Type 2 diabetes mellitus_Pancreas_GSE2470 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2470
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Genes

600 genes differentially expressed during Type 2 diabetes mellitus_Pancreas_GSE2470 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 4.10823
ETFDH electron-transferring-flavoprotein dehydrogenase 4.06518
POGLUT1 protein O-glucosyltransferase 1 3.82313
BDKRB2 bradykinin receptor B2 3.70334
PRPH2 peripherin 2 (retinal degeneration, slow) 3.59819
ZNF362 zinc finger protein 362 3.52538
MYLK2 myosin light chain kinase 2 3.48973
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 3.38611
LCN2 lipocalin 2 3.34655
MANBAL mannosidase, beta A, lysosomal-like 3.32219
CREB1 cAMP responsive element binding protein 1 3.28418
PCM1 pericentriolar material 1 3.20221
TMEM109 transmembrane protein 109 3.08815
CTRC chymotrypsin C (caldecrin) 3.07718
LHX5 LIM homeobox 5 3.04233
EIF3D eukaryotic translation initiation factor 3, subunit D 2.88932
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 2.84084
RPL9 ribosomal protein L9 2.77234
SECISBP2L SECIS binding protein 2-like 2.69306
CP ceruloplasmin (ferroxidase) 2.67862
EIF1AD eukaryotic translation initiation factor 1A domain containing 2.67541
ANXA7 annexin A7 2.63859
HMOX2 heme oxygenase 2 2.58764
BUB3 BUB3 mitotic checkpoint protein 2.47761
MRPL36 mitochondrial ribosomal protein L36 2.46721
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 2.44236
A2M alpha-2-macroglobulin 2.39741
DSC2 desmocollin 2 2.36879
FAM174A family with sequence similarity 174, member A 2.33732
SLC26A5 solute carrier family 26 (anion exchanger), member 5 2.32065
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 2.31169
PNLIPRP1 pancreatic lipase-related protein 1 2.28508
URGCP upregulator of cell proliferation 2.27854
PHB prohibitin 2.26137
LIPT2 lipoyl(octanoyl) transferase 2 (putative) 2.24562
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 2.21663
ACER2 alkaline ceramidase 2 2.21545
ADAR adenosine deaminase, RNA-specific 2.21533
FGG fibrinogen gamma chain 2.18711
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) 2.17173
PPA2 pyrophosphatase (inorganic) 2 2.13972
GNG5 guanine nucleotide binding protein (G protein), gamma 5 2.10178
CLPS colipase, pancreatic 2.10089
PTH parathyroid hormone 2.07027
SSRP1 structure specific recognition protein 1 2.05455
TRIM33 tripartite motif containing 33 2.02667
TGM4 transglutaminase 4 2.02663
AIDA axin interactor, dorsalization associated 1.98356
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.97258
MAP3K11 mitogen-activated protein kinase kinase kinase 11 1.95829
FAAH fatty acid amide hydrolase 1.95051
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 1.92624
OGG1 8-oxoguanine DNA glycosylase 1.92426
FGF4 fibroblast growth factor 4 1.89521
PPP2R2D protein phosphatase 2, regulatory subunit B, delta 1.89065
ACADL acyl-CoA dehydrogenase, long chain 1.89034
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.86354
FAM118A family with sequence similarity 118, member A 1.85803
FBXO18 F-box protein, helicase, 18 1.84283
SRP68 signal recognition particle 68kDa 1.84199
DLC1 DLC1 Rho GTPase activating protein 1.84088
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 1.83036
NT5M 5',3'-nucleotidase, mitochondrial 1.82844
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 1.82742
REEP4 receptor accessory protein 4 1.82365
GDF10 growth differentiation factor 10 1.80846
GPR20 G protein-coupled receptor 20 1.78773
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 1.76117
MAST3 microtubule associated serine/threonine kinase 3 1.73565
PRSS35 protease, serine, 35 1.7245
PAN3 PAN3 poly(A) specific ribonuclease subunit 1.72301
