Type 1 diabetes mellitus_Myocardial tissue_GSE4616 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4616
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Genes

600 genes differentially expressed during Type 1 diabetes mellitus_Myocardial tissue_GSE4616 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
SELENBP1 selenium binding protein 1 3.82458
TXNIP thioredoxin interacting protein 3.35329
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 3.33162
S100A13 S100 calcium binding protein A13 3.32723
MXI1 MAX interactor 1, dimerization protein 3.28672
FOXO3 forkhead box O3 3.0931
ACSS1 acyl-CoA synthetase short-chain family member 1 3.00634
ECH1 enoyl CoA hydratase 1, peroxisomal 3.00033
TMEM176B transmembrane protein 176B 2.96893
CAT catalase 2.94132
NR1H3 nuclear receptor subfamily 1, group H, member 3 2.92761
TBK1 TANK-binding kinase 1 2.86294
PDK4 pyruvate dehydrogenase kinase, isozyme 4 2.82609
RPL13 ribosomal protein L13 2.82254
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.79564
SMYD2 SET and MYND domain containing 2 2.76722
SELK selenoprotein K 2.76502
TIMP3 TIMP metallopeptidase inhibitor 3 2.75691
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 2.72935
VCAM1 vascular cell adhesion molecule 1 2.68608
BMP6 bone morphogenetic protein 6 2.66913
SPA17 sperm autoantigenic protein 17 2.66161
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 2.59486
EPB41L2 erythrocyte membrane protein band 4.1-like 2 2.58668
LEPROT leptin receptor overlapping transcript 2.58144
MYH7 myosin, heavy chain 7, cardiac muscle, beta 2.52771
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.48967
STX12 syntaxin 12 2.46646
INTS4 integrator complex subunit 4 2.43782
CTGF connective tissue growth factor 2.42162
FBP2 fructose-1,6-bisphosphatase 2 2.40389
RIT1 Ras-like without CAAX 1 2.3936
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.38384
LIMD1 LIM domains containing 1 2.37467
PKP4 plakophilin 4 2.37328
METTL20 methyltransferase like 20 2.37213
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 2.35806
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit 2.35091
RABGGTB Rab geranylgeranyltransferase, beta subunit 2.32721
RPS19 ribosomal protein S19 2.31466
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.30582
FAM171A1 family with sequence similarity 171, member A1 2.29953
CA4 carbonic anhydrase IV 2.27732
SNX6 sorting nexin 6 2.26964
PDK1 pyruvate dehydrogenase kinase, isozyme 1 2.26857
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 2.23421
LTC4S leukotriene C4 synthase 2.22485
THRAP3 thyroid hormone receptor associated protein 3 2.21531
CHMP3 charged multivesicular body protein 3 2.19643
RBL2 retinoblastoma-like 2 2.18742
RASL11B RAS-like, family 11, member B 2.18479
DPP7 dipeptidyl-peptidase 7 2.18302
RPL3 ribosomal protein L3 2.14796
FKBP5 FK506 binding protein 5 2.13056
CDC123 cell division cycle 123 2.12509
SMAD6 SMAD family member 6 2.10193
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 2.09408
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 2.08887
DLAT dihydrolipoamide S-acetyltransferase 2.07736
NQO1 NAD(P)H dehydrogenase, quinone 1 2.07643
CDO1 cysteine dioxygenase type 1 2.06301
SLK STE20-like kinase 2.05413
SUMO3 small ubiquitin-like modifier 3 2.04348
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 2.02529
MLYCD malonyl-CoA decarboxylase 2.02326
CIDEA cell death-inducing DFFA-like effector a 2.01805
TMEM176A transmembrane protein 176A 2.01737
PYGB phosphorylase, glycogen; brain 2.01436
CD36 CD36 molecule (thrombospondin receptor) 2.01192
DIAPH1 diaphanous-related formin 1 2.00906
CD63 CD63 molecule 1.99961
RPS23 ribosomal protein S23 1.99848
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 1.99263
