Type 2 diabetes mellitus_Endocrine Pancreas - Islet Cell of Langerhans - Beta Cell (MMHCC)_GSE6428 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6428
Similar Terms
Downloads & Tools

Genes

600 genes differentially expressed during Type 2 diabetes mellitus_Endocrine Pancreas - Islet Cell of Langerhans - Beta Cell (MMHCC)_GSE6428 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 3.56461
TMEM141 transmembrane protein 141 3.2003
AP2M1 adaptor-related protein complex 2, mu 1 subunit 3.1587
SCCPDH saccharopine dehydrogenase (putative) 3.10626
UBC ubiquitin C 2.98357
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 2.91996
AHCYL1 adenosylhomocysteinase-like 1 2.89332
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 2.88026
THRAP3 thyroid hormone receptor associated protein 3 2.87984
HIGD2A HIG1 hypoxia inducible domain family, member 2A 2.78047
BCAS3 breast carcinoma amplified sequence 3 2.75483
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 2.71233
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 2.69789
PPME1 protein phosphatase methylesterase 1 2.68962
FTH1 ferritin, heavy polypeptide 1 2.66218
NFRKB nuclear factor related to kappaB binding protein 2.62941
SETD4 SET domain containing 4 2.59888
CLP1 cleavage and polyadenylation factor I subunit 1 2.57546
PAIP2 poly(A) binding protein interacting protein 2 2.57033
COMMD3 COMM domain containing 3 2.55274
SRI sorcin 2.53975
PARK7 parkinson protein 7 2.52057
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 2.51982
KRCC1 lysine-rich coiled-coil 1 2.51474
RBM4B RNA binding motif protein 4B 2.50766
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 2.49194
TMEM43 transmembrane protein 43 2.48523
ZNF22 zinc finger protein 22 2.47155
IFI35 interferon-induced protein 35 2.46773
PEX12 peroxisomal biogenesis factor 12 2.43328
KAT5 K(lysine) acetyltransferase 5 2.42826
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 2.4128
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 2.40471
SP1 Sp1 transcription factor 2.39893
PDCD7 programmed cell death 7 2.3983
NIT1 nitrilase 1 2.38162
MYEOV2 myeloma overexpressed 2 2.37923
DLG3 discs, large homolog 3 (Drosophila) 2.35943
ZSWIM7 zinc finger, SWIM-type containing 7 2.34034
RNF14 ring finger protein 14 2.3311
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.3309
XPR1 xenotropic and polytropic retrovirus receptor 1 2.32882
NUB1 negative regulator of ubiquitin-like proteins 1 2.32542
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 2.31664
TRAPPC9 trafficking protein particle complex 9 2.2902
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 2.28896
MFSD6 major facilitator superfamily domain containing 6 2.28081
MKRN1 makorin ring finger protein 1 2.28024
CDK20 cyclin-dependent kinase 20 2.27063
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 2.25208
YEATS2 YEATS domain containing 2 2.25167
TMA7 translation machinery associated 7 homolog (S. cerevisiae) 2.24921
SRP19 signal recognition particle 19kDa 2.22778
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 2.22346
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 2.21564
THNSL2 threonine synthase-like 2 (S. cerevisiae) 2.20611
APOPT1 apoptogenic 1, mitochondrial 2.19164
UBE2A ubiquitin-conjugating enzyme E2A 2.17939
TMEM5 transmembrane protein 5 2.17218
COLGALT1 collagen beta(1-O)galactosyltransferase 1 2.16035
PARP10 poly (ADP-ribose) polymerase family, member 10 2.15578
CIAO1 cytosolic iron-sulfur assembly component 1 2.13973
EHBP1 EH domain binding protein 1 2.13375
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) 2.13311
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 2.12912
ARPC5L actin related protein 2/3 complex, subunit 5-like 2.12897
MTX1 metaxin 1 2.12505
RNF167 ring finger protein 167 2.11604
AKIP1 A kinase (PRKA) interacting protein 1 2.11448
DESI2 desumoylating isopeptidase 2 2.10915