PRMT2 protein arginine methyltransferase 2 1.71964
ECH1 enoyl CoA hydratase 1, peroxisomal 1.70924
PYGB phosphorylase, glycogen; brain 1.70042
PSKH1 protein serine kinase H1 1.67094
SYNJ2BP synaptojanin 2 binding protein 1.67007
PMFBP1 polyamine modulated factor 1 binding protein 1 1.65204
STARD7 StAR-related lipid transfer (START) domain containing 7 1.64793
ETFA electron-transfer-flavoprotein, alpha polypeptide 1.64194
GLRX5 glutaredoxin 5 1.63094
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.62093
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 1.61957
ICA1 islet cell autoantigen 1, 69kDa 1.6055
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 1.59728
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 1.58954
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 1.58799
FCF1 FCF1 rRNA-processing protein 1.57266
DTNBP1 dystrobrevin binding protein 1 1.56154
CXXC4 CXXC finger protein 4 1.55226
TAOK2 TAO kinase 2 1.53865
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 1.53777
UBE4A ubiquitination factor E4A 1.52826
CHD6 chromodomain helicase DNA binding protein 6 1.52737
FBLN2 fibulin 2 1.52633
KIDINS220 kinase D-interacting substrate, 220kDa 1.50677
PHAX phosphorylated adaptor for RNA export 1.50577
SNX14 sorting nexin 14 1.49317
PRKCD protein kinase C, delta 1.48968
STAG3 stromal antigen 3 1.48526
PRR14L proline rich 14-like 1.47711
INPP5J inositol polyphosphate-5-phosphatase J 1.47581
RPL5 ribosomal protein L5 1.47301
FDX1 ferredoxin 1 1.47058
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 1.45137
GLUD1 glutamate dehydrogenase 1 1.43816
PRIM2 primase, DNA, polypeptide 2 (58kDa) 1.4376
ALKBH2 alkB, alkylation repair homolog 2 (E. coli) 1.42826
GPR19 G protein-coupled receptor 19 1.42786
CPNE1 copine I 1.42514
ASCC1 activating signal cointegrator 1 complex subunit 1 1.42298
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 1.42273
FBXO11 F-box protein 11 1.42017
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 1.405
S1PR3 sphingosine-1-phosphate receptor 3 1.39985
ACTR10 actin-related protein 10 homolog (S. cerevisiae) 1.3963
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 1.39479
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1.39457
INHBB inhibin, beta B 1.39257
PPCDC phosphopantothenoylcysteine decarboxylase 1.38213
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 1.37555
CCDC51 coiled-coil domain containing 51 1.3686
PPIE peptidylprolyl isomerase E (cyclophilin E) 1.36644
RPS12 ribosomal protein S12 1.36463
MAML1 mastermind-like 1 (Drosophila) 1.36139
ORC2 origin recognition complex, subunit 2 1.35882
DNASE1 deoxyribonuclease I 1.32353
CD300A CD300a molecule 1.30716
SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 1.30421
ADPRH ADP-ribosylarginine hydrolase 1.30234
FAM136A family with sequence similarity 136, member A 1.29987
RCOR2 REST corepressor 2 1.29958
RWDD1 RWD domain containing 1 1.29424
FUNDC1 FUN14 domain containing 1 1.28863
INPP5B inositol polyphosphate-5-phosphatase, 75kDa 1.28645
TXNIP thioredoxin interacting protein 1.2858
GLRX glutaredoxin (thioltransferase) 1.28155
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 1.27912
ZNF746 zinc finger protein 746 1.27822
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 1.27729
GLIPR1 GLI pathogenesis-related 1 1.2698
ANAPC11 anaphase promoting complex subunit 11 1.2661
GLCCI1 glucocorticoid induced 1 1.26301
KIAA0430 KIAA0430 1.25759
SHANK2 SH3 and multiple ankyrin repeat domains 2 1.25698
BIRC2 baculoviral IAP repeat containing 2 1.25281
HIP1R huntingtin interacting protein 1 related 1.25183
PIANP PILR alpha associated neural protein 1.25104
NFE2L1 nuclear factor, erythroid 2-like 1 1.2503
ATAD2 ATPase family, AAA domain containing 2 1.24188
