Tourette Syndrome Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A tic disorder that is characterized by multiple physical (motor) tics and at least one vocal (phonic) tic present for more than a year. (Human Disease Ontology, DOID_11119)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D005879
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Genes

36 genes/proteins associated with the disease Tourette Syndrome from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
GTS Gilles de la Tourette syndrome 2.88009
SLITRK1 SLIT and NTRK-like family, member 1 2.88009
DRD3 dopamine receptor D3 2.88009
DRD2 dopamine receptor D2 1.99961
BDNF brain-derived neurotrophic factor 1.81921
PRL prolactin 1.64258
HOMER1 homer scaffolding protein 1 1.60035
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.56312
TH tyrosine hydroxylase 1.54986
OPRM1 opioid receptor, mu 1 1.5462
FOS FBJ murine osteosarcoma viral oncogene homolog 1.52161
EGR1 early growth response 1 1.42428
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.40204
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 1.38752
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 1.36304
CAT catalase 1.35502
AVP arginine vasopressin 1.32786
PENK proenkephalin 1.30451
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 1.30117
OPRD1 opioid receptor, delta 1 1.27751
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 1.254
ARC activity-regulated cytoskeleton-associated protein 1.25183
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.19933
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.19704
MAOB monoamine oxidase B 1.14954
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 1.13313
CRH corticotropin releasing hormone 1.13143
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.11877
GSK3B glycogen synthase kinase 3 beta 1.09436
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.09436
TNF tumor necrosis factor 1.0766
BCL2 B-cell CLL/lymphoma 2 1.07625
COMT catechol-O-methyltransferase 1.05972
OPRK1 opioid receptor, kappa 1 1.04088
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 1.03641
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.03456