HP1BP3 heterochromatin protein 1, binding protein 3 1.988
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K 1.97695
GTF2B general transcription factor IIB 1.97655
PLRG1 pleiotropic regulator 1 1.97378
ATRAID all-trans retinoic acid-induced differentiation factor 1.96672
PNP purine nucleoside phosphorylase 1.95551
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 1.9502
RASA3 RAS p21 protein activator 3 1.92307
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 1.92291
RPL27A ribosomal protein L27a 1.89705
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 1.88776
COMT catechol-O-methyltransferase 1.87973
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 1.87899
SESN1 sestrin 1 1.87862
ATG13 autophagy related 13 1.87589
PLAT plasminogen activator, tissue 1.87296
LCN2 lipocalin 2 1.86855
OSMR oncostatin M receptor 1.86135
LPL lipoprotein lipase 1.86035
GFPT2 glutamine-fructose-6-phosphate transaminase 2 1.8524
PLAC8 placenta-specific 8 1.85046
CORIN corin, serine peptidase 1.84682
FBXW2 F-box and WD repeat domain containing 2 1.84507
TNNI1 troponin I type 1 (skeletal, slow) 1.84453
LUC7L2 LUC7-like 2 (S. cerevisiae) 1.82603
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 1.79789
SAR1A secretion associated, Ras related GTPase 1A 1.79082
MYOM2 myomesin 2 1.78619
TINAGL1 tubulointerstitial nephritis antigen-like 1 1.77832
KIF1C kinesin family member 1C 1.77024
CLK4 CDC-like kinase 4 1.75612
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 1.75222
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 1.74913
MYEOV2 myeloma overexpressed 2 1.74817
KLF9 Kruppel-like factor 9 1.74237
NDRG1 N-myc downstream regulated 1 1.73937
TMEM222 transmembrane protein 222 1.73915
AMY2A amylase, alpha 2A (pancreatic) 1.73888
GADD45B growth arrest and DNA-damage-inducible, beta 1.735
ELMOD3 ELMO/CED-12 domain containing 3 1.73071
HELB helicase (DNA) B 1.7272
CLIP1 CAP-GLY domain containing linker protein 1 1.72354
EXOSC4 exosome component 4 1.72329
LARS leucyl-tRNA synthetase 1.72152
MFAP5 microfibrillar associated protein 5 1.71986
PEG3 paternally expressed 3 1.71433
ETFDH electron-transferring-flavoprotein dehydrogenase 1.71072
FKBP11 FK506 binding protein 11, 19 kDa 1.70805
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 1.7069
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.7031
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa 1.69976
GLIPR2 GLI pathogenesis-related 2 1.69408
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 1.6933
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 1.69264
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 1.68972
C12ORF57 chromosome 12 open reading frame 57 1.68506
PSIP1 PC4 and SFRS1 interacting protein 1 1.68327
TCN2 transcobalamin II 1.6829
PPL periplakin 1.66805
IFI16 interferon, gamma-inducible protein 16 1.65705
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 1.65572
CHMP2A charged multivesicular body protein 2A 1.64977
RIN2 Ras and Rab interactor 2 1.64718
HIST1H1C histone cluster 1, H1c 1.6438
BAX BCL2-associated X protein 1.64217
TMEM245 transmembrane protein 245 1.64063
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 1.64046
ECI1 enoyl-CoA delta isomerase 1 1.63967
BCL2L1 BCL2-like 1 1.63673
FAM134B family with sequence similarity 134, member B 1.63649
ETF1 eukaryotic translation termination factor 1 1.63611
PARM1 prostate androgen-regulated mucin-like protein 1 1.63451
LGALS4 lectin, galactoside-binding, soluble, 4 1.63084
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 1.62982
WDR61 WD repeat domain 61 1.62868
CLK1 CDC-like kinase 1 1.62838
IMP3 IMP3, U3 small nucleolar ribonucleoprotein 1.61465
DHRS4 dehydrogenase/reductase (SDR family) member 4 1.61285