MRPS25 mitochondrial ribosomal protein S25 1.24005
MRPL44 mitochondrial ribosomal protein L44 1.2399
ARID3B AT rich interactive domain 3B (BRIGHT-like) 1.23804
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 1.23582
PRL prolactin 1.2285
BLVRA biliverdin reductase A 1.22065
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 1.21823
L3MBTL2 l(3)mbt-like 2 (Drosophila) 1.21432
TSEN15 TSEN15 tRNA splicing endonuclease subunit 1.21323
CPT1A carnitine palmitoyltransferase 1A (liver) 1.20724
ZNF513 zinc finger protein 513 1.1982
SYMPK symplekin 1.19278
C1QBP complement component 1, q subcomponent binding protein 1.1926
TMIGD1 transmembrane and immunoglobulin domain containing 1 1.18809
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 1.18327
MLYCD malonyl-CoA decarboxylase 1.17975
ALDOB aldolase B, fructose-bisphosphate 1.17721
RAB23 RAB23, member RAS oncogene family 1.17681
CDON cell adhesion associated, oncogene regulated 1.17353
ANAPC2 anaphase promoting complex subunit 2 1.16831
ANKRD37 ankyrin repeat domain 37 1.16734
UMPS uridine monophosphate synthetase 1.16708
ARF3 ADP-ribosylation factor 3 1.16623
MRPS18A mitochondrial ribosomal protein S18A 1.15733
DIABLO diablo, IAP-binding mitochondrial protein 1.14825
SHANK1 SH3 and multiple ankyrin repeat domains 1 1.14755
PPAN peter pan homolog (Drosophila) 1.14717
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 1.14475
NOP10 NOP10 ribonucleoprotein 1.14448
APOOL apolipoprotein O-like 1.14284
DEXI Dexi homolog (mouse) 1.14145
CYP8B1 cytochrome P450, family 8, subfamily B, polypeptide 1 1.13825
EXOSC7 exosome component 7 1.13139
IRF3 interferon regulatory factor 3 1.13045
PNISR PNN-interacting serine/arginine-rich protein 1.13037
IP6K2 inositol hexakisphosphate kinase 2 1.1283
TROAP trophinin associated protein 1.10963
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa 1.10748
EPDR1 ependymin related 1 1.10447
ZBTB48 zinc finger and BTB domain containing 48 1.10406
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 1.10371
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase 1.10364
ASPN asporin 1.09971
AP4B1 adaptor-related protein complex 4, beta 1 subunit 1.0981
EFHD2 EF-hand domain family, member D2 1.09666
SMC3 structural maintenance of chromosomes 3 1.09496
RELT RELT tumor necrosis factor receptor 1.0947
ENPEP glutamyl aminopeptidase (aminopeptidase A) 1.09328
RBM7 RNA binding motif protein 7 1.09297
MTSS1 metastasis suppressor 1 1.09286
TRPM8 transient receptor potential cation channel, subfamily M, member 8 1.09274
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 1.09069
PLAGL1 pleiomorphic adenoma gene-like 1 1.08993
XPOT exportin, tRNA 1.08594
RET ret proto-oncogene 1.08054
ADCK3 aarF domain containing kinase 3 1.07979
KLF10 Kruppel-like factor 10 1.07915
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 1.07533
SAYSD1 SAYSVFN motif domain containing 1 1.06887
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 1.06864
DTD1 D-tyrosyl-tRNA deacylase 1 1.06779
GPSM2 G-protein signaling modulator 2 1.06678
POLB polymerase (DNA directed), beta 1.06662
RPL26 ribosomal protein L26 1.06601
ASRGL1 asparaginase like 1 1.06415
TCEA1 transcription elongation factor A (SII), 1 1.06219
CUL1 cullin 1 1.05299
CCL20 chemokine (C-C motif) ligand 20 1.05201
SEPT3 septin 3 1.05186
NCOR1 nuclear receptor corepressor 1 1.04577
FAHD1 fumarylacetoacetate hydrolase domain containing 1 1.04526
TTYH1 tweety family member 1 1.04193
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 1.04037
ECHDC3 enoyl CoA hydratase domain containing 3 1.03766
SLK STE20-like kinase 1.035
MRPL34 mitochondrial ribosomal protein L34 1.03104
RARG retinoic acid receptor, gamma 1.02966