COASY CoA synthase 2.10484
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.10453
GBA glucosidase, beta, acid 2.09988
HEXB hexosaminidase B (beta polypeptide) 2.09779
UFC1 ubiquitin-fold modifier conjugating enzyme 1 2.07982
SOD1 superoxide dismutase 1, soluble 2.07371
DCTN3 dynactin 3 (p22) 2.0578
ZNF580 zinc finger protein 580 2.05321
KLHDC2 kelch domain containing 2 2.0447
PRKCSH protein kinase C substrate 80K-H 2.04327
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 2.04139
CR1L complement component (3b/4b) receptor 1-like 2.03806
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 2.03644
UROD uroporphyrinogen decarboxylase 2.02926
SECISBP2 SECIS binding protein 2 2.02863
TRIM41 tripartite motif containing 41 2.02748
TMEM50A transmembrane protein 50A 2.02701
TYW5 tRNA-yW synthesizing protein 5 2.01284
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 2.01256
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 2.01254
GOLGA7 golgin A7 2.0093
MED6 mediator complex subunit 6 2.00864
TMCO6 transmembrane and coiled-coil domains 6 2.00365
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.99602
MSRB2 methionine sulfoxide reductase B2 1.98291
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.98096
ENKD1 enkurin domain containing 1 1.9724
NDFIP1 Nedd4 family interacting protein 1 1.97191
PARP2 poly (ADP-ribose) polymerase 2 1.97167
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 1.96679
POGZ pogo transposable element with ZNF domain 1.96593
SAP30L SAP30-like 1.96439
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 1.96258
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 1.9609
TRAP1 TNF receptor-associated protein 1 1.95552
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 1.94787
TPT1 tumor protein, translationally-controlled 1 1.94783
AP3D1 adaptor-related protein complex 3, delta 1 subunit 1.94169
HMG20B high mobility group 20B 1.94139
ZDHHC16 zinc finger, DHHC-type containing 16 1.93955
IFT43 intraflagellar transport 43 1.93671
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 1.92901
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 1.92803
FBXO25 F-box protein 25 1.92152
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 1.92051
CHMP5 charged multivesicular body protein 5 1.9176
HACL1 2-hydroxyacyl-CoA lyase 1 1.91345
INSIG2 insulin induced gene 2 1.91336
CHD4 chromodomain helicase DNA binding protein 4 1.91022
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 1.90602
FBXW4 F-box and WD repeat domain containing 4 1.89837
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 1.89464
DTX3L deltex 3 like, E3 ubiquitin ligase 1.89453
RABGGTA Rab geranylgeranyltransferase, alpha subunit 1.89442
SPATA6 spermatogenesis associated 6 1.88855
LYRM1 LYR motif containing 1 1.87168
TMEM216 transmembrane protein 216 1.85542
MARK3 MAP/microtubule affinity-regulating kinase 3 1.85468
PSENEN presenilin enhancer gamma secretase subunit 1.84554
BBS9 Bardet-Biedl syndrome 9 1.84543
ASCC1 activating signal cointegrator 1 complex subunit 1 1.8442
SHARPIN SHANK-associated RH domain interactor 1.84239
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 1.83872
ASB8 ankyrin repeat and SOCS box containing 8 1.83235
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 1.83174
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 1.83142
PDE7A phosphodiesterase 7A 1.82704
IRF1 interferon regulatory factor 1 1.81853
DCAKD dephospho-CoA kinase domain containing 1.81837
TXNRD2 thioredoxin reductase 2 1.81781
TADA3 transcriptional adaptor 3 1.81691
ING4 inhibitor of growth family, member 4 1.81539
NECAP2 NECAP endocytosis associated 2 1.81335
B3GNT1 1.81128
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 1.80995
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 1.80921
MANBAL mannosidase, beta A, lysosomal-like 1.80877