RPL37A ribosomal protein L37a 1.5933
TUFT1 tuftelin 1 1.59042
MMP3 matrix metallopeptidase 3 1.58848
GABARAPL1 GABA(A) receptor-associated protein like 1 1.57048
CALU calumenin 1.5649
PDCL3 phosducin-like 3 1.56122
MMP14 matrix metallopeptidase 14 (membrane-inserted) 1.55723
ANGPTL4 angiopoietin-like 4 1.55642
FMNL3 formin-like 3 1.55502
APOD apolipoprotein D 1.55369
SP4 Sp4 transcription factor 1.55107
RER1 retention in endoplasmic reticulum sorting receptor 1 1.5483
ELP2 elongator acetyltransferase complex subunit 2 1.54479
NCOA3 nuclear receptor coactivator 3 1.54069
AP3B1 adaptor-related protein complex 3, beta 1 subunit 1.5326
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.52986
CBFB core-binding factor, beta subunit 1.52356
PRUNE prune exopolyphosphatase 1.51721
PXK PX domain containing serine/threonine kinase 1.51368
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 1.50294
ACTL6A actin-like 6A 1.50122
CAPZB capping protein (actin filament) muscle Z-line, beta 1.49733
SRSF2 serine/arginine-rich splicing factor 2 1.48215
PRPF38A pre-mRNA processing factor 38A 1.47695
ECI2 enoyl-CoA delta isomerase 2 1.47033
CLCN3 chloride channel, voltage-sensitive 3 1.46559
PLD1 phospholipase D1, phosphatidylcholine-specific 1.46527
CCDC152 coiled-coil domain containing 152 1.46317
TPST1 tyrosylprotein sulfotransferase 1 1.45547
CPSF2 cleavage and polyadenylation specific factor 2, 100kDa 1.45121
WBP5 WW domain binding protein 5 1.4502
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.44568
OGFR opioid growth factor receptor 1.44013
ZWINT ZW10 interacting kinetochore protein 1.43605
EIF5 eukaryotic translation initiation factor 5 1.42227
ZDHHC6 zinc finger, DHHC-type containing 6 1.42162
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 1.42081
MRPL50 mitochondrial ribosomal protein L50 1.41864
IL6ST interleukin 6 signal transducer 1.41653
BTBD1 BTB (POZ) domain containing 1 1.4114
PHKA1 phosphorylase kinase, alpha 1 (muscle) 1.4111
FLOT1 flotillin 1 1.40871
DDHD2 DDHD domain containing 2 1.40634
NDE1 nudE neurodevelopment protein 1 1.40461
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 1.40421
RUVBL1 RuvB-like AAA ATPase 1 1.40147
BRD1 bromodomain containing 1 1.39338
CPT1A carnitine palmitoyltransferase 1A (liver) 1.39253
NXPH4 neurexophilin 4 1.39213
GSN gelsolin 1.38776
LIFR leukemia inhibitory factor receptor alpha 1.38683
METTL9 methyltransferase like 9 1.37376
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 1.37055
ARMC10 armadillo repeat containing 10 1.36303
RERE arginine-glutamic acid dipeptide (RE) repeats 1.36284
TTC14 tetratricopeptide repeat domain 14 1.36252
ARHGAP21 Rho GTPase activating protein 21 1.36161
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 1.35814
PHLDA3 pleckstrin homology-like domain, family A, member 3 1.35485
TMEM159 transmembrane protein 159 1.35414
NPC1 Niemann-Pick disease, type C1 1.35381
LPCAT3 lysophosphatidylcholine acyltransferase 3 1.35268
ATXN10 ataxin 10 1.35198
CTPS2 CTP synthase 2 1.33977
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 1.33937
MGP matrix Gla protein 1.33834
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.33463
QRICH1 glutamine-rich 1 1.3337
ANGEL2 angel homolog 2 (Drosophila) 1.33306
PTPN14 protein tyrosine phosphatase, non-receptor type 14 1.32462
MECP2 methyl CpG binding protein 2 1.32426
NHP2 NHP2 ribonucleoprotein 1.32407
RABAC1 Rab acceptor 1 (prenylated) 1.3237
CP ceruloplasmin (ferroxidase) 1.32188
HMOX1 heme oxygenase 1 1.31992
TPD52 tumor protein D52 1.31955
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit 1.31913
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 1.31434
RAB9A RAB9A, member RAS oncogene family 1.30953