IL11RA interleukin 11 receptor, alpha 1.02957
SMAGP small cell adhesion glycoprotein 1.0287
ZNF609 zinc finger protein 609 1.02841
ECM1 extracellular matrix protein 1 1.02702
CABIN1 calcineurin binding protein 1 1.02643
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 1.02262
EXOC4 exocyst complex component 4 1.02124
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 1.0189
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 1.01873
RBM45 RNA binding motif protein 45 1.01721
SNX4 sorting nexin 4 1.01388
MXD1 MAX dimerization protein 1 1.01037
PFKP phosphofructokinase, platelet 1.00999
SOS2 son of sevenless homolog 2 (Drosophila) 1.00433
RPL12 ribosomal protein L12 1.00287
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 1.00228
DRP2 dystrophin related protein 2 1.00224
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 1.00098
SCARB1 scavenger receptor class B, member 1 1.00019
USP47 ubiquitin specific peptidase 47 0.998011
BCL2L1 BCL2-like 1 0.996963
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.994397
AMHR2 anti-Mullerian hormone receptor, type II 0.991561
GJB4 gap junction protein, beta 4, 30.3kDa 0.991452
TRIB3 tribbles pseudokinase 3 0.988044
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.987601
SEPT4 septin 4 0.985355
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.984312
RPL7A ribosomal protein L7a 0.978983
TPT1 tumor protein, translationally-controlled 1 0.978631
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.978571
PCBP4 poly(rC) binding protein 4 0.976354
GLS2 glutaminase 2 (liver, mitochondrial) 0.974538
ZFP36L1 ZFP36 ring finger protein-like 1 0.974162
EDN1 endothelin 1 0.97409
PPAT phosphoribosyl pyrophosphate amidotransferase 0.970451
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 0.968471
FAM114A1 family with sequence similarity 114, member A1 0.967244
KDM2A lysine (K)-specific demethylase 2A 0.967171
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.966695
RPS8 ribosomal protein S8 0.964708
FAM53A family with sequence similarity 53, member A 0.963086
GDF15 growth differentiation factor 15 0.961635
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 0.959745
TLK2 tousled-like kinase 2 0.959702
RXRB retinoid X receptor, beta 0.959088
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type 0.958797
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) 0.954931
PRSS22 protease, serine, 22 0.95366
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.952906
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) 0.951104
PAMR1 peptidase domain containing associated with muscle regeneration 1 0.950242
NUP205 nucleoporin 205kDa 0.940527
TTC5 tetratricopeptide repeat domain 5 0.935389
ADHFE1 alcohol dehydrogenase, iron containing, 1 0.931314
LACTB2 lactamase, beta 2 0.929507
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.927823
RBM14 RNA binding motif protein 14 0.923327
CDK5 cyclin-dependent kinase 5 0.917303
COG2 component of oligomeric golgi complex 2 0.912632
LIG1 ligase I, DNA, ATP-dependent 0.912107
LMO7 LIM domain 7 0.911443
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.908717
NDRG2 NDRG family member 2 0.903373
PDHX pyruvate dehydrogenase complex, component X 0.90321
MTX1 metaxin 1 0.902179
DCAF17 DDB1 and CUL4 associated factor 17 0.900894
USP24 ubiquitin specific peptidase 24 0.900828
TMX2 thioredoxin-related transmembrane protein 2 0.899232
BZW2 basic leucine zipper and W2 domains 2 0.898093
FOXJ1 forkhead box J1 0.897207
PEF1 penta-EF-hand domain containing 1 0.893263
MADD MAP-kinase activating death domain 0.893111
SKAP2 src kinase associated phosphoprotein 2 0.889381

decreased expression

Symbol Name Standardized Value
MRPS24 mitochondrial ribosomal protein S24 -5.21894
