enteric 1.62722
CLTB clathrin, light chain B 1.62279
EML5 echinoderm microtubule associated protein like 5 1.61919
RRP1B ribosomal RNA processing 1B 1.61709
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 1.61338
PTGES prostaglandin E synthase 1.61273
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 1.60892
OCIAD1 OCIA domain containing 1 1.60793
MCL1 myeloid cell leukemia 1 1.60742
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9 1.6025
SPTSSA serine palmitoyltransferase, small subunit A 1.60085
EMP3 epithelial membrane protein 3 1.59969
HNRNPL heterogeneous nuclear ribonucleoprotein L 1.58654
FOXO4 forkhead box O4 1.58624
LTA lymphotoxin alpha 1.58563
EIF3M eukaryotic translation initiation factor 3, subunit M 1.58139
ALLC allantoicase 1.57609
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 1.57606
ROGDI rogdi homolog (Drosophila) 1.57593
PRRC1 proline-rich coiled-coil 1 1.57483
SART1 squamous cell carcinoma antigen recognized by T cells 1.57377
RBPJ recombination signal binding protein for immunoglobulin kappa J region 1.56941
ACP1 acid phosphatase 1, soluble 1.56784
PCBP4 poly(rC) binding protein 4 1.56244
KCNK7 potassium channel, two pore domain subfamily K, member 7 1.55726
INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 1.55366
ALK anaplastic lymphoma receptor tyrosine kinase 1.54968
ACTL7B actin-like 7B 1.54749
CNN3 calponin 3, acidic 1.54674
PUS1 pseudouridylate synthase 1 1.5463
PLA2G1B phospholipase A2, group IB (pancreas) 1.54439
LGALS2 lectin, galactoside-binding, soluble, 2 1.5409
GCGR glucagon receptor 1.53652
ALDH1L2 aldehyde dehydrogenase 1 family, member L2 1.53349
STK24 serine/threonine kinase 24 1.53273
ELAC2 elaC ribonuclease Z 2 1.53263
RCAN1 regulator of calcineurin 1 1.53234
KIF16B kinesin family member 16B 1.53208
HDAC7 histone deacetylase 7 1.53109
ERCC2 excision repair cross-complementation group 2 1.53084
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.52028
NCOA2 nuclear receptor coactivator 2 1.51439
NFYB nuclear transcription factor Y, beta 1.51194
NCOA1 nuclear receptor coactivator 1 1.5104
TM9SF2 transmembrane 9 superfamily member 2 1.50279
PAIP2 poly(A) binding protein interacting protein 2 1.49496
MZT2A mitotic spindle organizing protein 2A 1.49387
FKBP3 FK506 binding protein 3, 25kDa 1.49114
CCBL2 cysteine conjugate-beta lyase 2 1.48767
SWI5 SWI5 recombination repair homolog (yeast) 1.48591
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 1.48423
GLUL glutamate-ammonia ligase 1.48385
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 1.48377
MFGE8 milk fat globule-EGF factor 8 protein 1.4793
FBP1 fructose-1,6-bisphosphatase 1 1.47483
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 1.47444
EPHA8 EPH receptor A8 1.47185
OR13J1 olfactory receptor, family 13, subfamily J, member 1 1.46865
FAM83G family with sequence similarity 83, member G 1.46835
WNT10A wingless-type MMTV integration site family, member 10A 1.46766
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 1.46528
CIC capicua transcriptional repressor 1.46367
CSRP1 cysteine and glycine-rich protein 1 1.46295
TUFM Tu translation elongation factor, mitochondrial 1.4615
CDK18 cyclin-dependent kinase 18 1.45375
AAK1 AP2 associated kinase 1 1.45374
ZDHHC5 zinc finger, DHHC-type containing 5 1.45365
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 1.45342
ESD esterase D 1.4523
COL9A2 collagen, type IX, alpha 2 1.45123
IGSF8 immunoglobulin superfamily, member 8 1.44905
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.44818
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 1.44765
LAPTM4A lysosomal protein transmembrane 4 alpha 1.44684
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.4429
DHODH dihydroorotate dehydrogenase (quinone) 1.44229
TFF1 trefoil factor 1 1.4359
STMN2 stathmin 2 1.43568
GTPBP1 GTP binding protein 1 1.43153
ARL2BP ADP-ribosylation factor-like 2 binding protein 1.4297
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.42552
MCM3 minichromosome maintenance complex component 3 1.42449
EPAS1 endothelial PAS domain protein 1 1.42363
ARL2 ADP-ribosylation factor-like 2 1.42114
PLK1 polo-like kinase 1 1.41628
CTNNBIP1 catenin, beta interacting protein 1 1.41516
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.40731
RRAGD Ras-related GTP binding D 1.40633
OSBPL1A oxysterol binding protein-like 1A 1.40322