HLA-A major histocompatibility complex, class I, A 1.30863
ART3 ADP-ribosyltransferase 3 1.30819
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) 1.30424
ANAPC1 anaphase promoting complex subunit 1 1.30401
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.3033
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 1.29797
TMC6 transmembrane channel-like 6 1.28879
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 1.28732
CBX5 chromobox homolog 5 1.28687
FBXO21 F-box protein 21 1.28603
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.28589
DES desmin 1.28576
KCTD20 potassium channel tetramerization domain containing 20 1.27542
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 1.27528
MED23 mediator complex subunit 23 1.27181
IRX3 iroquois homeobox 3 1.27125
TRAPPC3 trafficking protein particle complex 3 1.27064
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1.2671
AHCYL1 adenosylhomocysteinase-like 1 1.26551
PTPRN protein tyrosine phosphatase, receptor type, N 1.26356
EMC2 ER membrane protein complex subunit 2 1.26295
HABP2 hyaluronan binding protein 2 1.25842
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) 1.25757
TMED3 transmembrane emp24 protein transport domain containing 3 1.25213
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 1.24863
SHFM1 split hand/foot malformation (ectrodactyly) type 1 1.24719
MARS methionyl-tRNA synthetase 1.24663
CUL1 cullin 1 1.23647
YBX1 Y box binding protein 1 1.23522
SIN3B SIN3 transcription regulator family member B 1.23459
MINA MYC induced nuclear antigen 1.23436
PLA2G12A phospholipase A2, group XIIA 1.23185
FAM173A family with sequence similarity 173, member A 1.23182
RETSAT retinol saturase (all-trans-retinol 13,14-reductase) 1.23017
PTPN9 protein tyrosine phosphatase, non-receptor type 9 1.22808
GLUL glutamate-ammonia ligase 1.22689
ATPIF1 ATPase inhibitory factor 1 1.22642
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 1.22426
THUMPD1 THUMP domain containing 1 1.21784
EIF3E eukaryotic translation initiation factor 3, subunit E 1.2172
CLEC4D C-type lectin domain family 4, member D 1.21602
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.21423
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 1.21353
CFD complement factor D (adipsin) 1.20893
HOXB2 homeobox B2 1.20871
SAP30BP SAP30 binding protein 1.20807
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 1.20499
MRPL39 mitochondrial ribosomal protein L39 1.19788
PIM3 Pim-3 proto-oncogene, serine/threonine kinase 1.1956
SKAP2 src kinase associated phosphoprotein 2 1.19491
CDK8 cyclin-dependent kinase 8 1.19119
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.19078
BDNF brain-derived neurotrophic factor 1.18806
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 1.18671
RPL10 ribosomal protein L10 1.1849
SPP1 secreted phosphoprotein 1 1.18007
DPEP1 dipeptidase 1 (renal) 1.17999
TARS threonyl-tRNA synthetase 1.17552
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) 1.17276
DYNLRB1 dynein, light chain, roadblock-type 1 1.16973
SAT1 spermidine/spermine N1-acetyltransferase 1 1.16849
ISG15 ISG15 ubiquitin-like modifier 1.16844
SHROOM3 shroom family member 3 1.16839
FAS Fas cell surface death receptor 1.16665
PKN2 protein kinase N2 1.1628
ACAA2 acetyl-CoA acyltransferase 2 1.16218
UBL5 ubiquitin-like 5 1.16029
SYF2 SYF2 pre-mRNA-splicing factor 1.15348
EEF2 eukaryotic translation elongation factor 2 1.14725
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 1.14444

decreased expression

Symbol Name Standardized Value
ATXN2 ataxin 2 -4.12635
WWTR1 WW domain containing transcription regulator 1 -3.94045
MTCH1 mitochondrial carrier 1 -3.80916
OSBP oxysterol binding protein -3.78374
CS citrate synthase -3.59587