HSPE1 heat shock 10kDa protein 1 1.80388
RPL21 ribosomal protein L21 1.80233
CENPV centromere protein V 1.7962
MED1 mediator complex subunit 1 1.79597
REXO1 REX1, RNA exonuclease 1 homolog (S. cerevisiae) 1.79305
MAGEE1 melanoma antigen family E1 1.79046
EI24 etoposide induced 2.4 1.78917
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 1.78869
UBXN1 UBX domain protein 1 1.78685
PRKCD protein kinase C, delta 1.78517
NDUFAF3 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 1.77823
SLC22A15 solute carrier family 22, member 15 1.77815
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 1.77569
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 1.77539
SCAF4 SR-related CTD-associated factor 4 1.77531
MRPL15 mitochondrial ribosomal protein L15 1.77011
KHSRP KH-type splicing regulatory protein 1.77011
ZNF524 zinc finger protein 524 1.7667
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 1.76537
CALCOCO1 calcium binding and coiled-coil domain 1 1.76507
PUM1 pumilio RNA-binding family member 1 1.7629
ALKBH3 alkB, alkylation repair homolog 3 (E. coli) 1.76202
NUP62 nucleoporin 62kDa 1.76118
COX19 COX19 cytochrome c oxidase assembly factor 1.76081
COX18 COX18 cytochrome c oxidase assembly factor 1.76081
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) 1.75875
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 1.74894
FLOT1 flotillin 1 1.74463
RNF111 ring finger protein 111 1.74336
NOSIP nitric oxide synthase interacting protein 1.73833
MSL1 male-specific lethal 1 homolog (Drosophila) 1.73618
CBY1 chibby homolog 1 (Drosophila) 1.73565
GLO1 glyoxalase I 1.7278
PAN3 PAN3 poly(A) specific ribonuclease subunit 1.72619
DNAL4 dynein, axonemal, light chain 4 1.72196
ECH1 enoyl CoA hydratase 1, peroxisomal 1.72113
AUH AU RNA binding protein/enoyl-CoA hydratase 1.72091
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 1.71504
RAB6A RAB6A, member RAS oncogene family 1.71287
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 1.71171
RNASEH2B ribonuclease H2, subunit B 1.7101
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 1.70984
C12ORF10 chromosome 12 open reading frame 10 1.70811
PPA2 pyrophosphatase (inorganic) 2 1.70701
FAM58A family with sequence similarity 58, member A 1.70672
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 1.70574
PPIA peptidylprolyl isomerase A (cyclophilin A) 1.70486
TMUB2 transmembrane and ubiquitin-like domain containing 2 1.70149
TM2D3 TM2 domain containing 3 1.69082
ACOT13 acyl-CoA thioesterase 13 1.68717
ZFHX4 zinc finger homeobox 4 1.68287
CGRRF1 cell growth regulator with ring finger domain 1 1.68155
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 1.68145
HTT huntingtin 1.6787
FAM63A family with sequence similarity 63, member A 1.67298
TSEN15 TSEN15 tRNA splicing endonuclease subunit 1.67236
XPO7 exportin 7 1.67187
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 1.67155
PDCD6 programmed cell death 6 1.66861
HDAC3 histone deacetylase 3 1.66851
MTFMT mitochondrial methionyl-tRNA formyltransferase 1.65872
IMP4 IMP4, U3 small nucleolar ribonucleoprotein 1.6576
PGM2 phosphoglucomutase 2 1.65721
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 1.65534
LRRC57 leucine rich repeat containing 57 1.65481
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.65461
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 1.65007
ABT1 activator of basal transcription 1 1.64955
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.64441
EYA3 EYA transcriptional coactivator and phosphatase 3 1.6426
CNOT8 CCR4-NOT transcription complex, subunit 8 1.64251
CHURC1 churchill domain containing 1 1.64172
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa 1.64162
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 1.6395
GAPDH glyceraldehyde-3-phosphate dehydrogenase 1.63909
GATAD1 GATA zinc finger domain containing 1 1.63562