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.40178
CLCNKB chloride channel, voltage-sensitive Kb 1.40142
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 1.39462
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI 1.39372
LAMC2 laminin, gamma 2 1.39142
PCOLCE procollagen C-endopeptidase enhancer 1.39106
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 1.38725
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 1.38653
WDR5 WD repeat domain 5 1.38484
DTX2 deltex 2, E3 ubiquitin ligase 1.38058
FAM84A family with sequence similarity 84, member A 1.37833
GSTO1 glutathione S-transferase omega 1 1.37366
HR hair growth associated 1.37058
ARHGAP12 Rho GTPase activating protein 12 1.36382
SLC25A44 solute carrier family 25, member 44 1.36173
NDUFA10 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa 1.3598
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 1.35929
SARDH sarcosine dehydrogenase 1.3554
ZNF362 zinc finger protein 362 1.35298
FGF4 fibroblast growth factor 4 1.35264
PYCR2 pyrroline-5-carboxylate reductase family, member 2 1.35253
FKBP2 FK506 binding protein 2, 13kDa 1.35061
KRT4 keratin 4, type II 1.35042
RASAL1 RAS protein activator like 1 (GAP1 like) 1.34945
MNAT1 MNAT CDK-activating kinase assembly factor 1 1.34903
SNTA1 syntrophin, alpha 1 1.34527
QRICH1 glutamine-rich 1 1.34459
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 1.34269
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1.34118
GJB1 gap junction protein, beta 1, 32kDa 1.33971
MTCH1 mitochondrial carrier 1 1.33469
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 1.33218
TUBA8 tubulin, alpha 8 1.32946
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.32893
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.32839
GDF3 growth differentiation factor 3 1.32787
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 1.32739
FAM46A family with sequence similarity 46, member A 1.32615
SPRED2 sprouty-related, EVH1 domain containing 2 1.32423
MORF4L1 mortality factor 4 like 1 1.32256
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 1.32181
MRPL43 mitochondrial ribosomal protein L43 1.32154
CTNND1 catenin (cadherin-associated protein), delta 1 1.32025
MYOD1 myogenic differentiation 1 1.32001
TCOF1 Treacher Collins-Franceschetti syndrome 1 1.31967
CSNK1A1 casein kinase 1, alpha 1 1.31911
ELOVL1 ELOVL fatty acid elongase 1 1.318
FAM3C family with sequence similarity 3, member C 1.31464
CD44 CD44 molecule (Indian blood group) 1.31357

decreased expression

Symbol Name Standardized Value
TXN thioredoxin -4.14749
HMGN1 high mobility group nucleosome binding domain 1 -3.84256
PTOV1 prostate tumor overexpressed 1 -3.43232
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -3.32022
NFS1 NFS1 cysteine desulfurase -3.2681
TMEM176A transmembrane protein 176A -3.24537
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -3.21059
CLPTM1 cleft lip and palate associated transmembrane protein 1 -3.20343
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide -3.11592
PABPC1 poly(A) binding protein, cytoplasmic 1 -3.08113
RPS27A ribosomal protein S27a -3.05111
COPS8 COP9 signalosome subunit 8 -3.0354
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -2.98865
SOD3 superoxide dismutase 3, extracellular -2.96284
GBA glucosidase, beta, acid -2.93148
IMP3 IMP3, U3 small nucleolar ribonucleoprotein -2.92126
HDAC1 histone deacetylase 1 -2.86515
NEURL4 neuralized E3 ubiquitin protein ligase 4 -2.85204
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -2.83743
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 -2.82875
COPS3 COP9 signalosome subunit 3 -2.80185
CECR6 cat eye syndrome chromosome region, candidate 6 -2.8005
LARP1 La ribonucleoprotein domain family, member 1 -2.8005
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.79844
EIF3G eukaryotic translation initiation factor 3, subunit G -2.76638
NAPSA napsin A aspartic peptidase -2.765
MPP1 membrane protein, palmitoylated 1, 55kDa -2.7519
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -2.73821
CTSA cathepsin A -2.7372
PERP PERP, TP53 apoptosis effector -2.66186
TBCB tubulin folding cofactor B -2.63798
HIGD2A HIG1 hypoxia inducible domain family, member 2A -2.62818
TESK1 testis-specific kinase 1 -2.6281
NIT1 nitrilase 1 -2.61417
SEPT7 septin 7 -2.60954
MRPS33 mitochondrial ribosomal protein S33 -2.60531