CSNK2A1 casein kinase 2, alpha 1 polypeptide -3.53388
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -3.53379
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -3.51692
PPA1 pyrophosphatase (inorganic) 1 -3.51522
TMX2 thioredoxin-related transmembrane protein 2 -3.44304
CENPBD1 CENPB DNA-binding domains containing 1 -3.39581
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -3.3374
AK4 adenylate kinase 4 -3.31378
MRPL37 mitochondrial ribosomal protein L37 -3.28416
NHP2L1 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) -3.26823
CXCL12 chemokine (C-X-C motif) ligand 12 -3.2641
SPRYD4 SPRY domain containing 4 -3.16707
USP24 ubiquitin specific peptidase 24 -3.09057
REEP5 receptor accessory protein 5 -3.08903
SAE1 SUMO1 activating enzyme subunit 1 -3.05677
EDF1 endothelial differentiation-related factor 1 -3.03628
CFDP1 craniofacial development protein 1 -3.03268
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -2.97823
EIF1B eukaryotic translation initiation factor 1B -2.96252
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.95324
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -2.91039
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.68843
LPIN1 lipin 1 -2.67778
NFS1 NFS1 cysteine desulfurase -2.67683
RBMS2 RNA binding motif, single stranded interacting protein 2 -2.65228
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -2.63916
RANGRF RAN guanine nucleotide release factor -2.63629
MRPS25 mitochondrial ribosomal protein S25 -2.62803
TNNT1 troponin T type 1 (skeletal, slow) -2.62353
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.6166
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa -2.61654
MYADM myeloid-associated differentiation marker -2.61404
CPOX coproporphyrinogen oxidase -2.58354
TMEM14C transmembrane protein 14C -2.57213
ROM1 retinal outer segment membrane protein 1 -2.57181
MTIF2 mitochondrial translational initiation factor 2 -2.5064
GPC1 glypican 1 -2.50498
SCMH1 sex comb on midleg homolog 1 (Drosophila) -2.48715
MYH9 myosin, heavy chain 9, non-muscle -2.47504
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -2.46653
SERF2 small EDRK-rich factor 2 -2.46144
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 -2.44431
COQ10A coenzyme Q10 homolog A (S. cerevisiae) -2.43833
THRSP thyroid hormone responsive -2.40872
FASN fatty acid synthase -2.40515
FKBP4 FK506 binding protein 4, 59kDa -2.37935
KRTCAP2 keratinocyte associated protein 2 -2.37593
ELOVL5 ELOVL fatty acid elongase 5 -2.36283
SHE Src homology 2 domain containing E -2.36017
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 -2.35764
DGUOK deoxyguanosine kinase -2.32556
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.31345
ENO3 enolase 3 (beta, muscle) -2.31142
DYNLL2 dynein, light chain, LC8-type 2 -2.29544
CTSC cathepsin C -2.29419
HAGH hydroxyacylglutathione hydrolase -2.28172
BBS4 Bardet-Biedl syndrome 4 -2.23506
AATK apoptosis-associated tyrosine kinase -2.23123
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.22876
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.2257
CRTAP cartilage associated protein -2.22239
HIGD2A HIG1 hypoxia inducible domain family, member 2A -2.20436
CLIC4 chloride intracellular channel 4 -2.19736
RBM17 RNA binding motif protein 17 -2.19704
BAG2 BCL2-associated athanogene 2 -2.1902
PRDX5 peroxiredoxin 5 -2.1893
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 -2.17387
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -2.14226
FASTK Fas-activated serine/threonine kinase -2.13327
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.1283
MRPL18 mitochondrial ribosomal protein L18 -2.1248
BABAM1 BRISC and BRCA1 A complex member 1 -2.12049
ANXA4 annexin A4 -2.114
ACAA1 acetyl-CoA acyltransferase 1 -2.10967