COPZ1 coatomer protein complex, subunit zeta 1 1.63228
TBCD tubulin folding cofactor D 1.62953
RPRM reprimo, TP53 dependent G2 arrest mediator candidate 1.62348
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.61528
POLB polymerase (DNA directed), beta 1.61466
INPP1 inositol polyphosphate-1-phosphatase 1.61181
MINPP1 multiple inositol-polyphosphate phosphatase 1 1.60889
FAHD2B fumarylacetoacetate hydrolase domain containing 2B 1.60862
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 1.60762
CIB2 calcium and integrin binding family member 2 1.60506
TATDN2 TatD DNase domain containing 2 1.60436
EIF4H eukaryotic translation initiation factor 4H 1.60202
ANKRD46 ankyrin repeat domain 46 1.60197
SAMD4B sterile alpha motif domain containing 4B 1.60171
ATG3 autophagy related 3 1.59835
FOCAD focadhesin 1.59517
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.59308
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 1.59233
GPR107 G protein-coupled receptor 107 1.58957
ARL6 ADP-ribosylation factor-like 6 1.58849
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 1.58471
MTMR3 myotubularin related protein 3 1.58329
UBL7 ubiquitin-like 7 1.58286
SHROOM2 shroom family member 2 1.58228
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 1.5819
EAPP E2F-associated phosphoprotein 1.58103
SIKE1 suppressor of IKBKE 1 1.58101
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 1.57933
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 1.5792
ANK1 ankyrin 1, erythrocytic 1.57915
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 1.57878
SLC44A1 solute carrier family 44 (choline transporter), member 1 1.57805
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.57372
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) 1.57079
PABPC1 poly(A) binding protein, cytoplasmic 1 1.56975
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 1.56896
MRPL16 mitochondrial ribosomal protein L16 1.56812
CEP44 centrosomal protein 44kDa 1.5667
HMBS hydroxymethylbilane synthase 1.56528
TMBIM4 transmembrane BAX inhibitor motif containing 4 1.56472
FBXW5 F-box and WD repeat domain containing 5 1.56188
COX7B cytochrome c oxidase subunit VIIb 1.5613
RERE arginine-glutamic acid dipeptide (RE) repeats 1.56109
PDHB pyruvate dehydrogenase (lipoamide) beta 1.56089
ZC3HC1 zinc finger, C3HC-type containing 1 1.56071
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 1.55822
C12ORF57 chromosome 12 open reading frame 57 1.55773
TMX2 thioredoxin-related transmembrane protein 2 1.5561
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 1.556
CTNND1 catenin (cadherin-associated protein), delta 1 1.5543
TCAF2 TRPM8 channel-associated factor 2 1.55371
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 1.55345
SNX19 sorting nexin 19 1.55294
STAU1 staufen double-stranded RNA binding protein 1 1.54249
ADIPOR1 adiponectin receptor 1 1.54126
PRR14 proline rich 14 1.54024
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1 1.53797
UBE2J2 ubiquitin-conjugating enzyme E2, J2 1.53779
GLTSCR2 glioma tumor suppressor candidate region gene 2 1.53532
DOLK dolichol kinase 1.53492
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.5346
SMG9 SMG9 nonsense mediated mRNA decay factor 1.53438
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 1.53428
UBE2L6 ubiquitin-conjugating enzyme E2L 6 1.53412
BCDIN3D BCDIN3 domain containing 1.53292
EDF1 endothelial differentiation-related factor 1 1.53287
PTK2 protein tyrosine kinase 2 1.53194
HEXIM2 hexamethylene bis-acetamide inducible 2 1.52954
C2CD2 C2 calcium-dependent domain containing 2 1.52945
CLNS1A chloride channel, nucleotide-sensitive, 1A 1.52859
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 1.52787
NPR1 natriuretic peptide receptor 1 1.52769
AKIRIN2 akirin 2 1.52705
PHB2 prohibitin 2 1.52602
ATRAID all-trans retinoic acid-induced differentiation factor 1.52583