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2) -4.0865
PTPRS protein tyrosine phosphatase, receptor type, S -4.03877
OMD osteomodulin -4.00257
ETNK2 ethanolamine kinase 2 -3.80643
LRRC8D leucine rich repeat containing 8 family, member D -3.79289
IER5 immediate early response 5 -3.72878
PSIP1 PC4 and SFRS1 interacting protein 1 -3.71732
INSIG2 insulin induced gene 2 -3.46282
CERS2 ceramide synthase 2 -3.16709
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) -3.16486
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) -3.12471
RNF166 ring finger protein 166 -3.00524
BACE2 beta-site APP-cleaving enzyme 2 -2.99744
RASIP1 Ras interacting protein 1 -2.94625
NUPL1 nucleoporin like 1 -2.94269
CCKBR cholecystokinin B receptor -2.93588
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 -2.85466
SOX4 SRY (sex determining region Y)-box 4 -2.71931
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide -2.70047
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.68382
AGTRAP angiotensin II receptor-associated protein -2.68199
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit -2.66888
DOCK8 dedicator of cytokinesis 8 -2.63723
FABP12 fatty acid binding protein 12 -2.62843
BRD8 bromodomain containing 8 -2.60067
CASC4 cancer susceptibility candidate 4 -2.59165
BMP15 bone morphogenetic protein 15 -2.5691
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 -2.54005
LRRC14B leucine rich repeat containing 14B -2.50633
ADAP1 ArfGAP with dual PH domains 1 -2.50331
TRIM3 tripartite motif containing 3 -2.48505
TNRC6A trinucleotide repeat containing 6A -2.42621
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 -2.42301
GTPBP2 GTP binding protein 2 -2.37494
SAT2 spermidine/spermine N1-acetyltransferase family member 2 -2.37133
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3 -2.35829
MAOB monoamine oxidase B -2.35049
ADK adenosine kinase -2.34824
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) -2.328
NEO1 neogenin 1 -2.31238
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 -2.26937
LENG8 leukocyte receptor cluster (LRC) member 8 -2.24245
DUSP9 dual specificity phosphatase 9 -2.22689
SCARF2 scavenger receptor class F, member 2 -2.22613
CUZD1 CUB and zona pellucida-like domains 1 -2.22602
PDIA2 protein disulfide isomerase family A, member 2 -2.17807
LAMA3 laminin, alpha 3 -2.16811
FANCE Fanconi anemia, complementation group E -2.16466
MAMDC2 MAM domain containing 2 -2.16127
MAST2 microtubule associated serine/threonine kinase 2 -2.14657
PDE7A phosphodiesterase 7A -2.1241
PQLC1 PQ loop repeat containing 1 -2.10188
NICN1 nicolin 1 -2.09623
TOP2A topoisomerase (DNA) II alpha 170kDa -2.09438
SETD4 SET domain containing 4 -2.08595
NR0B2 nuclear receptor subfamily 0, group B, member 2 -2.08572
GRIA4 glutamate receptor, ionotropic, AMPA 4 -2.06069
CRELD1 cysteine-rich with EGF-like domains 1 -2.04849
LRP11 low density lipoprotein receptor-related protein 11 -2.01911
ZNF346 zinc finger protein 346 -1.99656
BARD1 BRCA1 associated RING domain 1 -1.97298
ZNF324 zinc finger protein 324 -1.96138
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -1.96117
NIP7 NIP7, nucleolar pre-rRNA processing protein -1.94949
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled -1.92447
PDRG1 p53 and DNA-damage regulated 1 -1.90831
FAM120C family with sequence similarity 120C -1.90696
ACRV1 acrosomal vesicle protein 1 -1.88544
RARB retinoic acid receptor, beta -1.88491
ZFPM1 zinc finger protein, FOG family member 1 -1.8845
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 -1.88211
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) -1.87188
MCM3 minichromosome maintenance complex component 3 -1.86117
AP1S3 adaptor-related protein complex 1, sigma 3 subunit -1.82512