EIF4A3 eukaryotic translation initiation factor 4A3 -2.59702
EIF1B eukaryotic translation initiation factor 1B -2.59522
HIST1H3C histone cluster 1, H3c -2.57833
LRP2 low density lipoprotein receptor-related protein 2 -2.56833
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit -2.55381
AUP1 ancient ubiquitous protein 1 -2.53396
RPL10 ribosomal protein L10 -2.53137
PHF23 PHD finger protein 23 -2.51354
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.51008
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.50347
SAP30L SAP30-like -2.50014
UBL5 ubiquitin-like 5 -2.48991
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) -2.4717
SCAMP3 secretory carrier membrane protein 3 -2.46221
LARP4B La ribonucleoprotein domain family, member 4B -2.45863
CSNK1G2 casein kinase 1, gamma 2 -2.45833
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -2.43059
RAN RAN, member RAS oncogene family -2.42124
USP8 ubiquitin specific peptidase 8 -2.39684
GSPT1 G1 to S phase transition 1 -2.38993
TCN2 transcobalamin II -2.38639
NCKAP1 NCK-associated protein 1 -2.376
TXN2 thioredoxin 2 -2.36517
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 -2.34875
TST thiosulfate sulfurtransferase (rhodanese) -2.3383
SNX4 sorting nexin 4 -2.33084
GPS1 G protein pathway suppressor 1 -2.32009
RABGGTA Rab geranylgeranyltransferase, alpha subunit -2.30071
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -2.30021
ABHD5 abhydrolase domain containing 5 -2.28826
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.2825
TRIM28 tripartite motif containing 28 -2.28022
TM9SF1 transmembrane 9 superfamily member 1 -2.26902
RPL6 ribosomal protein L6 -2.2679
SOD1 superoxide dismutase 1, soluble -2.26103
MEN1 multiple endocrine neoplasia I -2.24809
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) -2.24342
PDK3 pyruvate dehydrogenase kinase, isozyme 3 -2.24168
SLC6A18 solute carrier family 6 (neutral amino acid transporter), member 18 -2.2329
CBFB core-binding factor, beta subunit -2.21296
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -2.21189
ZMYND11 zinc finger, MYND-type containing 11 -2.20535
TMOD3 tropomodulin 3 (ubiquitous) -2.19922
PON2 paraoxonase 2 -2.19381
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4 -2.19275
RPL8 ribosomal protein L8 -2.18812
MED28 mediator complex subunit 28 -2.1876
WBP5 WW domain binding protein 5 -2.18758
FH fumarate hydratase -2.18296
RAB8A RAB8A, member RAS oncogene family -2.17721
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -2.17354
GM2A GM2 ganglioside activator -2.16688
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.16464
JAGN1 jagunal homolog 1 (Drosophila) -2.16304
LDHA lactate dehydrogenase A -2.16254
PPT2 palmitoyl-protein thioesterase 2 -2.1611
TP53INP1 tumor protein p53 inducible nuclear protein 1 -2.15066
NECAP2 NECAP endocytosis associated 2 -2.14746
TPMT thiopurine S-methyltransferase -2.14087
GINM1 glycoprotein integral membrane 1 -2.12239
ANAPC5 anaphase promoting complex subunit 5 -2.11999
G6PC3 glucose 6 phosphatase, catalytic, 3 -2.11747
RCE1 Ras converting CAAX endopeptidase 1 -2.11402
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -2.09956
YBX1 Y box binding protein 1 -2.09145
BBS4 Bardet-Biedl syndrome 4 -2.08606
CIDEB cell death-inducing DFFA-like effector b -2.06827
GUSB glucuronidase, beta -2.06523
C12ORF57 chromosome 12 open reading frame 57 -2.05775
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.0298
GPC4 glypican 4 -2.0297
MLX MLX, MAX dimerization protein -2.02669
INPP5J inositol polyphosphate-5-phosphatase J -2.02551
REEP5 receptor accessory protein 5 -2.02412
SETD8 SET domain containing (lysine methyltransferase) 8 -2.02356
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.02176
SRSF4 serine/arginine-rich splicing factor 4 -2.01751
KRTCAP2 keratinocyte associated protein 2 -2.01717
MRPL45 mitochondrial ribosomal protein L45 -2.01601
PRDX1 peroxiredoxin 1 -1.99639
SPNS1 spinster homolog 1 (Drosophila) -1.99114
VAMP8 vesicle-associated membrane protein 8 -1.98985
STX5 syntaxin 5 -1.97707
DPP7 dipeptidyl-peptidase 7 -1.97065
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -1.95669
HIST1H2BI histone cluster 1, H2bi -1.94614
SURF1 surfeit 1 -1.94073
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -1.93084
CLK3 CDC-like kinase 3 -1.91711
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -1.91399