NKAIN1 Na+/K+ transporting ATPase interacting 1 -2.08756
PGK1 phosphoglycerate kinase 1 -2.08666
FAM101B family with sequence similarity 101, member B -2.07247
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.05035
CTSF cathepsin F -2.04786
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) -2.03952
MRPS15 mitochondrial ribosomal protein S15 -2.0363
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -2.03025
UBQLN4 ubiquilin 4 -2.01808
MAP2K3 mitogen-activated protein kinase kinase 3 -2.00851
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 -1.99887
MRPS36 mitochondrial ribosomal protein S36 -1.99705
FRMD6 FERM domain containing 6 -1.97895
BHLHE40 basic helix-loop-helix family, member e40 -1.96318
CD81 CD81 molecule -1.96316
PTDSS1 phosphatidylserine synthase 1 -1.95211
TYSND1 trypsin domain containing 1 -1.94713
MRPL4 mitochondrial ribosomal protein L4 -1.94213
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta -1.93369
ALAD aminolevulinate dehydratase -1.93332
POLR1E polymerase (RNA) I polypeptide E, 53kDa -1.92971
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -1.92238
ACOT7 acyl-CoA thioesterase 7 -1.9135
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) -1.90845
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -1.9029
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 -1.90216
HOXB5 homeobox B5 -1.89714
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa -1.88706
SRSF6 serine/arginine-rich splicing factor 6 -1.88667
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -1.88449
PGAM2 phosphoglycerate mutase 2 (muscle) -1.88366
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -1.88301
RTN2 reticulon 2 -1.87918
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -1.86407
SETD8 SET domain containing (lysine methyltransferase) 8 -1.86228
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -1.85923
HSPH1 heat shock 105kDa/110kDa protein 1 -1.85668
MYH6 myosin, heavy chain 6, cardiac muscle, alpha -1.85364
MRPS7 mitochondrial ribosomal protein S7 -1.84758
NMT1 N-myristoyltransferase 1 -1.83665
FHOD3 formin homology 2 domain containing 3 -1.83542
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 -1.83322
ZNHIT1 zinc finger, HIT-type containing 1 -1.82696
PAK1IP1 PAK1 interacting protein 1 -1.81485
CLPTM1L CLPTM1-like -1.80575
SOX7 SRY (sex determining region Y)-box 7 -1.80322
BECN1 beclin 1, autophagy related -1.79545
PPIC peptidylprolyl isomerase C (cyclophilin C) -1.7923
ARFRP1 ADP-ribosylation factor related protein 1 -1.77865
TMEM97 transmembrane protein 97 -1.77695
CPXM2 carboxypeptidase X (M14 family), member 2 -1.77594
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 -1.75803
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase -1.75158
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -1.74834
TMED9 transmembrane emp24 protein transport domain containing 9 -1.74737
TSFM Ts translation elongation factor, mitochondrial -1.74333
TRAF3 TNF receptor-associated factor 3 -1.73981
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -1.73919
MRPS31 mitochondrial ribosomal protein S31 -1.7321
NR2F6 nuclear receptor subfamily 2, group F, member 6 -1.71301
SDHAF1 succinate dehydrogenase complex assembly factor 1 -1.71272
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 -1.71178
WBP1 WW domain binding protein 1 -1.71174
CLTA clathrin, light chain A -1.70331
MRPL45 mitochondrial ribosomal protein L45 -1.7006
SYS1 Sys1 golgi trafficking protein -1.69803
ZCRB1 zinc finger CCHC-type and RNA binding motif 1 -1.69447
GSTP1 glutathione S-transferase pi 1 -1.68557
HIST1H2BI histone cluster 1, H2bi -1.68282
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -1.67945
MRPL28 mitochondrial ribosomal protein L28 -1.67919