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) -1.82341
CHD2 chromodomain helicase DNA binding protein 2 -1.82281
MRPL28 mitochondrial ribosomal protein L28 -1.82036
PLD4 phospholipase D family, member 4 -1.81743
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.81311
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 -1.79867
LAMA5 laminin, alpha 5 -1.79438
SYT3 synaptotagmin III -1.79236
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 -1.792
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B -1.78437
SCN5A sodium channel, voltage gated, type V alpha subunit -1.77103
HRH1 histamine receptor H1 -1.76182
IGFBP5 insulin-like growth factor binding protein 5 -1.75531
SCAPER S-phase cyclin A-associated protein in the ER -1.74545
ENY2 enhancer of yellow 2 homolog (Drosophila) -1.74414
NGFR nerve growth factor receptor -1.7247
DRG2 developmentally regulated GTP binding protein 2 -1.70687
TMEM171 transmembrane protein 171 -1.70645
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -1.70567
PROC protein C (inactivator of coagulation factors Va and VIIIa) -1.70281
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 -1.68987
EGLN2 egl-9 family hypoxia-inducible factor 2 -1.68467
VKORC1 vitamin K epoxide reductase complex, subunit 1 -1.68166
PNMAL2 paraneoplastic Ma antigen family-like 2 -1.67757
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F -1.67016
GLS glutaminase -1.66916
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -1.66769
METTL3 methyltransferase like 3 -1.65277
ABHD13 abhydrolase domain containing 13 -1.64048
LAMC1 laminin, gamma 1 (formerly LAMB2) -1.63492
LARS leucyl-tRNA synthetase -1.63425
HOXA11 homeobox A11 -1.63293
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3 -1.6321
PEX6 peroxisomal biogenesis factor 6 -1.6292
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 -1.62613
CFL2 cofilin 2 (muscle) -1.61346
DOHH deoxyhypusine hydroxylase/monooxygenase -1.59166
ELMOD1 ELMO/CED-12 domain containing 1 -1.56863
LY6H lymphocyte antigen 6 complex, locus H -1.5671
BAG5 BCL2-associated athanogene 5 -1.56555
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -1.55029
RYK receptor-like tyrosine kinase -1.54859
NTNG1 netrin G1 -1.54302
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 -1.53737
PALM paralemmin -1.5344
CPEB1 cytoplasmic polyadenylation element binding protein 1 -1.53328
SHROOM1 shroom family member 1 -1.52588
PLLP plasmolipin -1.52284
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -1.52029
MYO10 myosin X -1.52022
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 -1.51583
PRRX1 paired related homeobox 1 -1.51254
PKD1 polycystic kidney disease 1 (autosomal dominant) -1.5107
EPHA8 EPH receptor A8 -1.50509
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) -1.4996
THRAP3 thyroid hormone receptor associated protein 3 -1.49045
FOLR2 folate receptor 2 (fetal) -1.48567
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1 -1.48025
USP36 ubiquitin specific peptidase 36 -1.47781
SCHIP1 schwannomin interacting protein 1 -1.46348
TRAK1 trafficking protein, kinesin binding 1 -1.45555
MANEA mannosidase, endo-alpha -1.45468
HYAL2 hyaluronoglucosaminidase 2 -1.45209
SS18 synovial sarcoma translocation, chromosome 18 -1.45011
GLE1 GLE1 RNA export mediator -1.44896
AK1 adenylate kinase 1 -1.4478
TFF2 trefoil factor 2 -1.44627
RIOK2 RIO kinase 2 -1.44474
PNLIPRP2 pancreatic lipase-related protein 2 -1.44338
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -1.4395
LAMP1 lysosomal-associated membrane protein 1 -1.43318
MYOM2 myomesin 2 -1.42929
FUCA1 fucosidase, alpha-L- 1, tissue -1.42903
ZFHX2 zinc finger homeobox 2 -1.42574
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal -1.42462