RPL19 ribosomal protein L19 1.52506
TMEM126B transmembrane protein 126B 1.52127

decreased expression

Symbol Name Standardized Value
COPA coatomer protein complex, subunit alpha -3.00365
SUCLG1 succinate-CoA ligase, alpha subunit -2.95268
ARL8B ADP-ribosylation factor-like 8B -2.92725
GARS glycyl-tRNA synthetase -2.92217
ACTR5 ARP5 actin-related protein 5 homolog (yeast) -2.78694
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.70095
RAB1A RAB1A, member RAS oncogene family -2.6775
JKAMP JNK1/MAPK8-associated membrane protein -2.64428
ZNF652 zinc finger protein 652 -2.6238
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae) -2.60303
TAGLN2 transgelin 2 -2.58833
NOL12 nucleolar protein 12 -2.55452
ABI1 abl-interactor 1 -2.52831
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -2.52292
AZIN1 antizyme inhibitor 1 -2.49557
CHKA choline kinase alpha -2.48017
P4HB prolyl 4-hydroxylase, beta polypeptide -2.47506
RAB22A RAB22A, member RAS oncogene family -2.46146
AMBP alpha-1-microglobulin/bikunin precursor -2.43179
NUP98 nucleoporin 98kDa -2.41832
TRAIP TRAF interacting protein -2.40172
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -2.39905
KANK1 KN motif and ankyrin repeat domains 1 -2.39316
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -2.38364
TMEM30A transmembrane protein 30A -2.35765
C1QBP complement component 1, q subcomponent binding protein -2.35363
DAZAP2 DAZ associated protein 2 -2.33975
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.31703
MTOR mechanistic target of rapamycin (serine/threonine kinase) -2.30472
INO80C INO80 complex subunit C -2.30193
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -2.29436
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 -2.28369
EIF5A eukaryotic translation initiation factor 5A -2.28077
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -2.27706
EIF3D eukaryotic translation initiation factor 3, subunit D -2.27647
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.27271
TSPAN5 tetraspanin 5 -2.27137
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -2.24783
PPP1R7 protein phosphatase 1, regulatory subunit 7 -2.21054
SAR1A secretion associated, Ras related GTPase 1A -2.2075
INTS5 integrator complex subunit 5 -2.18574
DGKD diacylglycerol kinase, delta 130kDa -2.17977
DSCR3 Down syndrome critical region 3 -2.16423
MPST mercaptopyruvate sulfurtransferase -2.09647
XPO6 exportin 6 -2.09078
MAN1B1 mannosidase, alpha, class 1B, member 1 -2.08592
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -2.08072
GRIP1 glutamate receptor interacting protein 1 -2.07724
EDEM2 ER degradation enhancer, mannosidase alpha-like 2 -2.07063
VCP valosin containing protein -2.06459
NUPL1 nucleoporin like 1 -2.04404
CEP78 centrosomal protein 78kDa -2.04306
SLC45A4 solute carrier family 45, member 4 -2.03653
WDR43 WD repeat domain 43 -2.01974
TESK1 testis-specific kinase 1 -2.01796
ANKRD28 ankyrin repeat domain 28 -2.01303
ARMC5 armadillo repeat containing 5 -2.01198
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -1.99431
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 -1.98669
TRIM35 tripartite motif containing 35 -1.9773
GSTM4 glutathione S-transferase mu 4 -1.97602
TUBA4A tubulin, alpha 4a -1.97599
TSN translin -1.96935
PDIA3 protein disulfide isomerase family A, member 3 -1.95199
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -1.94279
PQLC1 PQ loop repeat containing 1 -1.93477
NRCAM neuronal cell adhesion molecule -1.92087
ABR active BCR-related -1.91551
KIFC3 kinesin family member C3 -1.91432
NCKAP1 NCK-associated protein 1 -1.91328
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -1.9122
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1 -1.90991
COPG2 coatomer protein complex, subunit gamma 2 -1.90788
SCYL1 SCY1-like 1 (S. cerevisiae) -1.90481
APMAP adipocyte plasma membrane associated protein -1.90396