ODC1 ornithine decarboxylase 1 -1.67804
ACSF3 acyl-CoA synthetase family member 3 -1.6756
EMCN endomucin -1.67381
GFM1 G elongation factor, mitochondrial 1 -1.67134
FAM102A family with sequence similarity 102, member A -1.66874
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial) -1.66861
HTRA1 HtrA serine peptidase 1 -1.6668
PRDM5 PR domain containing 5 -1.66069
RNASEH2C ribonuclease H2, subunit C -1.65977
CD200 CD200 molecule -1.64698
PHLDA1 pleckstrin homology-like domain, family A, member 1 -1.64249
RORC RAR-related orphan receptor C -1.64164
SNX3 sorting nexin 3 -1.63941
PLA2G5 phospholipase A2, group V -1.63595
RNF208 ring finger protein 208 -1.63093
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 -1.62936
ZDHHC5 zinc finger, DHHC-type containing 5 -1.62901
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -1.62783
DTYMK deoxythymidylate kinase (thymidylate kinase) -1.62068
CLNS1A chloride channel, nucleotide-sensitive, 1A -1.6176
ATOX1 antioxidant 1 copper chaperone -1.61039
USP2 ubiquitin specific peptidase 2 -1.60956
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.60868
CDH5 cadherin 5, type 2 (vascular endothelium) -1.6074
DDT D-dopachrome tautomerase -1.6073
SYNGR2 synaptogyrin 2 -1.60447
ACTG1 actin gamma 1 -1.60441
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -1.60327
GPI glucose-6-phosphate isomerase -1.59983
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -1.59708
UROS uroporphyrinogen III synthase -1.59595
TPP1 tripeptidyl peptidase I -1.58711
UQCRC1 ubiquinol-cytochrome c reductase core protein I -1.57604
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -1.57518
RHOA ras homolog family member A -1.57207
LONP1 lon peptidase 1, mitochondrial -1.57072
FYN FYN proto-oncogene, Src family tyrosine kinase -1.56402
GALR2 galanin receptor 2 -1.56362
PCYOX1 prenylcysteine oxidase 1 -1.55967
RPN1 ribophorin I -1.54953
PHB prohibitin -1.54698
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -1.54622
C6ORF136 chromosome 6 open reading frame 136 -1.54196
TRAF2 TNF receptor-associated factor 2 -1.5354
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -1.53506
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -1.53307
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 -1.53155
EIF3D eukaryotic translation initiation factor 3, subunit D -1.53105
SNX9 sorting nexin 9 -1.52782
ERGIC3 ERGIC and golgi 3 -1.52461
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -1.52349
PIGS phosphatidylinositol glycan anchor biosynthesis, class S -1.51986
VASP vasodilator-stimulated phosphoprotein -1.5136
HSPB2 heat shock 27kDa protein 2 -1.50999
EFNB3 ephrin-B3 -1.50497
SYAP1 synapse associated protein 1 -1.50446
AOC3 amine oxidase, copper containing 3 -1.50207
FRRS1 ferric-chelate reductase 1 -1.50102
MDP1 magnesium-dependent phosphatase 1 -1.50052
PNKD paroxysmal nonkinesigenic dyskinesia -1.49656
PCID2 PCI domain containing 2 -1.49562
GCK glucokinase (hexokinase 4) -1.48908
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow -1.48291
RP9 retinitis pigmentosa 9 (autosomal dominant) -1.48053
KCMF1 potassium channel modulatory factor 1 -1.4786
FAM69B family with sequence similarity 69, member B -1.47689
TCEB3 transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) -1.47466
HTT huntingtin -1.47355
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -1.46704
LTBP4 latent transforming growth factor beta binding protein 4 -1.46398
NANS N-acetylneuraminic acid synthase -1.46285
N4BP1 NEDD4 binding protein 1 -1.46265
MPDZ multiple PDZ domain protein -1.46219
ALAS1 5'-aminolevulinate synthase 1 -1.45993
CDC45 cell division cycle 45 -1.45935
TRAPPC4 trafficking protein particle complex 4 -1.45743