SYCP3 synaptonemal complex protein 3 -1.42448
ACOT8 acyl-CoA thioesterase 8 -1.41974
ERCC2 excision repair cross-complementation group 2 -1.41685
CEL carboxyl ester lipase -1.41533
RSBN1 round spermatid basic protein 1 -1.41242
GHR growth hormone receptor -1.41162
PIEZO2 piezo-type mechanosensitive ion channel component 2 -1.40748
ZC3HC1 zinc finger, C3HC-type containing 1 -1.40008
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) -1.39977
NOA1 nitric oxide associated 1 -1.39724
MGST3 microsomal glutathione S-transferase 3 -1.39682
SLU7 SLU7 splicing factor homolog (S. cerevisiae) -1.38712
XBP1 X-box binding protein 1 -1.38708
SYCP2 synaptonemal complex protein 2 -1.38451
TNPO2 transportin 2 -1.38001
HUNK hormonally up-regulated Neu-associated kinase -1.37735
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) -1.37538
CDC16 cell division cycle 16 -1.36471
RASA1 RAS p21 protein activator (GTPase activating protein) 1 -1.36184
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 -1.35316
NFS1 NFS1 cysteine desulfurase -1.35221
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -1.35101
TEX101 testis expressed 101 -1.34924
SLC22A17 solute carrier family 22, member 17 -1.34727
DDR2 discoidin domain receptor tyrosine kinase 2 -1.34508
SMG9 SMG9 nonsense mediated mRNA decay factor -1.34361
MKL1 megakaryoblastic leukemia (translocation) 1 -1.34351
MATK megakaryocyte-associated tyrosine kinase -1.343
GOSR1 golgi SNAP receptor complex member 1 -1.33326
CAPN6 calpain 6 -1.3288
ACSM5 acyl-CoA synthetase medium-chain family member 5 -1.31751
SARS seryl-tRNA synthetase -1.31518
GBAS glioblastoma amplified sequence -1.3141
FAM171A2 family with sequence similarity 171, member A2 -1.30489
HIST1H2BG histone cluster 1, H2bg -1.30324
PEX12 peroxisomal biogenesis factor 12 -1.29674
NSUN5 NOP2/Sun domain family, member 5 -1.29671
CD63 CD63 molecule -1.29667
TUBA8 tubulin, alpha 8 -1.29509
GJC2 gap junction protein, gamma 2, 47kDa -1.29496
TMEM42 transmembrane protein 42 -1.29164
ACTA1 actin, alpha 1, skeletal muscle -1.28674
GPATCH1 G patch domain containing 1 -1.28435
NOTCH2 notch 2 -1.27591
RUNDC3A RUN domain containing 3A -1.27481
ZNF317 zinc finger protein 317 -1.27471
CTC1 CTS telomere maintenance complex component 1 -1.27027
FIBP fibroblast growth factor (acidic) intracellular binding protein -1.26444
HELLS helicase, lymphoid-specific -1.2641
LZTS1 leucine zipper, putative tumor suppressor 1 -1.26278
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -1.26251
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 -1.26143
PPME1 protein phosphatase methylesterase 1 -1.26132
UBTF upstream binding transcription factor, RNA polymerase I -1.26126
WDR46 WD repeat domain 46 -1.25968
RFX1 regulatory factor X, 1 (influences HLA class II expression) -1.2523
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -1.2422
GJB3 gap junction protein, beta 3, 31kDa -1.2399
EMX2 empty spiracles homeobox 2 -1.23784
CYBB cytochrome b-245, beta polypeptide -1.23451
ADAM19 ADAM metallopeptidase domain 19 -1.23096
INS insulin -1.22958
SIX1 SIX homeobox 1 -1.22682
ENKD1 enkurin domain containing 1 -1.22507
VSNL1 visinin-like 1 -1.22356
RPL7 ribosomal protein L7 -1.22331
TDP2 tyrosyl-DNA phosphodiesterase 2 -1.22304
MAN2B1 mannosidase, alpha, class 2B, member 1 -1.21924
ARL6IP6 ADP-ribosylation factor-like 6 interacting protein 6 -1.21704
FUCA2 fucosidase, alpha-L- 2, plasma -1.21645
TBX2 T-box 2 -1.21624
IL6 interleukin 6 -1.21119
GRIP2 glutamate receptor interacting protein 2 -1.20889
RASL11B RAS-like, family 11, member B -1.20819
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 -1.20775
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase -1.2073