RSRC1 arginine/serine-rich coiled-coil 1 -1.90012
CYB5B cytochrome b5 type B (outer mitochondrial membrane) -1.89307
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) -1.89224
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -1.89071
SURF4 surfeit 4 -1.88686
WBP1L WW domain binding protein 1-like -1.87816
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) -1.87207
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -1.85426
CALR calreticulin -1.84965
RPS15A ribosomal protein S15a -1.84736
FBLIM1 filamin binding LIM protein 1 -1.84382
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 -1.8386
FOXA3 forkhead box A3 -1.83598
CHMP7 charged multivesicular body protein 7 -1.83447
UBIAD1 UbiA prenyltransferase domain containing 1 -1.83115
SYAP1 synapse associated protein 1 -1.83004
GLIS2 GLIS family zinc finger 2 -1.82797
PRMT5 protein arginine methyltransferase 5 -1.82682
PTGES3 prostaglandin E synthase 3 (cytosolic) -1.82633
MRPL38 mitochondrial ribosomal protein L38 -1.82605
FHDC1 FH2 domain containing 1 -1.8234
MARS2 methionyl-tRNA synthetase 2, mitochondrial -1.81326
VIMP VCP-interacting membrane selenoprotein -1.81219
ARFIP1 ADP-ribosylation factor interacting protein 1 -1.80503
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein -1.80443
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase -1.80422
TMPO thymopoietin -1.80092
ARCN1 archain 1 -1.79639
PTBP1 polypyrimidine tract binding protein 1 -1.78957
FAM114A1 family with sequence similarity 114, member A1 -1.77953
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) -1.77634
UBP1 upstream binding protein 1 (LBP-1a) -1.77624
UBQLN4 ubiquilin 4 -1.77389
PPAN peter pan homolog (Drosophila) -1.77022
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) -1.76499
UBL3 ubiquitin-like 3 -1.76259
NSF N-ethylmaleimide-sensitive factor -1.76113
TOX4 TOX high mobility group box family member 4 -1.75156
SLC35A4 solute carrier family 35, member A4 -1.7503
LSM12 LSM12 homolog (S. cerevisiae) -1.74146
THOC6 THO complex 6 -1.73913
NPDC1 neural proliferation, differentiation and control, 1 -1.72359
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -1.71821
FNDC3B fibronectin type III domain containing 3B -1.71526
INTS10 integrator complex subunit 10 -1.71394
FAM20C family with sequence similarity 20, member C -1.71054
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 -1.70727
MAT2A methionine adenosyltransferase II, alpha -1.70601
MBD3 methyl-CpG binding domain protein 3 -1.70251
PHB prohibitin -1.70061
PGBD5 piggyBac transposable element derived 5 -1.69669
IL6ST interleukin 6 signal transducer -1.69634
PDLIM1 PDZ and LIM domain 1 -1.69596
PBLD phenazine biosynthesis-like protein domain containing -1.69507
MED17 mediator complex subunit 17 -1.67905
TMEM214 transmembrane protein 214 -1.67228
ELOVL5 ELOVL fatty acid elongase 5 -1.67184
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -1.67036
PNN pinin, desmosome associated protein -1.66892
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa -1.66444
CFL2 cofilin 2 (muscle) -1.65751
PARVB parvin, beta -1.65672
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -1.6566
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -1.65655
KIF12 kinesin family member 12 -1.65533
TCF19 transcription factor 19 -1.65518
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase -1.65282
FAM120A family with sequence similarity 120A -1.64748
PDIA4 protein disulfide isomerase family A, member 4 -1.647
ANAPC1 anaphase promoting complex subunit 1 -1.64029
CINP cyclin-dependent kinase 2 interacting protein -1.63909
IPO5 importin 5 -1.63832
TXNDC11 thioredoxin domain containing 11 -1.6298
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) -1.62952
MEAF6 MYST/Esa1-associated factor 6 -1.62671
PYCR2 pyrroline-5-carboxylate reductase family, member 2 -1.62503