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -1.45689
LGALS1 lectin, galactoside-binding, soluble, 1 -1.45482
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -1.45255
SNX1 sorting nexin 1 -1.45163
MRPL42 mitochondrial ribosomal protein L42 -1.44692
COL15A1 collagen, type XV, alpha 1 -1.44569
MID1IP1 MID1 interacting protein 1 -1.44459
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -1.44426
TRAPPC1 trafficking protein particle complex 1 -1.44358
CA8 carbonic anhydrase VIII -1.44267
PDLIM4 PDZ and LIM domain 4 -1.43971
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -1.43609
MRPS11 mitochondrial ribosomal protein S11 -1.43286
PRCC papillary renal cell carcinoma (translocation-associated) -1.43216
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative) -1.42445
SLC31A1 solute carrier family 31 (copper transporter), member 1 -1.42357
FAM13B family with sequence similarity 13, member B -1.42332
STARD10 StAR-related lipid transfer (START) domain containing 10 -1.421
CLCN7 chloride channel, voltage-sensitive 7 -1.41474
GNPAT glyceronephosphate O-acyltransferase -1.41459
MYDGF myeloid-derived growth factor -1.41228
RPIA ribose 5-phosphate isomerase A -1.41106
HIST1H3C histone cluster 1, H3c -1.40945
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -1.40918
NICN1 nicolin 1 -1.40894
FBXW11 F-box and WD repeat domain containing 11 -1.40456
SLC35E1 solute carrier family 35, member E1 -1.40387
MAPK12 mitogen-activated protein kinase 12 -1.39929
UBXN1 UBX domain protein 1 -1.39649
HSF1 heat shock transcription factor 1 -1.3964
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase -1.39413
CCDC93 coiled-coil domain containing 93 -1.39214
MYL1 myosin, light chain 1, alkali; skeletal, fast -1.38832
TMEM70 transmembrane protein 70 -1.38813
SARS seryl-tRNA synthetase -1.38721
PIGT phosphatidylinositol glycan anchor biosynthesis, class T -1.38559
COL4A1 collagen, type IV, alpha 1 -1.37507
MEOX1 mesenchyme homeobox 1 -1.37421
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B -1.37031
FEZ2 fasciculation and elongation protein zeta 2 (zygin II) -1.36746
RBMX RNA binding motif protein, X-linked -1.36619
BRD7 bromodomain containing 7 -1.36574
RNF166 ring finger protein 166 -1.36342
TXNRD1 thioredoxin reductase 1 -1.36022
PRKCB protein kinase C, beta -1.35968
FKBP9 FK506 binding protein 9, 63 kDa -1.35855
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -1.35743
PFKM phosphofructokinase, muscle -1.35373
RGS6 regulator of G-protein signaling 6 -1.35174
SLCO5A1 solute carrier organic anion transporter family, member 5A1 -1.34618
CCND1 cyclin D1 -1.34375
DDAH2 dimethylarginine dimethylaminohydrolase 2 -1.33614
REXO2 RNA exonuclease 2 -1.33543
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -1.33511
G6PC3 glucose 6 phosphatase, catalytic, 3 -1.33352
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 -1.32743
FOSL2 FOS-like antigen 2 -1.32656
NME1 NME/NM23 nucleoside diphosphate kinase 1 -1.32409
KCNK3 potassium channel, two pore domain subfamily K, member 3 -1.32358
CCNL2 cyclin L2 -1.31546
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -1.31014
HIGD1A HIG1 hypoxia inducible domain family, member 1A -1.31014
CHEK2 checkpoint kinase 2 -1.30114
EFNA3 ephrin-A3 -1.3006
CAMK2B calcium/calmodulin-dependent protein kinase II beta -1.3
TKT transketolase -1.29783
NKIRAS1 NFKB inhibitor interacting Ras-like 1 -1.29294
PTCD2 pentatricopeptide repeat domain 2 -1.28873
SRPK2 SRSF protein kinase 2 -1.28685
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -1.28622
TGFB3 transforming growth factor, beta 3 -1.28527
LDHA lactate dehydrogenase A -1.28398
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit -1.28238
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -1.27955