TRADD TNFRSF1A-associated via death domain -1.20671
DIRAS1 DIRAS family, GTP-binding RAS-like 1 -1.2023
PDZD2 PDZ domain containing 2 -1.20151
LOC102723475 putative uncharacterized protein LOC388820 -1.20061
FBXL6 F-box and leucine-rich repeat protein 6 -1.19302
IL17D interleukin 17D -1.19061
PVR poliovirus receptor -1.19013
DIS3L DIS3 like exosome 3'-5' exoribonuclease -1.18995
HMMR hyaluronan-mediated motility receptor (RHAMM) -1.18497
FLYWCH1 FLYWCH-type zinc finger 1 -1.18053
SMC5 structural maintenance of chromosomes 5 -1.18042
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -1.1765
KCTD10 potassium channel tetramerization domain containing 10 -1.17548
FBXO32 F-box protein 32 -1.17479
ASZ1 ankyrin repeat, SAM and basic leucine zipper domain containing 1 -1.17428
HES5 hes family bHLH transcription factor 5 -1.17046
SCG2 secretogranin II -1.16981
PCID2 PCI domain containing 2 -1.16766
FAHD2B fumarylacetoacetate hydrolase domain containing 2B -1.16732
CCR2 chemokine (C-C motif) receptor 2 -1.16598
HIGD1B HIG1 hypoxia inducible domain family, member 1B -1.15632
IQGAP3 IQ motif containing GTPase activating protein 3 -1.15089
VAV1 vav 1 guanine nucleotide exchange factor -1.1494
RFC1 replication factor C (activator 1) 1, 145kDa -1.14909
FABP3 fatty acid binding protein 3, muscle and heart -1.14833
TTC28 tetratricopeptide repeat domain 28 -1.14461
TECPR1 tectonin beta-propeller repeat containing 1 -1.1437
MYO9B myosin IXB -1.14334
CRK v-crk avian sarcoma virus CT10 oncogene homolog -1.14217
FGFR2 fibroblast growth factor receptor 2 -1.14183
CLSTN1 calsyntenin 1 -1.14082
BRCA2 breast cancer 2, early onset -1.13984
NOL12 nucleolar protein 12 -1.13816
GMCL1 germ cell-less, spermatogenesis associated 1 -1.13562
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -1.13558
CX3CR1 chemokine (C-X3-C motif) receptor 1 -1.13081
PAPD4 PAP associated domain containing 4 -1.1254
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -1.12391
SNX6 sorting nexin 6 -1.12126
TMEM158 transmembrane protein 158 (gene/pseudogene) -1.1191
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 -1.11804
CPE carboxypeptidase E -1.11138
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -1.11016
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -1.10942
SPTA1 spectrin, alpha, erythrocytic 1 -1.1064
GRXCR1 glutaredoxin, cysteine rich 1 -1.10614
USP21 ubiquitin specific peptidase 21 -1.1039
PROM1 prominin 1 -1.09936
FAT1 FAT atypical cadherin 1 -1.09884
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 -1.09835
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -1.09558
WFS1 Wolfram syndrome 1 (wolframin) -1.09324
SH3GLB2 SH3-domain GRB2-like endophilin B2 -1.09221
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) -1.09165
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -1.08759
MFGE8 milk fat globule-EGF factor 8 protein -1.08605
THTPA thiamine triphosphatase -1.08234
ZEB1 zinc finger E-box binding homeobox 1 -1.07715
TTI2 TELO2 interacting protein 2 -1.07516
ZNF219 zinc finger protein 219 -1.07061
OXCT1 3-oxoacid CoA transferase 1 -1.06492
TCF19 transcription factor 19 -1.05432
CDCA4 cell division cycle associated 4 -1.05429
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 -1.05407
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -1.052
UBE2D1 ubiquitin-conjugating enzyme E2D 1 -1.05183
ADCK5 aarF domain containing kinase 5 -1.05019
SMAD7 SMAD family member 7 -1.04807
LHX2 LIM homeobox 2 -1.0461
SRC SRC proto-oncogene, non-receptor tyrosine kinase -1.04417
ISPD isoprenoid synthase domain containing -1.04362
ODF2 outer dense fiber of sperm tails 2 -1.04336
REXO2 RNA exonuclease 2 -1.04171
TMBIM6 transmembrane BAX inhibitor motif containing 6 -1.04086