ANGEL2 angel homolog 2 (Drosophila) -1.90623
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 -1.90617
C2ORF49 chromosome 2 open reading frame 49 -1.9017
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -1.90118
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -1.89992
MAEA macrophage erythroblast attacher -1.89952
SCPEP1 serine carboxypeptidase 1 -1.89562
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -1.89486
RTN3 reticulon 3 -1.89448
SNX3 sorting nexin 3 -1.87413
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -1.87193
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.86417
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -1.86328
CDAN1 codanin 1 -1.85904
ETHE1 ethylmalonic encephalopathy 1 -1.85454
ZBTB20 zinc finger and BTB domain containing 20 -1.85391
STBD1 starch binding domain 1 -1.85248
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 -1.85244
ATP11A ATPase, class VI, type 11A -1.852
C16ORF13 chromosome 16 open reading frame 13 -1.85099
RPS26 ribosomal protein S26 -1.83783
ACOT9 acyl-CoA thioesterase 9 -1.83776
SEC13 SEC13 homolog (S. cerevisiae) -1.8352
TPP1 tripeptidyl peptidase I -1.83394
EFNB2 ephrin-B2 -1.83045
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 -1.8215
TARS threonyl-tRNA synthetase -1.81158
CDH16 cadherin 16, KSP-cadherin -1.785
NUP62 nucleoporin 62kDa -1.78105
EIF3D eukaryotic translation initiation factor 3, subunit D -1.77866
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.77809
GDAP2 ganglioside induced differentiation associated protein 2 -1.77792
LAMP1 lysosomal-associated membrane protein 1 -1.77644
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 -1.75496
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -1.74835
PNRC2 proline-rich nuclear receptor coactivator 2 -1.74464
CSF1R colony stimulating factor 1 receptor -1.74427
RPL18 ribosomal protein L18 -1.74339
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -1.74334
HNRNPM heterogeneous nuclear ribonucleoprotein M -1.7385
IRAK1 interleukin-1 receptor-associated kinase 1 -1.73784
PKP4 plakophilin 4 -1.73695
SFR1 SWI5-dependent recombination repair 1 -1.73599
RPS11 ribosomal protein S11 -1.73478
PUM2 pumilio RNA-binding family member 2 -1.7318
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -1.72879
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -1.71687
GTPBP4 GTP binding protein 4 -1.71333
SEC24C SEC24 family member C -1.71313
UIMC1 ubiquitin interaction motif containing 1 -1.71072
CSDE1 cold shock domain containing E1, RNA-binding -1.70756
TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa -1.70741
RBM8A RNA binding motif protein 8A -1.70503
CTSH cathepsin H -1.70392
EGLN2 egl-9 family hypoxia-inducible factor 2 -1.70288
RAB4A RAB4A, member RAS oncogene family -1.69864
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -1.68788
TMEM176B transmembrane protein 176B -1.67905
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 -1.6758
COPE coatomer protein complex, subunit epsilon -1.67413
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -1.6702
TOP1 topoisomerase (DNA) I -1.66038
CPNE3 copine III -1.65025
DQX1 DEAQ box RNA-dependent ATPase 1 -1.64897
RPL3 ribosomal protein L3 -1.64874
CD99L2 CD99 molecule-like 2 -1.64641
PRDX5 peroxiredoxin 5 -1.64551
HSF1 heat shock transcription factor 1 -1.64177
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -1.64116
SUMO1 small ubiquitin-like modifier 1 -1.64109
CXXC1 CXXC finger protein 1 -1.64083
AMMECR1L AMMECR1-like -1.64071
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -1.63908
NDEL1 nudE neurodevelopment protein 1-like 1 -1.63884
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -1.63639
GUK1 guanylate kinase 1 -1.63386
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -1.63362
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -1.63116
ACTN4 actinin, alpha 4 -1.63068
KIAA1191 KIAA1191 -1.62943
TRAPPC2L trafficking protein particle complex 2-like -1.62538
UQCRC1 ubiquinol-cytochrome c reductase core protein I -1.62475
RPS7 ribosomal protein S7 -1.62468
COX17 COX17 cytochrome c oxidase copper chaperone -1.6243
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -1.62392
NUP54 nucleoporin 54kDa -1.62034
PPP1R15B protein phosphatase 1, regulatory subunit 15B -1.61783
GGCT gamma-glutamylcyclotransferase -1.61496