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -1.62319
INTS3 integrator complex subunit 3 -1.62092
PICALM phosphatidylinositol binding clathrin assembly protein -1.61316
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 -1.61095
LMF1 lipase maturation factor 1 -1.61004
ESAM endothelial cell adhesion molecule -1.60768
HDAC2 histone deacetylase 2 -1.60652
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -1.6051
GRIK5 glutamate receptor, ionotropic, kainate 5 -1.59462
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae) -1.59437
CDC42SE2 CDC42 small effector 2 -1.59282
PHRF1 PHD and ring finger domains 1 -1.59081
CKS1B CDC28 protein kinase regulatory subunit 1B -1.59028
SHMT1 serine hydroxymethyltransferase 1 (soluble) -1.58028
GTF2A2 general transcription factor IIA, 2, 12kDa -1.58007
GORASP2 golgi reassembly stacking protein 2, 55kDa -1.56586
SMYD2 SET and MYND domain containing 2 -1.5658
TUBGCP4 tubulin, gamma complex associated protein 4 -1.56541
GRB2 growth factor receptor-bound protein 2 -1.56525
CUL3 cullin 3 -1.56303
DCAF11 DDB1 and CUL4 associated factor 11 -1.56277
PDZK1IP1 PDZK1 interacting protein 1 -1.56067
EEF1G eukaryotic translation elongation factor 1 gamma -1.56042
CDR2 cerebellar degeneration-related protein 2, 62kDa -1.55971
CALU calumenin -1.55827
NFYA nuclear transcription factor Y, alpha -1.55798
ALG12 ALG12, alpha-1,6-mannosyltransferase -1.55603
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -1.54756
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 -1.54749
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 -1.54682
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.54566
M6PR mannose-6-phosphate receptor (cation dependent) -1.54205
BET1L Bet1 golgi vesicular membrane trafficking protein-like -1.54175
CTNNBL1 catenin, beta like 1 -1.54045
DCK deoxycytidine kinase -1.54036
THUMPD2 THUMP domain containing 2 -1.53919
SYNGR2 synaptogyrin 2 -1.53806
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa -1.53164
AKT1 v-akt murine thymoma viral oncogene homolog 1 -1.52564
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -1.52507
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -1.52261
NR2C2AP nuclear receptor 2C2-associated protein -1.52224
KLF9 Kruppel-like factor 9 -1.52019
STRBP spermatid perinuclear RNA binding protein -1.51601
SCAMP4 secretory carrier membrane protein 4 -1.51242
RALA v-ral simian leukemia viral oncogene homolog A (ras related) -1.50897
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -1.50868
BAG5 BCL2-associated athanogene 5 -1.50846
PDE4DIP phosphodiesterase 4D interacting protein -1.50819
GJD2 gap junction protein, delta 2, 36kDa -1.49689
EFHD2 EF-hand domain family, member D2 -1.49637
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -1.49532
SEC23B Sec23 homolog B (S. cerevisiae) -1.49458
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -1.49295
CHGA chromogranin A -1.49189
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 -1.49024
SEPHS1 selenophosphate synthetase 1 -1.48935
LAD1 ladinin 1 -1.48901
RAP1GAP RAP1 GTPase activating protein -1.47982
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -1.47554
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase -1.47549
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1 -1.47493
TRIP13 thyroid hormone receptor interactor 13 -1.47269
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase -1.471
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta -1.4704
ISYNA1 inositol-3-phosphate synthase 1 -1.4703
FKBP1A FK506 binding protein 1A, 12kDa -1.46971
EMD emerin -1.46838
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -1.46618
SHKBP1 SH3KBP1 binding protein 1 -1.46543
CCDC101 coiled-coil domain containing 101 -1.46433
NEU1 sialidase 1 (lysosomal sialidase) -1.46139
RIMBP2 RIMS binding protein 2 -1.45998
FAM45A family with sequence similarity 45, member A -1.45802