SLMO2 slowmo homolog 2 (Drosophila) -1.61142
SRP9 signal recognition particle 9kDa -1.60743
HPN hepsin -1.60547
ACIN1 apoptotic chromatin condensation inducer 1 -1.60205
CS citrate synthase -1.59652
FAM192A family with sequence similarity 192, member A -1.58496
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 -1.58218
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.57832
CYHR1 cysteine/histidine-rich 1 -1.57151
WDR81 WD repeat domain 81 -1.57086
FOLR1 folate receptor 1 (adult) -1.57074
ROMO1 reactive oxygen species modulator 1 -1.56974
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) -1.56824
POLD2 polymerase (DNA directed), delta 2, accessory subunit -1.56245
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -1.56055
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -1.55841
FAM50A family with sequence similarity 50, member A -1.55698
ABLIM1 actin binding LIM protein 1 -1.55382
RPS23 ribosomal protein S23 -1.5488
C8ORF33 chromosome 8 open reading frame 33 -1.54831
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -1.54751
MAP2K5 mitogen-activated protein kinase kinase 5 -1.54746
RPL13 ribosomal protein L13 -1.54469
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -1.54373
NUCB1 nucleobindin 1 -1.53748
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase -1.53201
SNRK SNF related kinase -1.53072
USP5 ubiquitin specific peptidase 5 (isopeptidase T) -1.53017
TEX264 testis expressed 264 -1.52926
PPIA peptidylprolyl isomerase A (cyclophilin A) -1.52613
NFIB nuclear factor I/B -1.51462
SPOP speckle-type POZ protein -1.51388
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 -1.51312
DPP8 dipeptidyl-peptidase 8 -1.51271
TEC tec protein tyrosine kinase -1.50643
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -1.50335
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -1.49817
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 -1.49813
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -1.49624
PGM1 phosphoglucomutase 1 -1.4946
DAO D-amino-acid oxidase -1.49441
PPP4C protein phosphatase 4, catalytic subunit -1.49417
CACUL1 CDK2-associated, cullin domain 1 -1.49389
COMMD3-BMI1 COMMD3-BMI1 readthrough -1.49387
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -1.49335
TRIP6 thyroid hormone receptor interactor 6 -1.49201
TRAPPC4 trafficking protein particle complex 4 -1.49025
PDZD11 PDZ domain containing 11 -1.49021
TMED4 transmembrane emp24 protein transport domain containing 4 -1.48072
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.47418
LEMD2 LEM domain containing 2 -1.47325
RNMTL1 RNA methyltransferase like 1 -1.46492
OSTF1 osteoclast stimulating factor 1 -1.46483
PNP purine nucleoside phosphorylase -1.46453
MYEF2 myelin expression factor 2 -1.45898
UBAP2 ubiquitin associated protein 2 -1.45846
CNOT1 CCR4-NOT transcription complex, subunit 1 -1.45503
PGK1 phosphoglycerate kinase 1 -1.45222
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 -1.4399
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -1.43814
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -1.4359
CRTAP cartilage associated protein -1.4332
OSBP oxysterol binding protein -1.43133
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -1.43008
ATP13A1 ATPase type 13A1 -1.42752
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -1.42509
DSTN destrin (actin depolymerizing factor) -1.42499
PRKCSH protein kinase C substrate 80K-H -1.42491
ARAF A-Raf proto-oncogene, serine/threonine kinase -1.42391
API5 apoptosis inhibitor 5 -1.4235
LRP10 low density lipoprotein receptor-related protein 10 -1.41933
AAMP angio-associated, migratory cell protein -1.41737
AKIRIN2 akirin 2 -1.41659
SPRYD4 SPRY domain containing 4 -1.41443
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -1.4144
COPA coatomer protein complex, subunit alpha -1.41413
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -1.41264
SLC22A25 solute carrier family 22, member 25 -1.41129
DOCK5 dedicator of cytokinesis 5 -1.41064
NDFIP1 Nedd4 family interacting protein 1 -1.40608
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 -1.40498
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -1.40465
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -1.40285
TMEM150A transmembrane protein 150A -1.40057
JTB jumping translocation breakpoint -1.4
MBD3 methyl-CpG binding domain protein 3 -1.39979