CTDNEP1 CTD nuclear envelope phosphatase 1 -1.45599
RYK receptor-like tyrosine kinase -1.45512
ING1 inhibitor of growth family, member 1 -1.45498
COA3 cytochrome c oxidase assembly factor 3 -1.45314
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 -1.45274
SPRYD3 SPRY domain containing 3 -1.45124
ANKRD54 ankyrin repeat domain 54 -1.4512
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 -1.44817
NARS asparaginyl-tRNA synthetase -1.44634
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) -1.44381
DDB1 damage-specific DNA binding protein 1, 127kDa -1.44278
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 -1.44265
ATP13A1 ATPase type 13A1 -1.44264
TBC1D25 TBC1 domain family, member 25 -1.44025
ZFP36L2 ZFP36 ring finger protein-like 2 -1.4376
ALS2 amyotrophic lateral sclerosis 2 (juvenile) -1.43657
GPSM2 G-protein signaling modulator 2 -1.43195
SCRIB scribbled planar cell polarity protein -1.43161
CD81 CD81 molecule -1.42863
MPI mannose phosphate isomerase -1.42859
GTF3A general transcription factor IIIA -1.42481
PDE3B phosphodiesterase 3B, cGMP-inhibited -1.42065
TCTA T-cell leukemia translocation altered -1.41899
CAB39 calcium binding protein 39 -1.41601
RAVER1 ribonucleoprotein, PTB-binding 1 -1.41576
KRT18 keratin 18, type I -1.41491
ARHGAP1 Rho GTPase activating protein 1 -1.41257
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 -1.41037
PDPK1 3-phosphoinositide dependent protein kinase 1 -1.40311
RTN4RL1 reticulon 4 receptor-like 1 -1.40007
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) -1.39984
HDLBP high density lipoprotein binding protein -1.39631
GCH1 GTP cyclohydrolase 1 -1.39585
GATA3 GATA binding protein 3 -1.3953
TSPAN9 tetraspanin 9 -1.39413
NUCB1 nucleobindin 1 -1.39066
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma -1.38969
TRAPPC5 trafficking protein particle complex 5 -1.38947
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -1.38939
CCDC12 coiled-coil domain containing 12 -1.3884
USPL1 ubiquitin specific peptidase like 1 -1.38308
RAB35 RAB35, member RAS oncogene family -1.38194
PTPRM protein tyrosine phosphatase, receptor type, M -1.37826
UBQLN1 ubiquilin 1 -1.37726
WDFY3 WD repeat and FYVE domain containing 3 -1.37431
RABIF RAB interacting factor -1.37406
HAPLN4 hyaluronan and proteoglycan link protein 4 -1.37398
GABARAP GABA(A) receptor-associated protein -1.37388
CHPF chondroitin polymerizing factor -1.37387
GOLPH3 golgi phosphoprotein 3 (coat-protein) -1.3734
SLC39A7 solute carrier family 39 (zinc transporter), member 7 -1.3723
PELO pelota homolog (Drosophila) -1.36957
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -1.36907
PFN1 profilin 1 -1.36877
MFSD2A major facilitator superfamily domain containing 2A -1.36874
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) -1.36715
CAPZB capping protein (actin filament) muscle Z-line, beta -1.36474
RAB3D RAB3D, member RAS oncogene family -1.36342
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 -1.36099
CDH23 cadherin-related 23 -1.36053
EPM2AIP1 EPM2A (laforin) interacting protein 1 -1.36027
PPP1R12C protein phosphatase 1, regulatory subunit 12C -1.36001
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c -1.35991
RPL13A ribosomal protein L13a -1.35779
ETF1 eukaryotic translation termination factor 1 -1.35672
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2 -1.35649
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) -1.35646
NTMT1 N-terminal Xaa-Pro-Lys N-methyltransferase 1 -1.35542
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -1.35488
KIF2A kinesin heavy chain member 2A -1.35346
MCRS1 microspherule protein 1 -1.35289
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -1.35283
SEC13 SEC13 homolog (S. cerevisiae) -1.35258
DOT1L DOT1-like histone H3K79 methyltransferase -1.35204
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -1.35145